P38852 (LIN1_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 84.
History...
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Protein LIN1 | ||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||
| Taxonomic identifier | 559292 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 340 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Subunit structure | Interacts with the cohesin subunit IRR1. Interacts with PRP8, HEX3, NFI1, WSS1, RFC1 and YJL149W. Ref.4 |
| Subcellular location | |
| Miscellaneous | Present with 799 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | Belongs to the LIN1 family. Contains 1 GYF domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Nucleus |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular component | U5 snRNP Inferred from direct assay. Source: SGD chromatinInferred from direct assay Ref.4. Source: SGD |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| PRP8 | P33334 | 3 | EBI-570,EBI-465 |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. Vaudin M.Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [2] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [3] | "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J.Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | "Proteins interacting with Lin 1p, a putative link between chromosome segregation, mRNA splicing and DNA replication in Saccharomyces cerevisiae." Bialkowska A., Kurlandzka A. Yeast 19:1323-1333(2002) [PubMed: 12402242] [Abstract] Cited for: SUBCELLULAR LOCATION, INTERACTION WITH IRR1; PRP8; HEX3; NFI1; WSS1; RFC1 AND YJL149W. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U10397 Genomic DNA. Translation: AAB68990.1. AY557881 Genomic DNA. Translation: AAS56207.1. BK006934 Genomic DNA. Translation: DAA06849.1. |
| PIR | S46768. |
| RefSeq | NP_012026.1. NM_001179287.1. |
3D structure databases | |
| ProteinModelPortal | P38852. |
| SMR | P38852. Positions 282-339. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-4407N. |
| IntAct | P38852. 12 interactions. |
| MINT | MINT-552042. |
| STRING | P38852. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YHR156C; YHR156C; YHR156C. |
| GeneID | 856561. |
| KEGG | sce:YHR156C. |
| NMPDR | fig|4932.3.peg.3190. |
Organism-specific databases | |
| CYGD | YHR156c. |
| SGD | S000001199. LIN1. |
Phylogenomic databases | |
| eggNOG | fuNOG11633. |
| OMA | MQYWKEN. |
| OrthoDB | EOG4KSSVF. |
Gene expression databases | |
| ArrayExpress | P38852. |
| Genevestigator | P38852. |
| GermOnline | YHR156C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR003169. GYF. [Graphical view] |
| Pfam | PF02213. GYF. 1 hit. [Graphical view] |
| SMART | SM00444. GYF. 1 hit. [Graphical view] |
| PROSITE | PS50829. GYF. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 982387. |
Entry information
| Entry name | LIN1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P38852 Secondary accession number(s): D3DLA5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome VIII Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with