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Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

YHL018W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 752 molecules/cell in log phase SD medium.1 Publication

Catalytic activityi

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciYEAST:G3O-31038-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase (EC:4.2.1.96)
Short name:
PHS
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name:
PCD
Gene namesi
Ordered Locus Names:YHL018W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHL018W.
SGDiS000001010. YHL018W.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000630641 – 120Putative pterin-4-alpha-carbinolamine dehydrataseAdd BLAST120

Proteomic databases

MaxQBiP38744.
PRIDEiP38744.

Interactioni

Protein-protein interaction databases

BioGridi36405. 78 interactors.
DIPiDIP-1872N.
IntActiP38744. 12 interactors.
MINTiMINT-404879.
STRINGi4932.YHL018W.

Structurei

3D structure databases

ProteinModelPortaliP38744.
SMRiP38744.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000007680.
InParanoidiP38744.
KOiK01724.
OMAiETTWAFL.
OrthoDBiEOG092C5V3T.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
InterProiView protein in InterPro
IPR036428. PCD_sf.
IPR001533. Pterin_deHydtase.
PfamiView protein in Pfam
PF01329. Pterin_4a. 1 hit.
SUPFAMiSSF55248. SSF55248. 1 hit.

Sequencei

Sequence statusi: Complete.

P38744-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHNKIVRIAS SALTGGKLLE KLKPLTRWEV QWDPNKTKCL GITREVTFKD
60 70 80 90 100
YETTWAFLTR VSMRSHLWGH HPLIHTSYTW VKLELHTHDI DPKDGAHSQL
110 120
SDIDVRMAKR IDSYIDEMTT
Length:120
Mass (Da):14,026
Last modified:February 1, 1995 - v1
Checksum:i4265E895BD5CDB02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11582 Genomic DNA. Translation: AAB65071.1.
AY558391 Genomic DNA. Translation: AAS56717.1.
BK006934 Genomic DNA. Translation: DAA06667.1.
PIRiS46832.
RefSeqiNP_011845.1. NM_001179098.1.

Genome annotation databases

EnsemblFungiiYHL018W; YHL018W; YHL018W.
GeneIDi856368.
KEGGisce:YHL018W.

Similar proteinsi

Entry informationi

Entry nameiPHS_YEAST
AccessioniPrimary (citable) accession number: P38744
Secondary accession number(s): D3DKR5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 25, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names