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Protein

RNA-binding protein MIP6

Gene

MIP6

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 98 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • RNA binding Source: SGD

GO - Biological processi

  • mRNA export from nucleus Source: SGD

Keywordsi

Molecular functionRNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31077-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein MIP6
Alternative name(s):
MEX67-interacting protein 6
Gene namesi
Name:MIP6
Ordered Locus Names:YHR015W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR015W
SGDiS000001057 MIP6

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000820321 – 659RNA-binding protein MIP6Add BLAST659

Proteomic databases

PaxDbiP38760
PRIDEiP38760

Interactioni

Subunit structurei

Interacts with MEX67.1 Publication

Protein-protein interaction databases

BioGridi36444, 30 interactors
DIPiDIP-6647N
IntActiP38760, 12 interactors
STRINGi4932.YHR015W

Structurei

Secondary structure

1659
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi314 – 318Combined sources5
Helixi326 – 333Combined sources8
Turni334 – 336Combined sources3
Beta strandi339 – 344Combined sources6
Beta strandi354 – 361Combined sources8
Helixi362 – 372Combined sources11
Beta strandi375 – 377Combined sources3
Beta strandi380 – 386Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5D77X-ray1.30A313-388[»]
5D78X-ray1.25A313-387[»]
ProteinModelPortaliP38760
SMRiP38760
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 189RRM 1PROSITE-ProRule annotationAdd BLAST79
Domaini199 – 267RRM 2PROSITE-ProRule annotationAdd BLAST69
Domaini313 – 389RRM 3PROSITE-ProRule annotationAdd BLAST77

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00790000123919
HOGENOMiHOG000000869
InParanoidiP38760
OMAiTEWIARE
OrthoDBiEOG092C3WHA

Family and domain databases

Gene3Di3.30.70.330, 4 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
SMARTiView protein in SMART
SM00360 RRM, 4 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

Sequencei

Sequence statusi: Complete.

P38760-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNSHGNVLN NISLNSKQNP RSISKSCPND KDARQKSFKT ISAQALVRVQ
60 70 80 90 100
GAGYKLGDVK LKDAEVKEKN SLKKYDCKNA TQEKKEQEQV FEKTVAKGSV
110 120 130 140 150
QKYITKTSKT NSLFIGNLKS TVTEEMLRKI FKRYQSFESA KVCRDFLTKK
160 170 180 190 200
SLGYGYLNFK DKNDAESARK EFNYTVFFGQ EVKIMPSMKN TLFRKNIGTN
210 220 230 240 250
VFFSNLPLEN PQLTTRSFYL IMIEYGNVLS CLLERRKNIG FVYFDNDISA
260 270 280 290 300
RNVIKKYNNQ EFFGNKIICG LHFDKEVRTR PEFTKRKKMI GSDIVIEDEL
310 320 330 340 350
LASNNLSDNA RSKTILVKNL PSDTTQEEVL DYFSTIGPIK SVFISEKQAN
360 370 380 390 400
TPHKAFVTYK NEEESKKAQK CLNKTIFKNH TIWVGPGKDK PVHNQIGTNK
410 420 430 440 450
KTKVYLKNLS FNCNKEFISQ LCLQEKIRFS EIKITNYNSL NWTFCGHVEC
460 470 480 490 500
FSRSDAERLF NILDRRLIGS SLVEASWSKN NDNILNEIDY DDGNNNENYK
510 520 530 540 550
KLINISSMMR FRTQELSAHQ KGLTSQFQQV VSPFSSYSNS YTNMNSLVAT
560 570 580 590 600
PMKPHPAFNL ITNTVDEKLH QPKRTKQENA EILESLKKII NRNLQRISIS
610 620 630 640 650
GLNKEENLRS ISEFIFDVFW EHDSERLSHF LLMTNTSLES QKILQKQVTR

AAESLGFTV
Length:659
Mass (Da):75,920
Last modified:February 1, 1995 - v1
Checksum:iDF8E3F4D12A63871
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10400 Genomic DNA Translation: AAB68942.1
BK006934 Genomic DNA Translation: DAA06704.1
PIRiS46788
RefSeqiNP_011879.1, NM_001179145.1

Genome annotation databases

EnsemblFungiiYHR015W; YHR015W; YHR015W
GeneIDi856408
KEGGisce:YHR015W

Similar proteinsi

Entry informationi

Entry nameiMIP6_YEAST
AccessioniPrimary (citable) accession number: P38760
Secondary accession number(s): D3DKW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health