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P38745 (YHB7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized membrane protein YHL071W
Gene names
Ordered Locus Names:YHL017W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Golgi apparatustrans-Golgi network membrane; Multi-pass membrane protein Ref.3.

Miscellaneous

Present with 14600 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the LU7TM family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 532512Uncharacterized membrane protein YHL071W
PRO_0000014326

Regions

Topological domain21 – 193173Lumenal Potential
Transmembrane194 – 21421Helical; Name=1; Potential
Topological domain215 – 22612Cytoplasmic Potential
Transmembrane227 – 24721Helical; Name=2; Potential
Topological domain248 – 26215Lumenal Potential
Transmembrane263 – 28321Helical; Name=3; Potential
Topological domain284 – 30118Cytoplasmic Potential
Transmembrane302 – 32221Helical; Name=4; Potential
Topological domain323 – 3308Lumenal Potential
Transmembrane331 – 35121Helical; Name=5; Potential
Topological domain352 – 37524Cytoplasmic Potential
Transmembrane376 – 39621Helical; Name=6; Potential
Topological domain397 – 41418Lumenal Potential
Transmembrane415 – 43521Helical; Name=7; Potential
Topological domain436 – 53297Cytoplasmic Potential

Amino acid modifications

Modified residue4971Phosphoserine Ref.6
Glycosylation1521N-linked (GlcNAc...) Potential
Glycosylation2531N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P38745 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: EF2CB7CB74006503

FASTA53261,206
        10         20         30         40         50         60 
MDRTWLLLTW LLLLCGVVQG NQESINQKYH DVCSGMYSKE DFNGKVDPYI SFTLEELSLA 

        70         80         90        100        110        120 
DEDDDGEGVS VAVFDFQDYE HIGVRLPNGE IQYICDDYAL DLGLCEDSSE GQFIIQETAI 

       130        140        150        160        170        180 
DPFTSKEHKL TSQILTFTQQ ELGTNDKVYS INKTGYYCVT TSSFISSSSK FKATVNFRNA 

       190        200        210        220        230        240 
YGQLDASEAY KMPIYAFLAV AYAVCTLVYS WLCWKHRHEL LPLQRYILVF CIFLTADTIF 

       250        260        270        280        290        300 
VWMYYIIENQ KGNSSVALHV YMVFISIFSA GKMTFTLLLA LLISLGYGIV YPKLDRTLLR 

       310        320        330        340        350        360 
RCQIFAIFTF AVCVAFLVQK YSQNSESLSN LILITAIPLV LCLFAFYYLT LSSMNKTMTY 

       370        380        390        400        410        420 
LREQNQVVKL NMYRKLIILC YISLFILFLG LLVSTFAYVG MDTVDMIEQY WKTEFLITDT 

       430        440        450        460        470        480 
WPSFVYFLVF VIFAFFWRPT STSYLLACSH QLPTDMENVS EFDLDDINSL SDEALPNREP 

       490        500        510        520        530 
RNDYQEHDHN MDIDLASDFE EVPSVNANTN ANNDVLFDVD YDRDAKNDRS TT 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
[6]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-497, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U11582 Genomic DNA. Translation: AAB65070.1.
BK006934 Genomic DNA. Translation: DAA06668.1.
PIRS46831.
RefSeqNP_011846.1. NM_001179097.1.

3D structure databases

ProteinModelPortalP38745.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36406. 9 interactions.
DIPDIP-4577N.
IntActP38745. 4 interactions.
MINTMINT-541074.
STRING4932.YHL017W.

Proteomic databases

MaxQBP38745.
PaxDbP38745.
PeptideAtlasP38745.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHL017W; YHL017W; YHL017W.
GeneID856369.
KEGGsce:YHL017W.

Organism-specific databases

CYGDYHL017w.
SGDS000001009. YHL017W.

Phylogenomic databases

eggNOGNOG302490.
GeneTreeENSGT00390000015417.
HOGENOMHOG000176489.
OMACEDSSEG.
OrthoDBEOG70ZZWZ.

Enzyme and pathway databases

BioCycYEAST:G3O-31037-MONOMER.

Gene expression databases

GenevestigatorP38745.

Family and domain databases

InterProIPR009637. TM_rcpt_euk.
[Graphical view]
PANTHERPTHR21229. PTHR21229. 1 hit.
PfamPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio981843.
PROP38745.

Entry information

Entry nameYHB7_YEAST
AccessionPrimary (citable) accession number: P38745
Secondary accession number(s): D3DKR6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families