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Protein

Box C/D snoRNA protein 1

Gene

BCD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.1 Publication

Miscellaneous

Present with 2800 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri5 – 39HIT-typePROSITE-ProRule annotationAdd BLAST35

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • nucleic acid binding Source: SGD

GO - Biological processi

  • ribosome biogenesis Source: UniProtKB-KW
  • snoRNA metabolic process Source: SGD

Keywordsi

Biological processRibosome biogenesis
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-31099-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Box C/D snoRNA protein 1
Gene namesi
Name:BCD1
Ordered Locus Names:YHR040W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR040W
SGDiS000001082 BCD1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001735581 – 366Box C/D snoRNA protein 1Add BLAST366

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei330PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP38772
PaxDbiP38772
PRIDEiP38772

PTM databases

iPTMnetiP38772

Interactioni

Protein-protein interaction databases

BioGridi36472, 201 interactors
DIPiDIP-3862N
IntActiP38772, 14 interactors
STRINGi4932.YHR040W

Structurei

Secondary structure

1366
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 8Combined sources3
Turni18 – 20Combined sources3
Helixi27 – 37Combined sources11
Beta strandi41 – 43Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2N94NMR-A1-45[»]
ProteinModelPortaliP38772
SMRiP38772
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BCD1 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri5 – 39HIT-typePROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00390000017201
HOGENOMiHOG000000870
InParanoidiP38772
OMAiYACPKCE
OrthoDBiEOG092C16CL

Family and domain databases

InterProiView protein in InterPro
IPR007529 Znf_HIT
PfamiView protein in Pfam
PF04438 zf-HIT, 1 hit
PROSITEiView protein in PROSITE
PS51083 ZF_HIT, 1 hit

Sequencei

Sequence statusi: Complete.

P38772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVLCGVCGI KEFKYKCPRC LVQTCSLECS KKHKTRDNCS GQTHDPKEYI
60 70 80 90 100
SSEALKQADD DKHERNAYVQ RDYNYLTQLK RMVHVQKMDA RMKNKRVLGP
110 120 130 140 150
VGGHNSNFKK RRYDIDEDDR DSTECQRIIR RGVNCLMLPK GMQRSSQNRS
160 170 180 190 200
KWDKTMDLFV WSVEWILCPM QEKGEKKELF KHVSHRIKET DFLVQGMGKN
210 220 230 240 250
VFQKCCEFYR LAGTSSCIEG EDGSETKEER TQILQKSGLK FYTKTFPYNT
260 270 280 290 300
THIMDSKKLV ELAIHEKCIG ELLKNTTVIE FPTIFVAMTE ADLPEGYEVL
310 320 330 340 350
HQEPRPLEHT STLNKFIDNA REEEDAEEDS QPTEEPVQKE TQDASDSDSD
360
SDDDYNPGLS MDFLTA
Length:366
Mass (Da):42,334
Last modified:February 1, 1995 - v1
Checksum:iEE8BDAF489EC1F12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00062 Genomic DNA Translation: AAB68905.1
BK006934 Genomic DNA Translation: DAA06732.1
PIRiS46736
RefSeqiNP_011906.1, NM_001179170.1

Genome annotation databases

EnsemblFungiiYHR040W; YHR040W; YHR040W
GeneIDi856436
KEGGisce:YHR040W

Similar proteinsi

Entry informationi

Entry nameiBCD1_YEAST
AccessioniPrimary (citable) accession number: P38772
Secondary accession number(s): D3DKY8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health