Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P38844

- DSE2_YEAST

UniProt

P38844 - DSE2_YEAST

Protein

Protein DSE2

Gene

DSE2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in pseudohyphal growth, cell wall metabolism and required for the separation of the mother and daughter cells.1 Publication

    GO - Molecular functioni

    1. glucosidase activity Source: SGD

    GO - Biological processi

    1. cytokinesis, completion of separation Source: SGD
    2. metabolic process Source: GOC
    3. pseudohyphal growth Source: SGD

    Keywords - Biological processi

    Cell wall biogenesis/degradation

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31180-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein DSE2
    Alternative name(s):
    Daughter-specific expression protein 2
    Gene namesi
    Name:DSE2
    Ordered Locus Names:YHR143W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHR143w.
    SGDiS000001186. DSE2.

    Subcellular locationi

    Secretedcell wall 1 Publication. Membrane 1 Publication; Lipid-anchorGPI-anchor 1 Publication
    Note: GPI-anchored cell wall protein (GPI-CWP).

    GO - Cellular componenti

    1. anchored component of membrane Source: UniProtKB-KW
    2. extracellular region Source: SGD
    3. fungal-type cell wall Source: SGD

    Keywords - Cellular componenti

    Cell wall, Membrane, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 308287Protein DSE2PRO_0000014328Add
    BLAST
    Propeptidei309 – 32517Removed in mature formSequence AnalysisPRO_0000285355Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi308 – 3081GPI-anchor amidated aspartateSequence Analysis

    Keywords - PTMi

    Glycoprotein, GPI-anchor, Lipoprotein

    Expressioni

    Developmental stagei

    Expressed in daughter cells.1 Publication

    Inductioni

    Expressed periodically during cell division. Requires ACE2, CBK1, MOB2 and SWI5. Expression is also increased under microgravity conditions.4 Publications

    Gene expression databases

    GenevestigatoriP38844.

    Interactioni

    Protein-protein interaction databases

    BioGridi36576. 19 interactions.
    IntActiP38844. 2 interactions.
    MINTiMINT-7266789.
    STRINGi4932.YHR143W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38844.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi72 – 281210Ser-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the DSE2 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG78578.
    HOGENOMiHOG000000887.
    OMAiTSTNTIY.
    OrthoDBiEOG7XDBTT.

    Family and domain databases

    InterProiIPR026225. DSE2.
    [Graphical view]
    PRINTSiPR02066. DSEPROTEIN2.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P38844-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFNFSTIFN ILFFLFTLIE ANSNGETVKL ITSDGIVYSY AVYTKTLAPA    50
    RVVVKTISYT TTRVYPITLA NSVVSSTTEK ITEVSTVSAS EQVSATQTNS 100
    LVSTSTVSTI SPTISSGSST SSSSTYDIES SQSIESSGTS SATAEPSASS 150
    GFRLTSSSAF VSSTAPFSSQ LSSSSSSETS SSSFSTSSSS APLSLTSSSS 200
    SSSSFATIIT LAPSSSKSGN SQLTLASSSS TSAVESSQTG STIARTTSTL 250
    VPSSSVDTTS RATTSMPLES SSTQSISVSS SDGTCYVFYD DDDYYSTVYL 300
    TNPSQSVDAA TTITSTNTIY ATVTI 325
    Length:325
    Mass (Da):33,417
    Last modified:February 1, 1995 - v1
    Checksum:i72FD171D5C919A1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10397 Genomic DNA. Translation: AAB68983.1.
    BK006934 Genomic DNA. Translation: DAA06836.1.
    PIRiS46760.
    RefSeqiNP_012012.1. NM_001179274.1.

    Genome annotation databases

    EnsemblFungiiYHR143W; YHR143W; YHR143W.
    GeneIDi856546.
    KEGGisce:YHR143W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10397 Genomic DNA. Translation: AAB68983.1 .
    BK006934 Genomic DNA. Translation: DAA06836.1 .
    PIRi S46760.
    RefSeqi NP_012012.1. NM_001179274.1.

    3D structure databases

    ProteinModelPortali P38844.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36576. 19 interactions.
    IntActi P38844. 2 interactions.
    MINTi MINT-7266789.
    STRINGi 4932.YHR143W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHR143W ; YHR143W ; YHR143W .
    GeneIDi 856546.
    KEGGi sce:YHR143W.

    Organism-specific databases

    CYGDi YHR143w.
    SGDi S000001186. DSE2.

    Phylogenomic databases

    eggNOGi NOG78578.
    HOGENOMi HOG000000887.
    OMAi TSTNTIY.
    OrthoDBi EOG7XDBTT.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31180-MONOMER.

    Miscellaneous databases

    NextBioi 982346.

    Gene expression databases

    Genevestigatori P38844.

    Family and domain databases

    InterProi IPR026225. DSE2.
    [Graphical view ]
    PRINTSi PR02066. DSEPROTEIN2.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates."
      Colman-Lerner A., Chin T.E., Brent R.
      Cell 107:739-750(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, DEVELOPMENTAL STAGE.
    4. "Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p."
      Doolin M.-T., Johnson A.L., Johnston L.H., Butler G.
      Mol. Microbiol. 40:422-432(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, FUNCTION.
    5. "Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae."
      Terashima H., Fukuchi S., Nakai K., Arisawa M., Hamada K., Yabuki N., Kitada K.
      Curr. Genet. 40:311-316(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "Swm1p subunit of the APC/cyclosome is required for activation of the daughter-specific gene expression program mediated by Ace2p during growth at high temperature in Saccharomyces cerevisiae."
      Ufano S., Pablo M.E., Calzada A., del Rey F., Vazquez de Aldana C.R.
      J. Cell Sci. 117:545-557(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.
    8. "Effects of low-shear modeled microgravity on cell function, gene expression, and phenotype in Saccharomyces cerevisiae."
      Purevdorj-Gage B., Sheehan K.B., Hyman L.E.
      Appl. Environ. Microbiol. 72:4569-4575(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.

    Entry informationi

    Entry nameiDSE2_YEAST
    AccessioniPrimary (citable) accession number: P38844
    Secondary accession number(s): D3DL92
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 907 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3