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Protein

Uncharacterized membrane protein YHL071W

Gene

YHL017W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31037-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein YHL071W
Gene namesi
Ordered Locus Names:YHL017W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHL017W.
SGDiS000001009. YHL017W.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini21 – 193LumenalSequence analysisAdd BLAST173
Transmembranei194 – 214Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini215 – 226CytoplasmicSequence analysisAdd BLAST12
Transmembranei227 – 247Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini248 – 262LumenalSequence analysisAdd BLAST15
Transmembranei263 – 283Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini284 – 301CytoplasmicSequence analysisAdd BLAST18
Transmembranei302 – 322Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini323 – 330LumenalSequence analysis8
Transmembranei331 – 351Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini352 – 375CytoplasmicSequence analysisAdd BLAST24
Transmembranei376 – 396Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini397 – 414LumenalSequence analysisAdd BLAST18
Transmembranei415 – 435Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini436 – 532CytoplasmicSequence analysisAdd BLAST97

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000001432621 – 532Uncharacterized membrane protein YHL071WAdd BLAST512

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi152N-linked (GlcNAc...)Sequence analysis1
Glycosylationi253N-linked (GlcNAc...)Sequence analysis1
Modified residuei497PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiP38745.
PRIDEiP38745.

PTM databases

iPTMnetiP38745.

Interactioni

Protein-protein interaction databases

BioGridi36406. 8 interactors.
DIPiDIP-4577N.
IntActiP38745. 4 interactors.
MINTiMINT-541074.

Structurei

3D structure databases

ProteinModelPortaliP38745.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LU7TM family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000015417.
HOGENOMiHOG000176489.
InParanoidiP38745.
OMAiVYMVFIS.
OrthoDBiEOG092C26YZ.

Family and domain databases

InterProiIPR009637. GPR107-like.
[Graphical view]
PANTHERiPTHR21229. PTHR21229. 1 hit.
PfamiPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38745-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRTWLLLTW LLLLCGVVQG NQESINQKYH DVCSGMYSKE DFNGKVDPYI
60 70 80 90 100
SFTLEELSLA DEDDDGEGVS VAVFDFQDYE HIGVRLPNGE IQYICDDYAL
110 120 130 140 150
DLGLCEDSSE GQFIIQETAI DPFTSKEHKL TSQILTFTQQ ELGTNDKVYS
160 170 180 190 200
INKTGYYCVT TSSFISSSSK FKATVNFRNA YGQLDASEAY KMPIYAFLAV
210 220 230 240 250
AYAVCTLVYS WLCWKHRHEL LPLQRYILVF CIFLTADTIF VWMYYIIENQ
260 270 280 290 300
KGNSSVALHV YMVFISIFSA GKMTFTLLLA LLISLGYGIV YPKLDRTLLR
310 320 330 340 350
RCQIFAIFTF AVCVAFLVQK YSQNSESLSN LILITAIPLV LCLFAFYYLT
360 370 380 390 400
LSSMNKTMTY LREQNQVVKL NMYRKLIILC YISLFILFLG LLVSTFAYVG
410 420 430 440 450
MDTVDMIEQY WKTEFLITDT WPSFVYFLVF VIFAFFWRPT STSYLLACSH
460 470 480 490 500
QLPTDMENVS EFDLDDINSL SDEALPNREP RNDYQEHDHN MDIDLASDFE
510 520 530
EVPSVNANTN ANNDVLFDVD YDRDAKNDRS TT
Length:532
Mass (Da):61,206
Last modified:February 1, 1995 - v1
Checksum:iEF2CB7CB74006503
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11582 Genomic DNA. Translation: AAB65070.1.
BK006934 Genomic DNA. Translation: DAA06668.1.
PIRiS46831.
RefSeqiNP_011846.1. NM_001179097.1.

Genome annotation databases

EnsemblFungiiYHL017W; YHL017W; YHL017W.
GeneIDi856369.
KEGGisce:YHL017W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11582 Genomic DNA. Translation: AAB65070.1.
BK006934 Genomic DNA. Translation: DAA06668.1.
PIRiS46831.
RefSeqiNP_011846.1. NM_001179097.1.

3D structure databases

ProteinModelPortaliP38745.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36406. 8 interactors.
DIPiDIP-4577N.
IntActiP38745. 4 interactors.
MINTiMINT-541074.

PTM databases

iPTMnetiP38745.

Proteomic databases

MaxQBiP38745.
PRIDEiP38745.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHL017W; YHL017W; YHL017W.
GeneIDi856369.
KEGGisce:YHL017W.

Organism-specific databases

EuPathDBiFungiDB:YHL017W.
SGDiS000001009. YHL017W.

Phylogenomic databases

GeneTreeiENSGT00390000015417.
HOGENOMiHOG000176489.
InParanoidiP38745.
OMAiVYMVFIS.
OrthoDBiEOG092C26YZ.

Enzyme and pathway databases

BioCyciYEAST:G3O-31037-MONOMER.

Miscellaneous databases

PROiP38745.

Family and domain databases

InterProiIPR009637. GPR107-like.
[Graphical view]
PANTHERiPTHR21229. PTHR21229. 1 hit.
PfamiPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHB7_YEAST
AccessioniPrimary (citable) accession number: P38745
Secondary accession number(s): D3DKR6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 14600 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.