Reviewed, UniProtKB/Swiss-Prot P38751 (SHU1_YEAST)

Names and origin

Protein names

Recommended name:
    Suppressor of HU sensitivity involved in recombination protein 1

Gene names

Name:	SHU1
Ordered Locus Names:	YHL006C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	150 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May be involved in DNA recombination.
Sequence caution	The sequence AAA35196.1 differs from that shown. Reason: Frameshift at position 106.

Ontologies

Keywords
Biological process	DNA recombination
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	error-free DNA repair Inferred from mutant phenotype. Source: SGD recombinational repair Inferred from genetic interaction. Source: SGD
Cellular component	nucleus Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	P38957	1	EBI-24305,EBI-22154
ERG11	P10614	1	EBI-24305,EBI-5127

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 150	150	Suppressor of HU sensitivity involved in recombination protein 1		PRO_0000097742
Experimental info
	Sequence conflict	138	1	P → A Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P38751-1 [UniParc]. Last modified July 30, 2004. Version 2. Checksum: 8B17700BDAA2367F	FASTA	150	17,121
	10 20 30 40 50 60 MQFEERLQQL VESDWSLDQS SPNVLVIVLG DTARKYVELG GLKEHVTTNT VAGHVASRER 70 80 90 100 110 120 VSVVFLGRVK YLYMYLTRMQ AQANGPQYSN VLVYGLWDLT ATQDGPQQLR LLSLVLRQCL 130 140 150 SLPSKVEFYP EPPSSSVPAR LLRFWDHIIR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Fisk D., Cherry J.M. Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION TO C-TERMINUS.
[3]	Dignard D. Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U11581 Genomic DNA. Translation: AAB69748.2. L09261 Genomic DNA. Translation: AAA35196.1. Frameshift.
PIR	S46822.
RefSeq	NP_011857.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1874N.
IntAct	P38751. 9 interactions.
STRING	P38751.
Genome annotation databases
Ensembl	YHL006C; YHL006C; YHL006C; Saccharomyces cerevisiae. [Genome view]
GeneID	856383.
KEGG	sce:YHL006C.
NMPDR	fig|4932.3.peg.3000.
Organism-specific databases
CYGD	YHL006c.
SGD	S000000998. SHU1.
Phylogenomic databases
OrthoDB	EOG98GXMN
Gene expression databases
ArrayExpress	P38751.
Genevestigator	P38751.
GermOnline	YHL006C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	981884.

Entry information

Entry name

SHU1_YEAST

Accession

Primary (citable) accession number: P38751
Secondary accession number(s): Q07190

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	July 30, 2004
Last modified:	November 24, 2009
This is version 54 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)