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P38772

- BCD1_YEAST

UniProt

P38772 - BCD1_YEAST

Protein

Box C/D snoRNA protein 1

Gene

BCD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri5 – 3935HIT-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. nucleic acid binding Source: SGD

    GO - Biological processi

    1. ribosome biogenesis Source: UniProtKB-KW
    2. snoRNA metabolic process Source: SGD

    Keywords - Biological processi

    Ribosome biogenesis

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31099-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Box C/D snoRNA protein 1
    Gene namesi
    Name:BCD1
    Ordered Locus Names:YHR040W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHR040w.
    SGDiS000001082. BCD1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 366366Box C/D snoRNA protein 1PRO_0000173558Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei330 – 3301Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP38772.
    PaxDbiP38772.
    PeptideAtlasiP38772.

    Expressioni

    Gene expression databases

    GenevestigatoriP38772.

    Interactioni

    Protein-protein interaction databases

    BioGridi36472. 7 interactions.
    DIPiDIP-3862N.
    IntActiP38772. 7 interactions.
    MINTiMINT-512945.
    STRINGi4932.YHR040W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38772.
    SMRiP38772. Positions 2-48.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the BCD1 family.Curated
    Contains 1 HIT-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri5 – 3935HIT-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG279669.
    GeneTreeiENSGT00390000017201.
    HOGENOMiHOG000000870.
    OMAiDAVPMNI.
    OrthoDBiEOG7ZSJ63.

    Family and domain databases

    InterProiIPR007529. Znf_HIT.
    [Graphical view]
    PfamiPF04438. zf-HIT. 1 hit.
    [Graphical view]
    PROSITEiPS51083. ZF_HIT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P38772-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVLCGVCGI KEFKYKCPRC LVQTCSLECS KKHKTRDNCS GQTHDPKEYI    50
    SSEALKQADD DKHERNAYVQ RDYNYLTQLK RMVHVQKMDA RMKNKRVLGP 100
    VGGHNSNFKK RRYDIDEDDR DSTECQRIIR RGVNCLMLPK GMQRSSQNRS 150
    KWDKTMDLFV WSVEWILCPM QEKGEKKELF KHVSHRIKET DFLVQGMGKN 200
    VFQKCCEFYR LAGTSSCIEG EDGSETKEER TQILQKSGLK FYTKTFPYNT 250
    THIMDSKKLV ELAIHEKCIG ELLKNTTVIE FPTIFVAMTE ADLPEGYEVL 300
    HQEPRPLEHT STLNKFIDNA REEEDAEEDS QPTEEPVQKE TQDASDSDSD 350
    SDDDYNPGLS MDFLTA 366
    Length:366
    Mass (Da):42,334
    Last modified:February 1, 1995 - v1
    Checksum:iEE8BDAF489EC1F12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00062 Genomic DNA. Translation: AAB68905.1.
    BK006934 Genomic DNA. Translation: DAA06732.1.
    PIRiS46736.
    RefSeqiNP_011906.1. NM_001179170.1.

    Genome annotation databases

    EnsemblFungiiYHR040W; YHR040W; YHR040W.
    GeneIDi856436.
    KEGGisce:YHR040W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00062 Genomic DNA. Translation: AAB68905.1 .
    BK006934 Genomic DNA. Translation: DAA06732.1 .
    PIRi S46736.
    RefSeqi NP_011906.1. NM_001179170.1.

    3D structure databases

    ProteinModelPortali P38772.
    SMRi P38772. Positions 2-48.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36472. 7 interactions.
    DIPi DIP-3862N.
    IntActi P38772. 7 interactions.
    MINTi MINT-512945.
    STRINGi 4932.YHR040W.

    Proteomic databases

    MaxQBi P38772.
    PaxDbi P38772.
    PeptideAtlasi P38772.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHR040W ; YHR040W ; YHR040W .
    GeneIDi 856436.
    KEGGi sce:YHR040W.

    Organism-specific databases

    CYGDi YHR040w.
    SGDi S000001082. BCD1.

    Phylogenomic databases

    eggNOGi NOG279669.
    GeneTreei ENSGT00390000017201.
    HOGENOMi HOG000000870.
    OMAi DAVPMNI.
    OrthoDBi EOG7ZSJ63.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31099-MONOMER.

    Miscellaneous databases

    NextBioi 982036.

    Gene expression databases

    Genevestigatori P38772.

    Family and domain databases

    InterProi IPR007529. Znf_HIT.
    [Graphical view ]
    Pfami PF04438. zf-HIT. 1 hit.
    [Graphical view ]
    PROSITEi PS51083. ZF_HIT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: FUNCTION.
    4. Cited for: SUBCELLULAR LOCATION.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
      Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
      J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: ADR376.
    8. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-330, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiBCD1_YEAST
    AccessioniPrimary (citable) accession number: P38772
    Secondary accession number(s): D3DKY8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2800 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3