SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P38844

- DSE2_YEAST

UniProt

P38844 - DSE2_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Protein DSE2

Gene
DSE2, YHR143W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in pseudohyphal growth, cell wall metabolism and required for the separation of the mother and daughter cells.1 Publication

GO - Molecular functioni

  1. glucosidase activity Source: SGD

GO - Biological processi

  1. cytokinesis, completion of separation Source: SGD
  2. metabolic process Source: GOC
  3. pseudohyphal growth Source: SGD
Complete GO annotation...

Keywords - Biological processi

Cell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciYEAST:G3O-31180-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DSE2
Alternative name(s):
Daughter-specific expression protein 2
Gene namesi
Name:DSE2
Ordered Locus Names:YHR143W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR143w.
SGDiS000001186. DSE2.

Subcellular locationi

Secretedcell wall. Membrane; Lipid-anchorGPI-anchor
Note: GPI-anchored cell wall protein (GPI-CWP).1 Publication

GO - Cellular componenti

  1. anchored component of membrane Source: UniProtKB-KW
  2. extracellular region Source: SGD
  3. fungal-type cell wall Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed predictionAdd
BLAST
Chaini22 – 308287Protein DSE2PRO_0000014328Add
BLAST
Propeptidei309 – 32517Removed in mature form Reviewed predictionPRO_0000285355Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi308 – 3081GPI-anchor amidated aspartate Reviewed prediction

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Expressioni

Developmental stagei

Expressed in daughter cells.1 Publication

Inductioni

Expressed periodically during cell division. Requires ACE2, CBK1, MOB2 and SWI5. Expression is also increased under microgravity conditions.4 Publications

Gene expression databases

GenevestigatoriP38844.

Interactioni

Protein-protein interaction databases

BioGridi36576. 19 interactions.
IntActiP38844. 2 interactions.
MINTiMINT-7266789.
STRINGi4932.YHR143W.

Structurei

3D structure databases

ProteinModelPortaliP38844.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi72 – 281210Ser-richAdd
BLAST

Sequence similaritiesi

Belongs to the DSE2 family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG78578.
HOGENOMiHOG000000887.
OMAiTSTNTIY.
OrthoDBiEOG7XDBTT.

Family and domain databases

InterProiIPR026225. DSE2.
[Graphical view]
PRINTSiPR02066. DSEPROTEIN2.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38844-1 [UniParc]FASTAAdd to Basket

« Hide

MKFNFSTIFN ILFFLFTLIE ANSNGETVKL ITSDGIVYSY AVYTKTLAPA    50
RVVVKTISYT TTRVYPITLA NSVVSSTTEK ITEVSTVSAS EQVSATQTNS 100
LVSTSTVSTI SPTISSGSST SSSSTYDIES SQSIESSGTS SATAEPSASS 150
GFRLTSSSAF VSSTAPFSSQ LSSSSSSETS SSSFSTSSSS APLSLTSSSS 200
SSSSFATIIT LAPSSSKSGN SQLTLASSSS TSAVESSQTG STIARTTSTL 250
VPSSSVDTTS RATTSMPLES SSTQSISVSS SDGTCYVFYD DDDYYSTVYL 300
TNPSQSVDAA TTITSTNTIY ATVTI 325
Length:325
Mass (Da):33,417
Last modified:February 1, 1995 - v1
Checksum:i72FD171D5C919A1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10397 Genomic DNA. Translation: AAB68983.1.
BK006934 Genomic DNA. Translation: DAA06836.1.
PIRiS46760.
RefSeqiNP_012012.1. NM_001179274.1.

Genome annotation databases

EnsemblFungiiYHR143W; YHR143W; YHR143W.
GeneIDi856546.
KEGGisce:YHR143W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10397 Genomic DNA. Translation: AAB68983.1 .
BK006934 Genomic DNA. Translation: DAA06836.1 .
PIRi S46760.
RefSeqi NP_012012.1. NM_001179274.1.

3D structure databases

ProteinModelPortali P38844.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36576. 19 interactions.
IntActi P38844. 2 interactions.
MINTi MINT-7266789.
STRINGi 4932.YHR143W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YHR143W ; YHR143W ; YHR143W .
GeneIDi 856546.
KEGGi sce:YHR143W.

Organism-specific databases

CYGDi YHR143w.
SGDi S000001186. DSE2.

Phylogenomic databases

eggNOGi NOG78578.
HOGENOMi HOG000000887.
OMAi TSTNTIY.
OrthoDBi EOG7XDBTT.

Enzyme and pathway databases

BioCyci YEAST:G3O-31180-MONOMER.

Miscellaneous databases

NextBioi 982346.

Gene expression databases

Genevestigatori P38844.

Family and domain databases

InterProi IPR026225. DSE2.
[Graphical view ]
PRINTSi PR02066. DSEPROTEIN2.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates."
    Colman-Lerner A., Chin T.E., Brent R.
    Cell 107:739-750(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, DEVELOPMENTAL STAGE.
  4. "Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p."
    Doolin M.-T., Johnson A.L., Johnston L.H., Butler G.
    Mol. Microbiol. 40:422-432(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, FUNCTION.
  5. "Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae."
    Terashima H., Fukuchi S., Nakai K., Arisawa M., Hamada K., Yabuki N., Kitada K.
    Curr. Genet. 40:311-316(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. "Swm1p subunit of the APC/cyclosome is required for activation of the daughter-specific gene expression program mediated by Ace2p during growth at high temperature in Saccharomyces cerevisiae."
    Ufano S., Pablo M.E., Calzada A., del Rey F., Vazquez de Aldana C.R.
    J. Cell Sci. 117:545-557(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  8. "Effects of low-shear modeled microgravity on cell function, gene expression, and phenotype in Saccharomyces cerevisiae."
    Purevdorj-Gage B., Sheehan K.B., Hyman L.E.
    Appl. Environ. Microbiol. 72:4569-4575(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiDSE2_YEAST
AccessioniPrimary (citable) accession number: P38844
Secondary accession number(s): D3DL92
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 907 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi