P38747 (OTU2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
OTU domain-containing protein 2

Gene names

Name:	OTU2
Ordered Locus Names:	YHL013C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	Present with 172 molecules/cell in log phase SD medium.
Sequence similarities	Contains 1 OTU domain.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from direct assay PubMed 14562095. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	OTU domain-containing protein 2		PRO_0000202883
Regions
	Domain	167 – 307	141	OTU

Sequences

	Sequence		Length	Mass (Da)
	P38747 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 5580BF0459B78395	FASTA	307	36,113
	10 20 30 40 50 60 MTGMESGENL ENMEDILARH RKENKDLQNK ITGMKKQATK SKRKEVNSKC LDLQDKLKTK 70 80 90 100 110 120 QENEIRDWKI ANNEVFDAEQ EDEVTPEKLL EQLSISRDEK EQQNVPVQQQ QQGQTKKRRN 130 140 150 160 170 180 RQKERLAKRD AAIAKMKEEA ALEASKQPDL KKMEQESIDQ LCELKKLKQF DIQPDGHCLF 190 200 210 220 230 240 ASILDQLKLR HDPKKLDQDM DVMKLRWLSC NYVQEHRDDF IPYLFDEETM KMKDIDEYTK 250 260 270 280 290 300 EMEHTAQWGG EIEILALSHV FDCPISILMS GRPIQVYNEC GKNPELKLVY YKHSYALGEH YNSLHDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U11582 Genomic DNA. Translation: AAB65066.1. AY692608 Genomic DNA. Translation: AAT92627.1. BK006934 Genomic DNA. Translation: DAA06673.1.
PIR	S46827.
RefSeq	NP_011850.1. NM_001179093.1.
3D structure databases
ProteinModelPortal	P38747.
SMR	P38747. Positions 164-306.
ModBase	Search...
Protein-protein interaction databases
STRING	4932.YHL013C.
Protein family/group databases
MEROPS	C85.008.
Proteomic databases
PaxDb	P38747.
PeptideAtlas	P38747.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHL013C; YHL013C; YHL013C.
GeneID	856373.
KEGG	sce:YHL013C.
Organism-specific databases
CYGD	YHL013c.
SGD	S000001005. OTU2.
Phylogenomic databases
eggNOG	COG5539.
GeneTree	ENSGT00390000012840.
HOGENOM	HOG000192906.
OMA	HCLYRAV.
OrthoDB	EOG4VT96V.
Gene expression databases
Genevestigator	P38747.
GermOnline	YHL013C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR003323. OTU. [Graphical view]
Pfam	PF02338. OTU. 1 hit. [Graphical view]
PROSITE	PS50802. OTU. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	981855.

Entry information

Entry name

OTU2_YEAST

Accession

Primary (citable) accession number: P38747
Secondary accession number(s): D3DKQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program