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Protein

Protein LIN1

Gene

LIN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31191-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LIN1
Gene namesi
Name:LIN1
Ordered Locus Names:YHR156C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR156C.
SGDiS000001199. LIN1.

Subcellular locationi

  • Nucleus 1 Publication

  • Note: Probably associated with chromatin.

GO - Cellular componenti

  • chromatin Source: SGD
  • nucleus Source: SGD
  • U5 snRNP Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340Protein LIN1PRO_0000195038Add
BLAST

Proteomic databases

MaxQBiP38852.

Interactioni

Subunit structurei

Interacts with the cohesin subunit IRR1. Interacts with PRP8, HEX3, NFI1, WSS1, RFC1 and YJL149W.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
PRP8P333343EBI-570,EBI-465

Protein-protein interaction databases

BioGridi36590. 56 interactions.
DIPiDIP-4407N.
IntActiP38852. 12 interactions.
MINTiMINT-552042.

Structurei

3D structure databases

ProteinModelPortaliP38852.
SMRiP38852. Positions 282-336.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini282 – 34059GYFPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the LIN1 family.Curated
Contains 1 GYF domain.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiP38852.
KOiK13099.
OMAiWIDEVED.
OrthoDBiEOG092C5II0.

Family and domain databases

InterProiIPR003169. GYF.
[Graphical view]
PfamiPF02213. GYF. 1 hit.
[Graphical view]
SMARTiSM00444. GYF. 1 hit.
[Graphical view]
SUPFAMiSSF55277. SSF55277. 1 hit.
PROSITEiPS50829. GYF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38852-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYTQYPNSS KLKRNSDRRE HDEKLSDELH NQSTIYEDEE LSRAEYDSDS
60 70 80 90 100
DSSVEDSTDN ENSGKEMDEK SYEKNEDHVE DHRKRKKSKI QLLDIAEFKK
110 120 130 140 150
ENLADLDYQI GNSESKVEKG VNIEPFNIDD EIKHGVFDKD GNYIKTENAT
160 170 180 190 200
ENDQQDNEEW MNDVINTEEV NRLEKEQSVK TQNSRHYMVH EALNLLKFFL
210 220 230 240 250
VDENETVLES LGRLNKLRKI AISKKNKSLK YVIHGIELLS DLINILEKKG
260 270 280 290 300
FSEVYEYNRL KVQDAIEEEI FDDSSRIVNH KTKLWGFKWL NKLDEYHGLY
310 320 330 340
TNYEMSYWQK SYFKNSVIVK FHSEPDRDEN WIHVSCLSFM
Length:340
Mass (Da):40,369
Last modified:February 1, 1995 - v1
Checksum:i59A10D63E0C8715C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10397 Genomic DNA. Translation: AAB68990.1.
AY557881 Genomic DNA. Translation: AAS56207.1.
BK006934 Genomic DNA. Translation: DAA06849.1.
PIRiS46768.
RefSeqiNP_012026.1. NM_001179287.1.

Genome annotation databases

EnsemblFungiiYHR156C; YHR156C; YHR156C.
GeneIDi856561.
KEGGisce:YHR156C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10397 Genomic DNA. Translation: AAB68990.1.
AY557881 Genomic DNA. Translation: AAS56207.1.
BK006934 Genomic DNA. Translation: DAA06849.1.
PIRiS46768.
RefSeqiNP_012026.1. NM_001179287.1.

3D structure databases

ProteinModelPortaliP38852.
SMRiP38852. Positions 282-336.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36590. 56 interactions.
DIPiDIP-4407N.
IntActiP38852. 12 interactions.
MINTiMINT-552042.

Proteomic databases

MaxQBiP38852.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR156C; YHR156C; YHR156C.
GeneIDi856561.
KEGGisce:YHR156C.

Organism-specific databases

EuPathDBiFungiDB:YHR156C.
SGDiS000001199. LIN1.

Phylogenomic databases

InParanoidiP38852.
KOiK13099.
OMAiWIDEVED.
OrthoDBiEOG092C5II0.

Enzyme and pathway databases

BioCyciYEAST:G3O-31191-MONOMER.

Miscellaneous databases

PROiP38852.

Family and domain databases

InterProiIPR003169. GYF.
[Graphical view]
PfamiPF02213. GYF. 1 hit.
[Graphical view]
SMARTiSM00444. GYF. 1 hit.
[Graphical view]
SUPFAMiSSF55277. SSF55277. 1 hit.
PROSITEiPS50829. GYF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLIN1_YEAST
AccessioniPrimary (citable) accession number: P38852
Secondary accession number(s): D3DLA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 799 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.