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Protein

Peroxisomal membrane protein PEX28

Gene

PEX28

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the regulation of peroxisome number, size and distribution.1 Publication

GO - Biological processi

  • peroxisome organization Source: SGD

Keywordsi

Biological processPeroxisome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-31185-MONOMER

Protein family/group databases

TCDBi3.A.20.1.5 the peroxisomal protein importer (ppi) family

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PEX28
Alternative name(s):
Peroxin-28
Gene namesi
Name:PEX28
Ordered Locus Names:YHR150W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR150W
SGDiS000001193 PEX28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 243CytoplasmicSequence analysisAdd BLAST243
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Topological domaini265 – 392PeroxisomalSequence analysisAdd BLAST128
Transmembranei393 – 413HelicalSequence analysisAdd BLAST21
Topological domaini414 – 579CytoplasmicSequence analysisAdd BLAST166

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002029251 – 579Peroxisomal membrane protein PEX28Add BLAST579

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi361N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiP38848
PaxDbiP38848
PRIDEiP38848

PTM databases

iPTMnetiP38848

Interactioni

Protein-protein interaction databases

BioGridi36584, 59 interactors
STRINGi4932.YHR150W

Structurei

3D structure databases

ProteinModelPortaliP38848
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 114Ser-richAdd BLAST113

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000069406
HOGENOMiHOG000115507
InParanoidiP38848
OMAiWRLIFIQ
OrthoDBiEOG092C1HJD

Family and domain databases

InterProiView protein in InterPro
IPR010482 Peroxin
PfamiView protein in Pfam
PF06398 Pex24p, 1 hit

Sequencei

Sequence statusi: Complete.

P38848-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSETSSSRRS ASKDAVKSYF AGKYNKVLDS ILEAEAAISK SPTVAEDLSG
60 70 80 90 100
SSSSGNSEMS HPSLTASSAT SQGISKKELL QQIAGSLFST SIERLKTAHS
110 120 130 140 150
SEVSSTPEYS VNDSYGEQEC RECDGVFKCS AHFEGAPEYY DDETESGPAL
160 170 180 190 200
EPMTSNSEKD PFIDVFLDKL ISRLVPEKLP EREHFSSKTT IEHDLDTGRV
210 220 230 240 250
PVFSATTLGS NFKKLSKKMG SIFELQDSIV RLLTWRNPTG TVTSLILFTL
260 270 280 290 300
ICFNPMYLVI LPIFRFVYGI VVPGYVRKHP LQRSIYPLKR NHGSSLLYDV
310 320 330 340 350
CYEGKNEYSY GQQFFSKSFM DTLESRNQEI DEISELDKRT ENTGELKQGM
360 370 380 390 400
KVLINLRDMQ NMTSGTLHVI EAINSFLRKS SSFQNEECST KRFFTGFLLI
410 420 430 440 450
VFLKILSPFV NWSYVCSIFA WCLLIYMHPR AHPKIISFFK TGTMGKEYKN
460 470 480 490 500
LKKREHQALN MIFDEQPETK FIEIFEIYKK ALLPNDWKFF RYSNRIFDPQ
510 520 530 540 550
DPYRRAQQFP PGVDSLADVI PPTGWSFDPN FEWKIDNDVD RWVVERGLNL
560 570
PITGEFLFDP MFKRRRLIHR VIKNATPVA
Length:579
Mass (Da):66,148
Last modified:February 1, 1995 - v1
Checksum:i2A6A73999C54C19E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10397 Genomic DNA Translation: AAB68980.1
BK006934 Genomic DNA Translation: DAA06843.1
PIRiS46757
RefSeqiNP_012020.1, NM_001179281.1

Genome annotation databases

EnsemblFungiiYHR150W; YHR150W; YHR150W
GeneIDi856555
KEGGisce:YHR150W

Similar proteinsi

Entry informationi

Entry nameiPEX28_YEAST
AccessioniPrimary (citable) accession number: P38848
Secondary accession number(s): D3DL99
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health