Reviewed,
UniProtKB/Swiss-Prot P38822 (BZZ1_YEAST)
Last modified
June 16, 2009.
Version 79.
History...
Clusters with 100%,
90%,
50% identity |
Documents (4) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Protein BZZ1 | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 633 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subunit structure | Associates with BEE1. |
| Miscellaneous | Present with 5440 molecules/cell in log phase SD medium. Ref.2 |
| Sequence similarities | Contains 1 FCH domain. Contains 2 SH3 domains. |
Ontologies
| Keywords | |
|---|---|
| Domain | Coiled coil Repeat SH3 domain |
| PTM | Phosphoprotein |
| Technical term | 3D-structure Complete proteome |
| Gene Ontology (GO) | |
| Biological process | actin filament organization Inferred from physical interaction. Source: SGD endocytosisInferred from genetic interaction. Source: SGD response to salt stressInferred from genetic interaction. Source: SGD |
| Cellular component | actin cortical patch Inferred from direct assay. Source: SGD mating projection tipInferred from direct assay. Source: SGD |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Binary interactions
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||||||||||||||||
Molecule processing | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 633 | 633 | Protein BZZ1 | PRO_0000065033 | |||||||||||||||||||||
Regions | |||||||||||||||||||||||||
| Domain | 5 – 68 | 64 | FCH | ||||||||||||||||||||||
| Domain | 493 – 555 | 63 | SH3 1 | ||||||||||||||||||||||
| Domain | 577 – 633 | 57 | SH3 2 | ||||||||||||||||||||||
| Coiled coil | 138 – 210 | 73 | Potential | ||||||||||||||||||||||
Amino acid modifications | |||||||||||||||||||||||||
| Modified residue | 327 | 1 | Phosphoserine Ref.4 | ||||||||||||||||||||||
| Modified residue | 463 | 1 | Phosphoserine Ref.4 | ||||||||||||||||||||||
| Modified residue | 472 | 1 | Phosphoserine Ref.4 | ||||||||||||||||||||||
| Modified residue | 476 | 1 | Phosphoserine Ref.4 | ||||||||||||||||||||||
| Modified residue | 576 | 1 | Phosphothreonine Ref.3 | ||||||||||||||||||||||
Secondary structure | |||||||||||||||||||||||||
Helix Strand Turn | |||||||||||||||||||||||||
| Beta strand | 520 – 524 | 5 | |||||||||||||||||||||||
| Beta strand | 527 – 536 | 10 | |||||||||||||||||||||||
| Turn | 537 – 540 | 4 | |||||||||||||||||||||||
| Beta strand | 541 – 546 | 6 | |||||||||||||||||||||||
| Helix | 547 – 549 | 3 | |||||||||||||||||||||||
| Beta strand | 582 – 584 | 3 | |||||||||||||||||||||||
| Beta strand | 603 – 608 | 6 | |||||||||||||||||||||||
| Beta strand | 612 – 620 | 9 | |||||||||||||||||||||||
| Beta strand | 623 – 628 | 6 | |||||||||||||||||||||||
| Helix | 629 – 631 | 3 | |||||||||||||||||||||||
Sequences
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References
| [1] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. Vaudin M.Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [2] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [3] | "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-576, MASS SPECTROMETRY. |
| [4] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-327; SER-463; SER-472 AND SER-476, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| U00059 Genomic DNA. Translation: AAB68850.1. | |||||||||||||||||||
| PIR | S48956. | ||||||||||||||||||
| RefSeq | NP_011982.1. | ||||||||||||||||||
3D structure databases | |||||||||||||||||||
| |||||||||||||||||||
| ModBase | Search... | ||||||||||||||||||
Protein-protein interaction databases | |||||||||||||||||||
| DIP | DIP:2143N. | ||||||||||||||||||
| IntAct | P38822. 139 interactions. | ||||||||||||||||||
Genome annotation databases | |||||||||||||||||||
| Ensembl | YHR114W. Saccharomyces cerevisiae. [Contig view] | ||||||||||||||||||
| GeneID | 856514. | ||||||||||||||||||
| GenomeReviews | Gene locus YHR114W in contig U00093_GR. | ||||||||||||||||||
| KEGG | sce:YHR114W. | ||||||||||||||||||
| NMPDR | fig|4932.3.peg.3143. | ||||||||||||||||||
Organism-specific databases | |||||||||||||||||||
| CYGD | YHR114w. | ||||||||||||||||||
| SGD | S000001156. BZZ1. | ||||||||||||||||||
| Yeast-GFP | Search... | ||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||
| HOGENOM | P38822. | ||||||||||||||||||
| OMA | P38822. GVAVETW. | ||||||||||||||||||
Gene expression databases | |||||||||||||||||||
| GermOnline | YHR114W. Saccharomyces cerevisiae. | ||||||||||||||||||
Family and domain databases | |||||||||||||||||||
| InterPro | IPR001060. FCH. IPR001452. SH3_domain. [Graphical view] | ||||||||||||||||||
| Pfam | PF00611. FCH. 1 hit. PF00018. SH3_1. 2 hits. [Graphical view] | ||||||||||||||||||
| ProDom | PD000066. SH3. 2 hits. [Graphical view] [Entries sharing at least one domain] | ||||||||||||||||||
| SMART | SM00055. FCH. 1 hit. SM00326. SH3. 2 hits. [Graphical view] | ||||||||||||||||||
| PROSITE | PS50133. FCH. 1 hit. PS50002. SH3. 2 hits. [Graphical view] | ||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||
Other Resources | |||||||||||||||||||
| NextBio | 982260. | ||||||||||||||||||
Entry information
| Entry name | BZZ1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P38822 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome VIII Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names |

Clusters with


