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P38804 (SDO1L_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Restriction of telomere capping protein 3
Gene names
Name:RTC3
Ordered Locus Names:YHR087W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length111 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May play a role in RNA metabolism, rRNA-processing, and in a process influencing telomere capping. Ref.6

Subcellular location

Cytoplasm. Nucleus Ref.4.

Miscellaneous

Present with 2430 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the SDO1-like family.

Ontologies

Keywords
   Biological processRibosome biogenesis
rRNA processing
   Cellular componentCytoplasm
Nucleus
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processRNA metabolic process

Inferred from genetic interaction Ref.8. Source: SGD

rRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 111111Restriction of telomere capping protein 3
PRO_0000202905

Secondary structure

................... 111
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P38804 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 34A95645CAFB51BD

FASTA11112,009
        10         20         30         40         50         60 
MSTVTKYFYK GENTDLIVFA ASEELVDEYL KNPSIGKLSE VVELFEVFTP QDGRGAEGEL 

        70         80         90        100        110 
GAASKAQVEN EFGKGKKIEE VIDLILRNGK PNSTTSSLKT KGGNAGTKAY N 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae."
Addinall S.G., Downey M., Yu M., Zubko M.K., Dewar J., Leake A., Hallinan J., Shaw O., James K., Wilkinson D.J., Wipat A., Durocher D., Lydall D.
Genetics 180:2251-2266(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[7]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism."
Savchenko A., Krogan N., Cort J.R., Evdokimova E., Lew J.M., Yee A.A., Sanchez-Pulido L., Andrade M.A., Bochkarev A., Watson J.D., Kennedy M.A., Greenblatt J., Hughes T., Arrowsmith C.H., Rommens J.M., Edwards A.M.
J. Biol. Chem. 280:19213-19220(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00060 Genomic DNA. Translation: AAB68927.1.
AY557845 Genomic DNA. Translation: AAS56171.1.
BK006934 Genomic DNA. Translation: DAA06783.1.
PIRS46719.
RefSeqNP_011955.1. NM_001179217.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1NYNNMR-A1-111[»]
ProteinModelPortalP38804.
SMRP38804. Positions 1-111.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36522. 83 interactions.
DIPDIP-2925N.
IntActP38804. 1 interaction.
MINTMINT-558198.
STRING4932.YHR087W.

Proteomic databases

MaxQBP38804.
PaxDbP38804.
PeptideAtlasP38804.

Protocols and materials databases

DNASU856487.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR087W; YHR087W; YHR087W.
GeneID856487.
KEGGsce:YHR087W.

Organism-specific databases

CYGDYHR087w.
SGDS000001129. RTC3.

Phylogenomic databases

eggNOGNOG81974.
HOGENOMHOG000216667.
OMAGEIHEAS.
OrthoDBEOG75J117.

Enzyme and pathway databases

BioCycYEAST:G3O-31134-MONOMER.

Gene expression databases

GenevestigatorP38804.

Family and domain databases

Gene3D3.30.1250.10. 1 hit.
InterProIPR019783. Ribosome_mat_SBDS_N.
[Graphical view]
PfamPF01172. SBDS. 1 hit.
[Graphical view]
SUPFAMSSF89895. SSF89895. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP38804.
NextBio982185.

Entry information

Entry nameSDO1L_YEAST
AccessionPrimary (citable) accession number: P38804
Secondary accession number(s): D3DL39
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 9, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references