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Protein

PH domain-containing protein YHR131C

Gene

YHR131C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31169-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
PH domain-containing protein YHR131C
Gene namesi
Ordered Locus Names:YHR131C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR131c.
SGDiS000001173. YHR131C.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 850850PH domain-containing protein YHR131CPRO_0000202917Add
BLAST

Proteomic databases

PaxDbiP38835.

Expressioni

Gene expression databases

GenevestigatoriP38835.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RSP5P399403EBI-24724,EBI-16219

Protein-protein interaction databases

BioGridi36563. 19 interactions.
IntActiP38835. 15 interactions.
MINTiMINT-2492416.
STRINGi4932.YHR131C.

Structurei

3D structure databases

ProteinModelPortaliP38835.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini194 – 306113PHAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi318 – 33922Arg-richAdd
BLAST
Compositional biasi796 – 84550Asp-richAdd
BLAST

Sequence similaritiesi

Contains 1 PH domain.Curated

Phylogenomic databases

eggNOGiNOG44985.
GeneTreeiENSGT00700000105416.
InParanoidiP38835.
OMAiNDDESAT.
OrthoDBiEOG7MPRT6.

Family and domain databases

Gene3Di2.30.29.30. 2 hits.
InterProiIPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPIEGKLS MANNRIERLK SPSSSSTCSM DEVLITSSNN SSSICLETMR
60 70 80 90 100
QLPREGVSGQ INIIKETAAS SSSHAALFIK QDLYEHIDPL PAYPPSYDLV
110 120 130 140 150
NPNKEVRFPI FGDTAPCPKS SLPPLYAPAV YELTLISLKL ERLSPYEISS
160 170 180 190 200
NRSWRNFIIE INSTQLNFYH IDESLTKHIR NYSSGETKSE KEDRIHSDLV
210 220 230 240 250
HRSDQSQHLH HRLFTLPTRS ASEFKKADQE RISYRVKRDR SRYLTDEALY
260 270 280 290 300
KSFTLQNARF GIPTDYTKKS FVLRMSCESE QFLLRFSHID DMIDWSMYLS
310 320 330 340 350
IGISVSLDLE VREYPDYRIV PRRRRRRRRR RRRRRHTHRS ESSMGSFSQR
360 370 380 390 400
FIRSNSRPDL IQRYSTGSST NNNTTIRERS NTFTAGLLDH YCTGLSKTPT
410 420 430 440 450
EALISSAASG ESSDNSTLGS TRSLSGCSAS RSIASRSLKF KIKNFFRPKN
460 470 480 490 500
SSRTEKLHRL RSNSSNLNSV IETEEDDEHH ESSGGDHPEP GVPVNTTIKV
510 520 530 540 550
ERPMHRNRAI SMPQRQSLRR AISEEVVPIK FPNSTVGESV HSPSPIEHLS
560 570 580 590 600
VDGCEIMLQS QNAVMKEELR SVASNLVANE RDEASIRPKP QSSSIYLSGL
610 620 630 640 650
APNGESATDL SQSSRSLCLT NRDAEINDDE SATETDEDEN DGETDEYAGD
660 670 680 690 700
DTNDDTDDSN IGYAYGSESD YSCLIEERIR NRRRASSTLS CFSNIPYGTD
710 720 730 740 750
DIKWKPAIKE ISRRRYLRDS LKCIKPFLDS NDCLGKVIYI PVSGPTFETS
760 770 780 790 800
NKIHFSNRQS LQKQKNHFLK GFIVGPTALI ELNCKNKNAI VGTTKDAEDH
810 820 830 840 850
GEDDGDGDDG EDDDDDDDDD DDDDDDEDDD DDDDDDDDDD DDDDDGQITA
Length:850
Mass (Da):96,099
Last modified:September 27, 2005 - v2
Checksum:iDD63F340A8C736DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10398 Genomic DNA. Translation: AAB68414.2.
BK006934 Genomic DNA. Translation: DAA06823.1.
PIRiS48975.
RefSeqiNP_011999.2. NM_001179261.1.

Genome annotation databases

EnsemblFungiiYHR131C; YHR131C; YHR131C.
GeneIDi856532.
KEGGisce:YHR131C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10398 Genomic DNA. Translation: AAB68414.2.
BK006934 Genomic DNA. Translation: DAA06823.1.
PIRiS48975.
RefSeqiNP_011999.2. NM_001179261.1.

3D structure databases

ProteinModelPortaliP38835.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36563. 19 interactions.
IntActiP38835. 15 interactions.
MINTiMINT-2492416.
STRINGi4932.YHR131C.

Proteomic databases

PaxDbiP38835.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR131C; YHR131C; YHR131C.
GeneIDi856532.
KEGGisce:YHR131C.

Organism-specific databases

CYGDiYHR131c.
SGDiS000001173. YHR131C.

Phylogenomic databases

eggNOGiNOG44985.
GeneTreeiENSGT00700000105416.
InParanoidiP38835.
OMAiNDDESAT.
OrthoDBiEOG7MPRT6.

Enzyme and pathway databases

BioCyciYEAST:G3O-31169-MONOMER.

Miscellaneous databases

NextBioi982307.

Gene expression databases

GenevestigatoriP38835.

Family and domain databases

Gene3Di2.30.29.30. 2 hits.
InterProiIPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Hong E.L., Cherry J.M.
    Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO N-TERMINUS.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
    Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
    Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF FRAMESHIFT.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYHT1_YEAST
AccessioniPrimary (citable) accession number: P38835
Secondary accession number(s): D3DL79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: September 27, 2005
Last modified: January 7, 2015
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 172 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.