Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P38744

- PHS_YEAST

UniProt

P38744 - PHS_YEAST

Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

YHL018W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.

    GO - Molecular functioni

    1. 4-alpha-hydroxytetrahydrobiopterin dehydratase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tetrahydrobiopterin biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31038-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative pterin-4-alpha-carbinolamine dehydratase (EC:4.2.1.96)
    Short name:
    PHS
    Alternative name(s):
    4-alpha-hydroxy-tetrahydropterin dehydratase
    Pterin carbinolamine dehydratase
    Short name:
    PCD
    Gene namesi
    Ordered Locus Names:YHL018W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHL018w.
    SGDiS000001010. YHL018W.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 120120Putative pterin-4-alpha-carbinolamine dehydratasePRO_0000063064Add
    BLAST

    Proteomic databases

    MaxQBiP38744.
    PaxDbiP38744.

    Expressioni

    Gene expression databases

    GenevestigatoriP38744.

    Interactioni

    Protein-protein interaction databases

    BioGridi36405. 15 interactions.
    DIPiDIP-1872N.
    IntActiP38744. 13 interactions.
    MINTiMINT-404879.
    STRINGi4932.YHL018W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38744.
    SMRiP38744. Positions 8-112.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2154.
    HOGENOMiHOG000007680.
    OMAiRAYSECT.
    OrthoDBiEOG79GTM1.

    Family and domain databases

    Gene3Di3.30.1360.20. 1 hit.
    InterProiIPR001533. Trans/pterin_deHydtase.
    [Graphical view]
    PANTHERiPTHR12599. PTHR12599. 1 hit.
    PfamiPF01329. Pterin_4a. 1 hit.
    [Graphical view]
    SUPFAMiSSF55248. SSF55248. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P38744-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHNKIVRIAS SALTGGKLLE KLKPLTRWEV QWDPNKTKCL GITREVTFKD    50
    YETTWAFLTR VSMRSHLWGH HPLIHTSYTW VKLELHTHDI DPKDGAHSQL 100
    SDIDVRMAKR IDSYIDEMTT 120
    Length:120
    Mass (Da):14,026
    Last modified:February 1, 1995 - v1
    Checksum:i4265E895BD5CDB02
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11582 Genomic DNA. Translation: AAB65071.1.
    AY558391 Genomic DNA. Translation: AAS56717.1.
    BK006934 Genomic DNA. Translation: DAA06667.1.
    PIRiS46832.
    RefSeqiNP_011845.1. NM_001179098.1.

    Genome annotation databases

    EnsemblFungiiYHL018W; YHL018W; YHL018W.
    GeneIDi856368.
    KEGGisce:YHL018W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11582 Genomic DNA. Translation: AAB65071.1 .
    AY558391 Genomic DNA. Translation: AAS56717.1 .
    BK006934 Genomic DNA. Translation: DAA06667.1 .
    PIRi S46832.
    RefSeqi NP_011845.1. NM_001179098.1.

    3D structure databases

    ProteinModelPortali P38744.
    SMRi P38744. Positions 8-112.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36405. 15 interactions.
    DIPi DIP-1872N.
    IntActi P38744. 13 interactions.
    MINTi MINT-404879.
    STRINGi 4932.YHL018W.

    Proteomic databases

    MaxQBi P38744.
    PaxDbi P38744.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHL018W ; YHL018W ; YHL018W .
    GeneIDi 856368.
    KEGGi sce:YHL018W.

    Organism-specific databases

    CYGDi YHL018w.
    SGDi S000001010. YHL018W.

    Phylogenomic databases

    eggNOGi COG2154.
    HOGENOMi HOG000007680.
    OMAi RAYSECT.
    OrthoDBi EOG79GTM1.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31038-MONOMER.

    Miscellaneous databases

    NextBioi 981840.
    PROi P38744.

    Gene expression databases

    Genevestigatori P38744.

    Family and domain databases

    Gene3Di 3.30.1360.20. 1 hit.
    InterProi IPR001533. Trans/pterin_deHydtase.
    [Graphical view ]
    PANTHERi PTHR12599. PTHR12599. 1 hit.
    Pfami PF01329. Pterin_4a. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55248. SSF55248. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPHS_YEAST
    AccessioniPrimary (citable) accession number: P38744
    Secondary accession number(s): D3DKR5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 752 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3