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Protein

Restriction of telomere capping protein 3

Gene

RTC3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in RNA metabolism, rRNA-processing, and in a process influencing telomere capping.1 Publication

GO - Biological processi

  1. RNA metabolic process Source: SGD
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-31134-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Restriction of telomere capping protein 3
Gene namesi
Name:RTC3
Ordered Locus Names:YHR087W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR087w.
SGDiS000001129. RTC3.

Subcellular locationi

Cytoplasm 1 Publication. Nucleus 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 111111Restriction of telomere capping protein 3PRO_0000202905Add
BLAST

Proteomic databases

MaxQBiP38804.
PaxDbiP38804.
PeptideAtlasiP38804.

Expressioni

Gene expression databases

GenevestigatoriP38804.

Interactioni

Protein-protein interaction databases

BioGridi36522. 83 interactions.
DIPiDIP-2925N.
IntActiP38804. 1 interaction.
MINTiMINT-558198.
STRINGi4932.YHR087W.

Structurei

Secondary structure

1
111
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 106Combined sources
Beta strandi12 – 2110Combined sources
Helixi23 – 319Combined sources
Helixi35 – 417Combined sources
Beta strandi52 – 543Combined sources
Beta strandi56 – 583Combined sources
Helixi65 – 728Combined sources
Helixi79 – 879Combined sources
Beta strandi107 – 1093Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NYNNMR-A1-111[»]
ProteinModelPortaliP38804.
SMRiP38804. Positions 1-111.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP38804.

Family & Domainsi

Sequence similaritiesi

Belongs to the SDO1-like family.Curated

Phylogenomic databases

eggNOGiNOG81974.
HOGENOMiHOG000216667.
InParanoidiP38804.
OMAiTEGEIHE.
OrthoDBiEOG75J117.

Family and domain databases

Gene3Di3.30.1250.10. 1 hit.
InterProiIPR019783. Ribosome_mat_SBDS_N.
[Graphical view]
PfamiPF01172. SBDS. 1 hit.
[Graphical view]
SUPFAMiSSF89895. SSF89895. 1 hit.

Sequencei

Sequence statusi: Complete.

P38804-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTVTKYFYK GENTDLIVFA ASEELVDEYL KNPSIGKLSE VVELFEVFTP
60 70 80 90 100
QDGRGAEGEL GAASKAQVEN EFGKGKKIEE VIDLILRNGK PNSTTSSLKT
110
KGGNAGTKAY N
Length:111
Mass (Da):12,009
Last modified:February 1, 1995 - v1
Checksum:i34A95645CAFB51BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00060 Genomic DNA. Translation: AAB68927.1.
AY557845 Genomic DNA. Translation: AAS56171.1.
BK006934 Genomic DNA. Translation: DAA06783.1.
PIRiS46719.
RefSeqiNP_011955.1. NM_001179217.1.

Genome annotation databases

EnsemblFungiiYHR087W; YHR087W; YHR087W.
GeneIDi856487.
KEGGisce:YHR087W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00060 Genomic DNA. Translation: AAB68927.1.
AY557845 Genomic DNA. Translation: AAS56171.1.
BK006934 Genomic DNA. Translation: DAA06783.1.
PIRiS46719.
RefSeqiNP_011955.1. NM_001179217.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NYNNMR-A1-111[»]
ProteinModelPortaliP38804.
SMRiP38804. Positions 1-111.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36522. 83 interactions.
DIPiDIP-2925N.
IntActiP38804. 1 interaction.
MINTiMINT-558198.
STRINGi4932.YHR087W.

Proteomic databases

MaxQBiP38804.
PaxDbiP38804.
PeptideAtlasiP38804.

Protocols and materials databases

DNASUi856487.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR087W; YHR087W; YHR087W.
GeneIDi856487.
KEGGisce:YHR087W.

Organism-specific databases

CYGDiYHR087w.
SGDiS000001129. RTC3.

Phylogenomic databases

eggNOGiNOG81974.
HOGENOMiHOG000216667.
InParanoidiP38804.
OMAiTEGEIHE.
OrthoDBiEOG75J117.

Enzyme and pathway databases

BioCyciYEAST:G3O-31134-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP38804.
NextBioi982185.

Gene expression databases

GenevestigatoriP38804.

Family and domain databases

Gene3Di3.30.1250.10. 1 hit.
InterProiIPR019783. Ribosome_mat_SBDS_N.
[Graphical view]
PfamiPF01172. SBDS. 1 hit.
[Graphical view]
SUPFAMiSSF89895. SSF89895. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae."
    Addinall S.G., Downey M., Yu M., Zubko M.K., Dewar J., Leake A., Hallinan J., Shaw O., James K., Wilkinson D.J., Wipat A., Durocher D., Lydall D.
    Genetics 180:2251-2266(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. Cited for: STRUCTURE BY NMR.

Entry informationi

Entry nameiSDO1L_YEAST
AccessioniPrimary (citable) accession number: P38804
Secondary accession number(s): D3DL39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2430 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.