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Protein

Probable GPI-anchored protein ANS1

Gene

ANS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. structural constituent of cell wall Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31166-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable GPI-anchored protein ANS1
Gene namesi
Name:ANS1
Ordered Locus Names:YHR126C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR126c.
SGDiS000001168. ANS1.

Subcellular locationi

GO - Cellular componenti

  1. anchored component of membrane Source: UniProtKB-KW
  2. cell wall Source: InterPro
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 137117Probable GPI-anchored protein ANS1PRO_0000203777Add
BLAST
Propeptidei138 – 15922Removed in mature formSequence AnalysisPRO_0000402190Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi137 – 1371GPI-anchor amidated glycineSequence Analysis

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Expressioni

Inductioni

Expression is regulated by AZF1.1 Publication

Gene expression databases

GenevestigatoriP38832.

Interactioni

Protein-protein interaction databases

BioGridi36559. 3 interactions.
STRINGi4932.YHR126C.

Structurei

3D structure databases

ProteinModelPortaliP38832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati101 – 11414PIR1/2/3Add
BLAST

Sequence similaritiesi

Contains 1 PIR1/2/3 repeat.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG718KQZ.

Family and domain databases

InterProiIPR000420. Yeast_PIR.
[Graphical view]
PfamiPF00399. PIR. 1 hit.
[Graphical view]
PROSITEiPS00929. PIR_REPEAT_1. 1 hit.
PS50256. PIR_REPEAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCTLVSTLF AITNILVAHA QVSNSSDTLD VQFANSTNSY IEGKFNSTDE
60 70 80 90 100
AFNSSASWSL AAQQKKISNA AVYDVGGWNG SLYRSNRSAV ADHQPGKKQD
110 120 130 140 150
AAISQISDGQ IQATASGPET TAATTPSSTA NVSVYEGAGM KVESKNMGYI

VGVAALLFL
Length:159
Mass (Da):16,635
Last modified:February 1, 1995 - v1
Checksum:iEFF6F5F5A6DEA211
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10398 Genomic DNA. Translation: AAB68411.1.
AY692674 Genomic DNA. Translation: AAT92693.1.
BK006934 Genomic DNA. Translation: DAA06819.1.
PIRiS48970.
RefSeqiNP_011994.1. NM_001179256.1.

Genome annotation databases

EnsemblFungiiYHR126C; YHR126C; YHR126C.
GeneIDi856527.
KEGGisce:YHR126C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10398 Genomic DNA. Translation: AAB68411.1.
AY692674 Genomic DNA. Translation: AAT92693.1.
BK006934 Genomic DNA. Translation: DAA06819.1.
PIRiS48970.
RefSeqiNP_011994.1. NM_001179256.1.

3D structure databases

ProteinModelPortaliP38832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36559. 3 interactions.
STRINGi4932.YHR126C.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR126C; YHR126C; YHR126C.
GeneIDi856527.
KEGGisce:YHR126C.

Organism-specific databases

CYGDiYHR126c.
SGDiS000001168. ANS1.

Phylogenomic databases

OrthoDBiEOG718KQZ.

Enzyme and pathway databases

BioCyciYEAST:G3O-31166-MONOMER.

Miscellaneous databases

NextBioi982295.

Gene expression databases

GenevestigatoriP38832.

Family and domain databases

InterProiIPR000420. Yeast_PIR.
[Graphical view]
PfamiPF00399. PIR. 1 hit.
[Graphical view]
PROSITEiPS00929. PIR_REPEAT_1. 1 hit.
PS50256. PIR_REPEAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "The function and properties of the Azf1 transcriptional regulator change with growth conditions in Saccharomyces cerevisiae."
    Slattery M.G., Liko D., Heideman W.
    Eukaryot. Cell 5:313-320(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiANS1_YEAST
AccessioniPrimary (citable) accession number: P38832
Secondary accession number(s): D3DL75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.