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P38835

- YHT1_YEAST

UniProt

P38835 - YHT1_YEAST

Protein

PH domain-containing protein YHR131C

Gene

YHR131C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 2 (27 Sep 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31169-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PH domain-containing protein YHR131C
    Gene namesi
    Ordered Locus Names:YHR131C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHR131c.
    SGDiS000001173. YHR131C.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 850850PH domain-containing protein YHR131CPRO_0000202917Add
    BLAST

    Proteomic databases

    PaxDbiP38835.

    Expressioni

    Gene expression databases

    GenevestigatoriP38835.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    RSP5P399403EBI-24724,EBI-16219

    Protein-protein interaction databases

    BioGridi36563. 18 interactions.
    IntActiP38835. 15 interactions.
    MINTiMINT-2492416.
    STRINGi4932.YHR131C.

    Structurei

    3D structure databases

    ProteinModelPortaliP38835.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini194 – 306113PHAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi318 – 33922Arg-richAdd
    BLAST
    Compositional biasi796 – 84550Asp-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PH domain.Curated

    Phylogenomic databases

    eggNOGiNOG44985.
    GeneTreeiENSGT00700000105416.
    OMAiNDDESAT.
    OrthoDBiEOG7MPRT6.

    Family and domain databases

    Gene3Di2.30.29.30. 2 hits.
    InterProiIPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view]
    SMARTiSM00233. PH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P38835-1 [UniParc]FASTAAdd to Basket

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    MALPIEGKLS MANNRIERLK SPSSSSTCSM DEVLITSSNN SSSICLETMR    50
    QLPREGVSGQ INIIKETAAS SSSHAALFIK QDLYEHIDPL PAYPPSYDLV 100
    NPNKEVRFPI FGDTAPCPKS SLPPLYAPAV YELTLISLKL ERLSPYEISS 150
    NRSWRNFIIE INSTQLNFYH IDESLTKHIR NYSSGETKSE KEDRIHSDLV 200
    HRSDQSQHLH HRLFTLPTRS ASEFKKADQE RISYRVKRDR SRYLTDEALY 250
    KSFTLQNARF GIPTDYTKKS FVLRMSCESE QFLLRFSHID DMIDWSMYLS 300
    IGISVSLDLE VREYPDYRIV PRRRRRRRRR RRRRRHTHRS ESSMGSFSQR 350
    FIRSNSRPDL IQRYSTGSST NNNTTIRERS NTFTAGLLDH YCTGLSKTPT 400
    EALISSAASG ESSDNSTLGS TRSLSGCSAS RSIASRSLKF KIKNFFRPKN 450
    SSRTEKLHRL RSNSSNLNSV IETEEDDEHH ESSGGDHPEP GVPVNTTIKV 500
    ERPMHRNRAI SMPQRQSLRR AISEEVVPIK FPNSTVGESV HSPSPIEHLS 550
    VDGCEIMLQS QNAVMKEELR SVASNLVANE RDEASIRPKP QSSSIYLSGL 600
    APNGESATDL SQSSRSLCLT NRDAEINDDE SATETDEDEN DGETDEYAGD 650
    DTNDDTDDSN IGYAYGSESD YSCLIEERIR NRRRASSTLS CFSNIPYGTD 700
    DIKWKPAIKE ISRRRYLRDS LKCIKPFLDS NDCLGKVIYI PVSGPTFETS 750
    NKIHFSNRQS LQKQKNHFLK GFIVGPTALI ELNCKNKNAI VGTTKDAEDH 800
    GEDDGDGDDG EDDDDDDDDD DDDDDDEDDD DDDDDDDDDD DDDDDGQITA 850
    Length:850
    Mass (Da):96,099
    Last modified:September 27, 2005 - v2
    Checksum:iDD63F340A8C736DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10398 Genomic DNA. Translation: AAB68414.2.
    BK006934 Genomic DNA. Translation: DAA06823.1.
    PIRiS48975.
    RefSeqiNP_011999.2. NM_001179261.1.

    Genome annotation databases

    EnsemblFungiiYHR131C; YHR131C; YHR131C.
    GeneIDi856532.
    KEGGisce:YHR131C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10398 Genomic DNA. Translation: AAB68414.2 .
    BK006934 Genomic DNA. Translation: DAA06823.1 .
    PIRi S48975.
    RefSeqi NP_011999.2. NM_001179261.1.

    3D structure databases

    ProteinModelPortali P38835.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36563. 18 interactions.
    IntActi P38835. 15 interactions.
    MINTi MINT-2492416.
    STRINGi 4932.YHR131C.

    Proteomic databases

    PaxDbi P38835.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHR131C ; YHR131C ; YHR131C .
    GeneIDi 856532.
    KEGGi sce:YHR131C.

    Organism-specific databases

    CYGDi YHR131c.
    SGDi S000001173. YHR131C.

    Phylogenomic databases

    eggNOGi NOG44985.
    GeneTreei ENSGT00700000105416.
    OMAi NDDESAT.
    OrthoDBi EOG7MPRT6.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31169-MONOMER.

    Miscellaneous databases

    NextBioi 982307.

    Gene expression databases

    Genevestigatori P38835.

    Family and domain databases

    Gene3Di 2.30.29.30. 2 hits.
    InterProi IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view ]
    SMARTi SM00233. PH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Hong E.L., Cherry J.M.
      Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION TO N-TERMINUS.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
      Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
      Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF FRAMESHIFT.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiYHT1_YEAST
    AccessioniPrimary (citable) accession number: P38835
    Secondary accession number(s): D3DL79
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: September 27, 2005
    Last modified: October 1, 2014
    This is version 95 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 172 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3