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P38835 (YHT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PH domain-containing protein YHR131C
Gene names
Ordered Locus Names:YHR131C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length850 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Ref.5.

Miscellaneous

Present with 172 molecules/cell in log phase SD medium.

Sequence similarities

Contains 1 PH domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

RSP5P399403EBI-24724,EBI-16219

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 850850PH domain-containing protein YHR131C
PRO_0000202917

Regions

Domain194 – 306113PH
Compositional bias318 – 33922Arg-rich
Compositional bias796 – 84550Asp-rich

Sequences

Sequence LengthMass (Da)Tools
P38835 [UniParc].

Last modified September 27, 2005. Version 2.
Checksum: DD63F340A8C736DB

FASTA85096,099
        10         20         30         40         50         60 
MALPIEGKLS MANNRIERLK SPSSSSTCSM DEVLITSSNN SSSICLETMR QLPREGVSGQ 

        70         80         90        100        110        120 
INIIKETAAS SSSHAALFIK QDLYEHIDPL PAYPPSYDLV NPNKEVRFPI FGDTAPCPKS 

       130        140        150        160        170        180 
SLPPLYAPAV YELTLISLKL ERLSPYEISS NRSWRNFIIE INSTQLNFYH IDESLTKHIR 

       190        200        210        220        230        240 
NYSSGETKSE KEDRIHSDLV HRSDQSQHLH HRLFTLPTRS ASEFKKADQE RISYRVKRDR 

       250        260        270        280        290        300 
SRYLTDEALY KSFTLQNARF GIPTDYTKKS FVLRMSCESE QFLLRFSHID DMIDWSMYLS 

       310        320        330        340        350        360 
IGISVSLDLE VREYPDYRIV PRRRRRRRRR RRRRRHTHRS ESSMGSFSQR FIRSNSRPDL 

       370        380        390        400        410        420 
IQRYSTGSST NNNTTIRERS NTFTAGLLDH YCTGLSKTPT EALISSAASG ESSDNSTLGS 

       430        440        450        460        470        480 
TRSLSGCSAS RSIASRSLKF KIKNFFRPKN SSRTEKLHRL RSNSSNLNSV IETEEDDEHH 

       490        500        510        520        530        540 
ESSGGDHPEP GVPVNTTIKV ERPMHRNRAI SMPQRQSLRR AISEEVVPIK FPNSTVGESV 

       550        560        570        580        590        600 
HSPSPIEHLS VDGCEIMLQS QNAVMKEELR SVASNLVANE RDEASIRPKP QSSSIYLSGL 

       610        620        630        640        650        660 
APNGESATDL SQSSRSLCLT NRDAEINDDE SATETDEDEN DGETDEYAGD DTNDDTDDSN 

       670        680        690        700        710        720 
IGYAYGSESD YSCLIEERIR NRRRASSTLS CFSNIPYGTD DIKWKPAIKE ISRRRYLRDS 

       730        740        750        760        770        780 
LKCIKPFLDS NDCLGKVIYI PVSGPTFETS NKIHFSNRQS LQKQKNHFLK GFIVGPTALI 

       790        800        810        820        830        840 
ELNCKNKNAI VGTTKDAEDH GEDDGDGDDG EDDDDDDDDD DDDDDDEDDD DDDDDDDDDD 

       850 
DDDDDGQITA 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Hong E.L., Cherry J.M.
Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION TO N-TERMINUS.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Sequencing and comparison of yeast species to identify genes and regulatory elements."
Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION OF FRAMESHIFT.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U10398 Genomic DNA. Translation: AAB68414.2.
BK006934 Genomic DNA. Translation: DAA06823.1.
PIRS48975.
RefSeqNP_011999.2. NM_001179261.1.

3D structure databases

ProteinModelPortalP38835.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36563. 17 interactions.
IntActP38835. 15 interactions.
MINTMINT-2492416.
STRING4932.YHR131C.

Proteomic databases

PaxDbP38835.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR131C; YHR131C; YHR131C.
GeneID856532.
KEGGsce:YHR131C.

Organism-specific databases

CYGDYHR131c.
SGDS000001173. YHR131C.

Phylogenomic databases

eggNOGNOG44985.
GeneTreeENSGT00700000105416.
OMANDDESAT.
OrthoDBEOG7MPRT6.

Enzyme and pathway databases

BioCycYEAST:G3O-31169-MONOMER.

Gene expression databases

GenevestigatorP38835.

Family and domain databases

Gene3D2.30.29.30. 2 hits.
InterProIPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
[Graphical view]
SMARTSM00233. PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982307.

Entry information

Entry nameYHT1_YEAST
AccessionPrimary (citable) accession number: P38835
Secondary accession number(s): D3DL79
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: September 27, 2005
Last modified: February 19, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families