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Protein

Protein DSE2

Gene

DSE2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in pseudohyphal growth, cell wall metabolism and required for the separation of the mother and daughter cells.1 Publication

Miscellaneous

Present with 907 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • glucosidase activity Source: SGD

GO - Biological processi

  • cell separation after cytokinesis Source: SGD
  • cell wall organization Source: UniProtKB-KW
  • pseudohyphal growth Source: SGD

Keywordsi

Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciYEAST:G3O-31180-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DSE2
Alternative name(s):
Daughter-specific expression protein 2
Gene namesi
Name:DSE2
Ordered Locus Names:YHR143W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR143W
SGDiS000001186 DSE2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000001432822 – 308Protein DSE2Add BLAST287
PropeptideiPRO_0000285355309 – 325Removed in mature formSequence analysisAdd BLAST17

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi308GPI-anchor amidated aspartateSequence analysis1

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDbiP38844
PRIDEiP38844

Expressioni

Developmental stagei

Expressed in daughter cells.1 Publication

Inductioni

Expressed periodically during cell division. Requires ACE2, CBK1, MOB2 and SWI5. Expression is also increased under microgravity conditions.4 Publications

Interactioni

Protein-protein interaction databases

BioGridi36576, 114 interactors
IntActiP38844, 2 interactors
MINTiP38844
STRINGi4932.YHR143W

Structurei

3D structure databases

ProteinModelPortaliP38844
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi72 – 281Ser-richAdd BLAST210

Sequence similaritiesi

Belongs to the DSE2 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000000887
InParanoidiP38844
OMAiTRVYPIT
OrthoDBiEOG092C5IWM

Family and domain databases

InterProiView protein in InterPro
IPR026225 DSE2
PRINTSiPR02066 DSEPROTEIN2

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38844-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFNFSTIFN ILFFLFTLIE ANSNGETVKL ITSDGIVYSY AVYTKTLAPA
60 70 80 90 100
RVVVKTISYT TTRVYPITLA NSVVSSTTEK ITEVSTVSAS EQVSATQTNS
110 120 130 140 150
LVSTSTVSTI SPTISSGSST SSSSTYDIES SQSIESSGTS SATAEPSASS
160 170 180 190 200
GFRLTSSSAF VSSTAPFSSQ LSSSSSSETS SSSFSTSSSS APLSLTSSSS
210 220 230 240 250
SSSSFATIIT LAPSSSKSGN SQLTLASSSS TSAVESSQTG STIARTTSTL
260 270 280 290 300
VPSSSVDTTS RATTSMPLES SSTQSISVSS SDGTCYVFYD DDDYYSTVYL
310 320
TNPSQSVDAA TTITSTNTIY ATVTI
Length:325
Mass (Da):33,417
Last modified:February 1, 1995 - v1
Checksum:i72FD171D5C919A1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10397 Genomic DNA Translation: AAB68983.1
BK006934 Genomic DNA Translation: DAA06836.1
PIRiS46760
RefSeqiNP_012012.1, NM_001179274.1

Genome annotation databases

EnsemblFungiiYHR143W; YHR143W; YHR143W
GeneIDi856546
KEGGisce:YHR143W

Similar proteinsi

Entry informationi

Entry nameiDSE2_YEAST
AccessioniPrimary (citable) accession number: P38844
Secondary accession number(s): D3DL92
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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