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Protein

Ribosome biogenesis protein SSF1

Gene

SSF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Required for biogenesis of the 60S ribosomal subunit.2 Publications

Miscellaneous

Present with 8150 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • rRNA binding Source: SGD

GO - Biological processi

  • conjugation with cellular fusion Source: SGD
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  • ribosomal large subunit assembly Source: SGD

Keywordsi

Biological processRibosome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-31117-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein SSF1
Gene namesi
Name:SSF1
Ordered Locus Names:YHR066W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR066W.
SGDiS000001108. SSF1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001202591 – 453Ribosome biogenesis protein SSF1Add BLAST453

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei301PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP38789.
PRIDEiP38789.

PTM databases

iPTMnetiP38789.

Interactioni

Subunit structurei

Part of a complex that includes BRX1, RPF1, RPF2 and SSF1 or SSF2.

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi36498. 295 interactors.
DIPiDIP-6501N.
IntActiP38789. 51 interactors.
MINTiMINT-612836.
STRINGi4932.YHR066W.

Structurei

3D structure databases

ProteinModelPortaliP38789.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 348BrixPROSITE-ProRule annotationAdd BLAST323

Phylogenomic databases

HOGENOMiHOG000210038.
InParanoidiP38789.
KOiK14859.
OMAiVTHLMLF.
OrthoDBiEOG092C3Q2K.

Family and domain databases

InterProiView protein in InterPro
IPR007109. Brix.
PfamiView protein in Pfam
PF04427. Brix. 1 hit.
SMARTiView protein in SMART
SM00879. Brix. 1 hit.
PROSITEiView protein in PROSITE
PS50833. BRIX. 1 hit.

Sequencei

Sequence statusi: Complete.

P38789-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRRQKKRT HAQLTPEQEQ GIPKSMVIRV GQTSLANHSL NQLVKDFRQI
60 70 80 90 100
MQPHTAIKLK ERKSNKLKDF VVMCGPLGVT HLFMFTQSEK TGNVSLKIAR
110 120 130 140 150
TPQGPTVTFQ VLDYSLGRDI KKFLKRPKSL NNDDVLNPPL LVLNGFSTSK
160 170 180 190 200
RSGEDDQDVN VEKVIVSMFQ NIFPPLNPAR TSLNSIKRVF MINKDRETGE
210 220 230 240 250
ISMRHYFIDI REVEISRNLK RLYKAKNNLS KTVPNLHRKE DISSLILDHD
260 270 280 290 300
LGAYTSESEI EDDAIVRVVD NQDVKAKHSQ SLKSQRTPVE KKDNKEREKE
310 320 330 340 350
TEEEDVEMEE PKPSENLQPT PRKKAIKLTE LGPRLTLKLV KIEEGICSGK
360 370 380 390 400
VLHHEFVQKS SEEIKALEKR HAAKMRLKEQ RKKEQEENIA KKKAVKDAKK
410 420 430 440 450
QRKLERRKAR AAEGGEGQGK DDAMSDDESS SSDSEHYGSV PEDLDSDLFS

EVE
Length:453
Mass (Da):51,764
Last modified:February 1, 1995 - v1
Checksum:i6F0344993BEF2217
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18113 Genomic DNA. Translation: AAA79980.1.
U00061 Genomic DNA. Translation: AAB68379.1.
BK006934 Genomic DNA. Translation: DAA06759.1.
PIRiS46700.
RefSeqiNP_011933.1. NM_001179196.1.

Genome annotation databases

EnsemblFungiiYHR066W; YHR066W; YHR066W.
GeneIDi856463.
KEGGisce:YHR066W.

Similar proteinsi

Entry informationi

Entry nameiSSF1_YEAST
AccessioniPrimary (citable) accession number: P38789
Secondary accession number(s): D3DL15
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 22, 2017
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names