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Protein

Uncharacterized isomerase YHI9

Gene

YHI9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei52By similarity1

GO - Molecular functioni

GO - Biological processi

  • biosynthetic process Source: InterPro
  • endoplasmic reticulum unfolded protein response Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciYEAST:G3O-31089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized isomerase YHI9 (EC:5.1.-.-)
Gene namesi
Name:YHI9
Ordered Locus Names:YHR029C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR029C.
SGDiS000001071. YHI9.

Pathology & Biotechi

Disruption phenotypei

Leads to defects in unfolded protein response.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001623871 – 294Uncharacterized isomerase YHI9Add BLAST294

Proteomic databases

MaxQBiP38765.
PRIDEiP38765.

Interactioni

Protein-protein interaction databases

BioGridi36460. 21 interactors.
IntActiP38765. 12 interactors.
MINTiMINT-2492181.

Structurei

Secondary structure

1294
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 12Combined sources10
Beta strandi19 – 27Combined sources9
Helixi33 – 35Combined sources3
Helixi38 – 48Combined sources11
Beta strandi53 – 57Combined sources5
Beta strandi65 – 71Combined sources7
Beta strandi76 – 78Combined sources3
Helixi81 – 94Combined sources14
Beta strandi101 – 107Combined sources7
Beta strandi110 – 117Combined sources8
Beta strandi120 – 124Combined sources5
Beta strandi129 – 132Combined sources4
Helixi135 – 145Combined sources11
Beta strandi154 – 166Combined sources13
Helixi170 – 175Combined sources6
Helixi180 – 190Combined sources11
Beta strandi194 – 200Combined sources7
Beta strandi209 – 216Combined sources8
Helixi217 – 219Combined sources3
Beta strandi221 – 226Combined sources6
Helixi228 – 242Combined sources15
Beta strandi248 – 254Combined sources7
Helixi256 – 258Combined sources3
Beta strandi262 – 270Combined sources9
Beta strandi276 – 282Combined sources7
Beta strandi284 – 294Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YM5X-ray2.05A1-294[»]
ProteinModelPortaliP38765.
SMRiP38765.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP38765.

Family & Domainsi

Sequence similaritiesi

Belongs to the PhzF family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000017595.
HOGENOMiHOG000251511.
InParanoidiP38765.
OMAiAFAPVIN.
OrthoDBiEOG092C38U7.

Family and domain databases

InterProiIPR003719. Phenazine_PhzF.
[Graphical view]
PfamiPF02567. PhzC-PhzF. 1 hit.
[Graphical view]
PIRSFiPIRSF016184. PhzC_PhzF. 1 hit.
TIGRFAMsiTIGR00654. PhzF_family. 1 hit.

Sequencei

Sequence statusi: Complete.

P38765-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLMVPFKQV DVFTEKPFMG NPVAVINFLE IDENEVSQEE LQAIANWTNL
60 70 80 90 100
SETTFLFKPS DKKYDYKLRI FTPRSELPFA GHPTIGSCKA FLEFTKNTTA
110 120 130 140 150
TSLVQECKIG AVPITINEGL ISFKAPMADY ESISSEMIAD YEKAIGLKFI
160 170 180 190 200
KPPALLHTGP EWIVALVEDA ETCFNANPNF AMLAHQTKQN DHVGIILAGP
210 220 230 240 250
KKEAAIKNSY EMRAFAPVIN VYEDPVCGSG SVALARYLQE VYKFEKTTDI
260 270 280 290
TISEGGRLKR NGLMLASIKK EADNSTSYYI AGHATTVIDG KIKV
Length:294
Mass (Da):32,563
Last modified:February 1, 1995 - v1
Checksum:iADD1315AF7DA60E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10399 Genomic DNA. Translation: AAB68880.1.
AY557826 Genomic DNA. Translation: AAS56152.1.
BK006934 Genomic DNA. Translation: DAA06720.1.
PIRiS46781.
RefSeqiNP_011894.1. NM_001179159.1.

Genome annotation databases

EnsemblFungiiYHR029C; YHR029C; YHR029C.
GeneIDi856424.
KEGGisce:YHR029C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10399 Genomic DNA. Translation: AAB68880.1.
AY557826 Genomic DNA. Translation: AAS56152.1.
BK006934 Genomic DNA. Translation: DAA06720.1.
PIRiS46781.
RefSeqiNP_011894.1. NM_001179159.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YM5X-ray2.05A1-294[»]
ProteinModelPortaliP38765.
SMRiP38765.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36460. 21 interactors.
IntActiP38765. 12 interactors.
MINTiMINT-2492181.

Proteomic databases

MaxQBiP38765.
PRIDEiP38765.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR029C; YHR029C; YHR029C.
GeneIDi856424.
KEGGisce:YHR029C.

Organism-specific databases

EuPathDBiFungiDB:YHR029C.
SGDiS000001071. YHI9.

Phylogenomic databases

GeneTreeiENSGT00390000017595.
HOGENOMiHOG000251511.
InParanoidiP38765.
OMAiAFAPVIN.
OrthoDBiEOG092C38U7.

Enzyme and pathway databases

BioCyciYEAST:G3O-31089-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP38765.
PROiP38765.

Family and domain databases

InterProiIPR003719. Phenazine_PhzF.
[Graphical view]
PfamiPF02567. PhzC-PhzF. 1 hit.
[Graphical view]
PIRSFiPIRSF016184. PhzC_PhzF. 1 hit.
TIGRFAMsiTIGR00654. PhzF_family. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYHI9_YEAST
AccessioniPrimary (citable) accession number: P38765
Secondary accession number(s): D3DKX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.