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P38772 (BCD1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Box C/D snoRNA protein 1
Gene names
Name:BCD1
Ordered Locus Names:YHR040W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis. Ref.3

Subcellular location

Cytoplasm. Nucleus Ref.4 Ref.5.

Miscellaneous

Present with 2800 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the BCD1 family.

Contains 1 HIT-type zinc finger.

Ontologies

Keywords
   Biological processRibosome biogenesis
   Cellular componentCytoplasm
Nucleus
   DomainZinc-finger
   LigandMetal-binding
Zinc
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processribosome biogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

snoRNA metabolic process

Inferred from mutant phenotype Ref.3. Source: SGD

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleic acid binding

Non-traceable author statement Ref.3. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366Box C/D snoRNA protein 1
PRO_0000173558

Regions

Zinc finger5 – 3935HIT-type

Amino acid modifications

Modified residue3301Phosphoserine Ref.8

Sequences

Sequence LengthMass (Da)Tools
P38772 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: EE8BDAF489EC1F12

FASTA36642,334
        10         20         30         40         50         60 
MAVLCGVCGI KEFKYKCPRC LVQTCSLECS KKHKTRDNCS GQTHDPKEYI SSEALKQADD 

        70         80         90        100        110        120 
DKHERNAYVQ RDYNYLTQLK RMVHVQKMDA RMKNKRVLGP VGGHNSNFKK RRYDIDEDDR 

       130        140        150        160        170        180 
DSTECQRIIR RGVNCLMLPK GMQRSSQNRS KWDKTMDLFV WSVEWILCPM QEKGEKKELF 

       190        200        210        220        230        240 
KHVSHRIKET DFLVQGMGKN VFQKCCEFYR LAGTSSCIEG EDGSETKEER TQILQKSGLK 

       250        260        270        280        290        300 
FYTKTFPYNT THIMDSKKLV ELAIHEKCIG ELLKNTTVIE FPTIFVAMTE ADLPEGYEVL 

       310        320        330        340        350        360 
HQEPRPLEHT STLNKFIDNA REEEDAEEDS QPTEEPVQKE TQDASDSDSD SDDDYNPGLS 


MDFLTA 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"A panoramic view of yeast noncoding RNA processing."
Peng W.-T., Robinson M.D., Mnaimneh S., Krogan N.J., Cagney G., Morris Q.D., Davierwala A.P., Grigull J., Yang X., Zhang W., Mitsakakis N., Ryan O.W., Datta N., Jojic V., Pal C., Canadien V., Richards D.P., Beattie B. expand/collapse author list , Wu L.F., Altschuler S.J., Roweis S., Frey B.J., Emili A., Greenblatt J.F., Hughes T.R.
Cell 113:919-933(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[4]"Assigning function to yeast proteins by integration of technologies."
Hazbun T.R., Malmstroem L., Anderson S., Graczyk B.J., Fox B., Riffle M., Sundin B.A., Aranda J.D., McDonald W.H., Chiu C.-H., Snydsman B.E., Bradley P., Muller E.G.D., Fields S., Baker D., Yates J.R. III, Davis T.N.
Mol. Cell 12:1353-1365(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-330, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00062 Genomic DNA. Translation: AAB68905.1.
BK006934 Genomic DNA. Translation: DAA06732.1.
PIRS46736.
RefSeqNP_011906.1. NM_001179170.1.

3D structure databases

ProteinModelPortalP38772.
SMRP38772. Positions 2-48.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36472. 7 interactions.
DIPDIP-3862N.
IntActP38772. 7 interactions.
MINTMINT-512945.
STRING4932.YHR040W.

Proteomic databases

MaxQBP38772.
PaxDbP38772.
PeptideAtlasP38772.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR040W; YHR040W; YHR040W.
GeneID856436.
KEGGsce:YHR040W.

Organism-specific databases

CYGDYHR040w.
SGDS000001082. BCD1.

Phylogenomic databases

eggNOGNOG279669.
GeneTreeENSGT00390000017201.
HOGENOMHOG000000870.
OMADAVPMNI.
OrthoDBEOG7ZSJ63.

Enzyme and pathway databases

BioCycYEAST:G3O-31099-MONOMER.

Gene expression databases

GenevestigatorP38772.

Family and domain databases

InterProIPR007529. Znf_HIT.
[Graphical view]
PfamPF04438. zf-HIT. 1 hit.
[Graphical view]
PROSITEPS51083. ZF_HIT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982036.

Entry information

Entry nameBCD1_YEAST
AccessionPrimary (citable) accession number: P38772
Secondary accession number(s): D3DKY8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families