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P38745

- YHB7_YEAST

UniProt

P38745 - YHB7_YEAST

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Protein
Uncharacterized membrane protein YHL071W
Gene
YHL017W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31037-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein YHL071W
Gene namesi
Ordered Locus Names:YHL017W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHL017w.
SGDiS000001009. YHL017W.

Subcellular locationi

Golgi apparatustrans-Golgi network membrane; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini21 – 193173Lumenal Reviewed prediction
Add
BLAST
Transmembranei194 – 21421Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini215 – 22612Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei227 – 24721Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini248 – 26215Lumenal Reviewed prediction
Add
BLAST
Transmembranei263 – 28321Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini284 – 30118Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei302 – 32221Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini323 – 3308Lumenal Reviewed prediction
Transmembranei331 – 35121Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini352 – 37524Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei376 – 39621Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini397 – 41418Lumenal Reviewed prediction
Add
BLAST
Transmembranei415 – 43521Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini436 – 53297Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. Golgi apparatus Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed prediction
Add
BLAST
Chaini21 – 532512Uncharacterized membrane protein YHL071W
PRO_0000014326Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi152 – 1521N-linked (GlcNAc...) Reviewed prediction
Glycosylationi253 – 2531N-linked (GlcNAc...) Reviewed prediction
Modified residuei497 – 4971Phosphoserine1 Publication

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiP38745.
PaxDbiP38745.
PeptideAtlasiP38745.

Expressioni

Gene expression databases

GenevestigatoriP38745.

Interactioni

Protein-protein interaction databases

BioGridi36406. 9 interactions.
DIPiDIP-4577N.
IntActiP38745. 4 interactions.
MINTiMINT-541074.
STRINGi4932.YHL017W.

Structurei

3D structure databases

ProteinModelPortaliP38745.

Family & Domainsi

Sequence similaritiesi

Belongs to the LU7TM family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG302490.
GeneTreeiENSGT00390000015417.
HOGENOMiHOG000176489.
OMAiCEDSSEG.
OrthoDBiEOG70ZZWZ.

Family and domain databases

InterProiIPR009637. TM_rcpt_euk.
[Graphical view]
PANTHERiPTHR21229. PTHR21229. 1 hit.
PfamiPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38745-1 [UniParc]FASTAAdd to Basket

« Hide

MDRTWLLLTW LLLLCGVVQG NQESINQKYH DVCSGMYSKE DFNGKVDPYI    50
SFTLEELSLA DEDDDGEGVS VAVFDFQDYE HIGVRLPNGE IQYICDDYAL 100
DLGLCEDSSE GQFIIQETAI DPFTSKEHKL TSQILTFTQQ ELGTNDKVYS 150
INKTGYYCVT TSSFISSSSK FKATVNFRNA YGQLDASEAY KMPIYAFLAV 200
AYAVCTLVYS WLCWKHRHEL LPLQRYILVF CIFLTADTIF VWMYYIIENQ 250
KGNSSVALHV YMVFISIFSA GKMTFTLLLA LLISLGYGIV YPKLDRTLLR 300
RCQIFAIFTF AVCVAFLVQK YSQNSESLSN LILITAIPLV LCLFAFYYLT 350
LSSMNKTMTY LREQNQVVKL NMYRKLIILC YISLFILFLG LLVSTFAYVG 400
MDTVDMIEQY WKTEFLITDT WPSFVYFLVF VIFAFFWRPT STSYLLACSH 450
QLPTDMENVS EFDLDDINSL SDEALPNREP RNDYQEHDHN MDIDLASDFE 500
EVPSVNANTN ANNDVLFDVD YDRDAKNDRS TT 532
Length:532
Mass (Da):61,206
Last modified:February 1, 1995 - v1
Checksum:iEF2CB7CB74006503
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U11582 Genomic DNA. Translation: AAB65070.1.
BK006934 Genomic DNA. Translation: DAA06668.1.
PIRiS46831.
RefSeqiNP_011846.1. NM_001179097.1.

Genome annotation databases

EnsemblFungiiYHL017W; YHL017W; YHL017W.
GeneIDi856369.
KEGGisce:YHL017W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U11582 Genomic DNA. Translation: AAB65070.1 .
BK006934 Genomic DNA. Translation: DAA06668.1 .
PIRi S46831.
RefSeqi NP_011846.1. NM_001179097.1.

3D structure databases

ProteinModelPortali P38745.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36406. 9 interactions.
DIPi DIP-4577N.
IntActi P38745. 4 interactions.
MINTi MINT-541074.
STRINGi 4932.YHL017W.

Proteomic databases

MaxQBi P38745.
PaxDbi P38745.
PeptideAtlasi P38745.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YHL017W ; YHL017W ; YHL017W .
GeneIDi 856369.
KEGGi sce:YHL017W.

Organism-specific databases

CYGDi YHL017w.
SGDi S000001009. YHL017W.

Phylogenomic databases

eggNOGi NOG302490.
GeneTreei ENSGT00390000015417.
HOGENOMi HOG000176489.
OMAi CEDSSEG.
OrthoDBi EOG70ZZWZ.

Enzyme and pathway databases

BioCyci YEAST:G3O-31037-MONOMER.

Miscellaneous databases

NextBioi 981843.
PROi P38745.

Gene expression databases

Genevestigatori P38745.

Family and domain databases

InterProi IPR009637. TM_rcpt_euk.
[Graphical view ]
PANTHERi PTHR21229. PTHR21229. 1 hit.
Pfami PF06814. Lung_7-TM_R. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  6. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-497, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYHB7_YEAST
AccessioniPrimary (citable) accession number: P38745
Secondary accession number(s): D3DKR6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 14600 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

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