P38740 (YHC6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YHL026C

Gene names

Ordered Locus Names:

YHL026C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Miscellaneous	Present with 830 molecules/cell in log phase SD medium. Ref.6

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 315	315	Uncharacterized protein YHL026C		PRO_0000014325
Regions
	Transmembrane	18 – 38	21	Helical; Potential
	Transmembrane	202 – 222	21	Helical; Potential
	Transmembrane	244 – 264	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P38740 [UniParc]. Last modified May 16, 2006. Version 2. Checksum: 645BD3279530388F	FASTA	315	35,717
	10 20 30 40 50 60 MKSSEPAPAT PTGFRNSIWF IIFYLFVIQA LGSAIISGGI EFAIAYAMYH SRVDLITLWA 70 80 90 100 110 120 FPHTISGDCA LSLFIQVGLT WASEEILVGF DDYKRPVFRL NKWITKPSPL KTESNEEIPP 130 140 150 160 170 180 PKKRFIVDYF ESKDNVVAKQ NTLYHKHNWL FGYLEVNRGI IPKGKEATLK GFLTSQFIHD 190 200 210 220 230 240 STQSKFMNFI EWFVQKFIRS MILAIAMFIV IWPVTMGILA GIGHKVGSHD YYFNDYPLPQ 250 260 270 280 290 300 VMKLIYAVVI AFVCTPVAII VIVLRNQFHE ELYYEGLANG TLQQDQEVCS TGNRSSGSTD 310 QDISTTKQQS QEAVA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Hong E.L. Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION TO N-TERMINUS.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-315. Strain: ATCC 204508 / S288c.
[5]	"Finding functional features in Saccharomyces genomes by phylogenetic footprinting." Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J., Waterston R., Cohen B.A., Johnston M. Science 301:71-76(2003) [PubMed: 12775844] [Abstract] Cited for: IDENTIFICATION OF FRAMESHIFT.
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U11583 Genomic DNA. Translation: AAB65062.2. AY558104 Genomic DNA. Translation: AAS56430.1. BK006934 Genomic DNA. Translation: DAA06659.1.
PIR	S48942.
RefSeq	NP_011837.2. NM_001179106.1.
3D structure databases
ProteinModelPortal	P38740.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2744N.
IntAct	P38740. 2 interactions.
MINT	MINT-501361.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHL026C; YHL026C; YHL026C.
GeneID	856359.
KEGG	sce:YHL026C.
NMPDR	fig|4932.3.peg.2975.
Organism-specific databases
CYGD	YHL026c.
SGD	S000001018. YHL026C.
Phylogenomic databases
eggNOG	fuNOG13069.
GeneTree	EFGT00050000008566.
OMA	WPVTMGI.
OrthoDB	EOG4MSH7N.
Gene expression databases
ArrayExpress	P38740.
Genevestigator	P38740.
GermOnline	YHL026C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR018852. DUF2456. [Graphical view]
Pfam	PF10445. DUF2456. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	981814.

Entry information

Entry name

YHC6_YEAST

Accession

Primary (citable) accession number: P38740
Secondary accession number(s): D3DKU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	May 16, 2006
Last modified:	December 14, 2011
This is version 76 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program