Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized isomerase YHI9

Gene

YHI9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei52 – 521By similarity

GO - Molecular functioni

GO - Biological processi

  • biosynthetic process Source: InterPro
  • endoplasmic reticulum unfolded protein response Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciYEAST:G3O-31089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized isomerase YHI9 (EC:5.1.-.-)
Gene namesi
Name:YHI9
Ordered Locus Names:YHR029C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR029C.
SGDiS000001071. YHI9.

Pathology & Biotechi

Disruption phenotypei

Leads to defects in unfolded protein response.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 294294Uncharacterized isomerase YHI9PRO_0000162387Add
BLAST

Proteomic databases

MaxQBiP38765.
PRIDEiP38765.

Interactioni

Protein-protein interaction databases

BioGridi36460. 21 interactions.
IntActiP38765. 12 interactions.
MINTiMINT-2492181.

Structurei

Secondary structure

1
294
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 1210Combined sources
Beta strandi19 – 279Combined sources
Helixi33 – 353Combined sources
Helixi38 – 4811Combined sources
Beta strandi53 – 575Combined sources
Beta strandi65 – 717Combined sources
Beta strandi76 – 783Combined sources
Helixi81 – 9414Combined sources
Beta strandi101 – 1077Combined sources
Beta strandi110 – 1178Combined sources
Beta strandi120 – 1245Combined sources
Beta strandi129 – 1324Combined sources
Helixi135 – 14511Combined sources
Beta strandi154 – 16613Combined sources
Helixi170 – 1756Combined sources
Helixi180 – 19011Combined sources
Beta strandi194 – 2007Combined sources
Beta strandi209 – 2168Combined sources
Helixi217 – 2193Combined sources
Beta strandi221 – 2266Combined sources
Helixi228 – 24215Combined sources
Beta strandi248 – 2547Combined sources
Helixi256 – 2583Combined sources
Beta strandi262 – 2709Combined sources
Beta strandi276 – 2827Combined sources
Beta strandi284 – 29411Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YM5X-ray2.05A1-294[»]
ProteinModelPortaliP38765.
SMRiP38765. Positions 2-294.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP38765.

Family & Domainsi

Sequence similaritiesi

Belongs to the PhzF family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000017595.
HOGENOMiHOG000251511.
InParanoidiP38765.
OMAiANACIAR.
OrthoDBiEOG7HQNKV.

Family and domain databases

InterProiIPR003719. Phenazine_PhzF.
[Graphical view]
PfamiPF02567. PhzC-PhzF. 1 hit.
[Graphical view]
PIRSFiPIRSF016184. PhzC_PhzF. 1 hit.
TIGRFAMsiTIGR00654. PhzF_family. 1 hit.

Sequencei

Sequence statusi: Complete.

P38765-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLMVPFKQV DVFTEKPFMG NPVAVINFLE IDENEVSQEE LQAIANWTNL
60 70 80 90 100
SETTFLFKPS DKKYDYKLRI FTPRSELPFA GHPTIGSCKA FLEFTKNTTA
110 120 130 140 150
TSLVQECKIG AVPITINEGL ISFKAPMADY ESISSEMIAD YEKAIGLKFI
160 170 180 190 200
KPPALLHTGP EWIVALVEDA ETCFNANPNF AMLAHQTKQN DHVGIILAGP
210 220 230 240 250
KKEAAIKNSY EMRAFAPVIN VYEDPVCGSG SVALARYLQE VYKFEKTTDI
260 270 280 290
TISEGGRLKR NGLMLASIKK EADNSTSYYI AGHATTVIDG KIKV
Length:294
Mass (Da):32,563
Last modified:February 1, 1995 - v1
Checksum:iADD1315AF7DA60E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10399 Genomic DNA. Translation: AAB68880.1.
AY557826 Genomic DNA. Translation: AAS56152.1.
BK006934 Genomic DNA. Translation: DAA06720.1.
PIRiS46781.
RefSeqiNP_011894.1. NM_001179159.1.

Genome annotation databases

EnsemblFungiiYHR029C; YHR029C; YHR029C.
GeneIDi856424.
KEGGisce:YHR029C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10399 Genomic DNA. Translation: AAB68880.1.
AY557826 Genomic DNA. Translation: AAS56152.1.
BK006934 Genomic DNA. Translation: DAA06720.1.
PIRiS46781.
RefSeqiNP_011894.1. NM_001179159.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YM5X-ray2.05A1-294[»]
ProteinModelPortaliP38765.
SMRiP38765. Positions 2-294.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36460. 21 interactions.
IntActiP38765. 12 interactions.
MINTiMINT-2492181.

Proteomic databases

MaxQBiP38765.
PRIDEiP38765.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR029C; YHR029C; YHR029C.
GeneIDi856424.
KEGGisce:YHR029C.

Organism-specific databases

EuPathDBiFungiDB:YHR029C.
SGDiS000001071. YHI9.

Phylogenomic databases

GeneTreeiENSGT00390000017595.
HOGENOMiHOG000251511.
InParanoidiP38765.
OMAiANACIAR.
OrthoDBiEOG7HQNKV.

Enzyme and pathway databases

BioCyciYEAST:G3O-31089-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP38765.
PROiP38765.

Family and domain databases

InterProiIPR003719. Phenazine_PhzF.
[Graphical view]
PfamiPF02567. PhzC-PhzF. 1 hit.
[Graphical view]
PIRSFiPIRSF016184. PhzC_PhzF. 1 hit.
TIGRFAMsiTIGR00654. PhzF_family. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: DISRUPTION PHENOTYPE.
  5. "Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily."
    Liger D., Quevillon-Cheruel S., Sorel I., Bremang M., Blondeau K., Aboulfath I., Janin J., van Tilbeurgh H., Leulliot N.
    Proteins 60:778-786(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS).

Entry informationi

Entry nameiYHI9_YEAST
AccessioniPrimary (citable) accession number: P38765
Secondary accession number(s): D3DKX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 6, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.