P38841 (YHT8_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YHR138C

Gene names

Ordered Locus Names:

YHR138C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	114 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	Present with 319 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the protease inhibitor I9 family. [View classification]

Ontologies

Keywords
Domain	Signal
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	vacuole fusion, non-autophagic Inferred from genetic interaction PubMed 9657146. Source: SGD
Molecular_function	endopeptidase inhibitor activity Inferred from genetic interaction PubMed 9657146. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
YHR080C	P38800	1	EBI-24748,EBI-24597

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 114	95	Uncharacterized protein YHR138C		PRO_0000026706
Amino acid modifications
	Modified residue	37	1	Phosphothreonine Ref.6
	Modified residue	41	1	Phosphoserine Ref.6

Sequences

	Sequence		Length	Mass (Da)
	P38841 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: FF168CA45F2EE417	FASTA	114	12,753
	10 20 30 40 50 60 MKASYLVLIF ISIFSMAQAS SLSSYIVTFP KTDNMATDQN SIIEDVKKYV VDIGGKITHE 70 80 90 100 110 YSLIKGFTVD LPDSDQILDG LKERLSYIES EYGAKCNLEK DSEVHALNRD HLVA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	Houssaini I.I., Vissers S., Cartiaux M., Urrestarazu A. Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Sigma 1278B.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-37 AND SER-41, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U10398 Genomic DNA. Translation: AAB68418.1. Y13625 Genomic DNA. Translation: CAA73951.1. AY557846 Genomic DNA. Translation: AAS56172.1. BK006934 Genomic DNA. Translation: DAA06831.1.
PIR	S48982.
RefSeq	NP_012006.1. NM_001179268.1.
3D structure databases
ProteinModelPortal	P38841.
SMR	P38841. Positions 22-107.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4718N.
MINT	MINT-573166.
STRING	4932.YHR138C.
Proteomic databases
PaxDb	P38841.
PeptideAtlas	P38841.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHR138C; YHR138C; YHR138C.
GeneID	856540.
KEGG	sce:YHR138C.
Organism-specific databases
CYGD	YHR138c.
SGD	S000001180. YHR138C.
Phylogenomic databases
eggNOG	NOG245535.
HOGENOM	HOG000165553.
OrthoDB	EOG43JGFM.
Gene expression databases
Genevestigator	P38841.
GermOnline	YHR138C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR009020. Prot_inh_propept. [Graphical view]
SUPFAM	SSF54897. Prot_inh_propept. 1 hit.
ProtoNet	Search...
Other
NextBio	982331.

Entry information

Entry name

YHT8_YEAST

Accession

Primary (citable) accession number: P38841
Secondary accession number(s): D3DL87

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program