Reviewed,
UniProtKB/Swiss-Prot P38739 (WSC4_YEAST)
Last modified
November 24, 2009.
Version 65.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Cell wall integrity and stress response component 4 | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 605 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subcellular location | Membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Contains 1 WSC domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell wall biogenesis/degradation |
| Cellular component | Membrane |
| Domain | Signal Transmembrane |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW protein targeting to ERInferred from mutant phenotype. Source: SGD response to heatInferred from genetic interaction. Source: SGD |
| Cellular component | endoplasmic reticulum membrane Inferred from direct assay. Source: SGD integral to membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct transmembrane receptor activityInferred from genetic interaction. Source: SGD |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| LSB3 | P43603 | 1 | EBI-20558,EBI-22980 | |
| YSC84 | P32793 | 1 | EBI-20558,EBI-24460 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 26 | 26 | Potential | ||||||
| Chain | 27 – 605 | 579 | Cell wall integrity and stress response component 4 | PRO_0000041486 | |||||
Regions | |||||||||
| Transmembrane | 415 – 435 | 21 | Potential | ||||||
| Domain | 27 – 110 | 84 | WSC | ||||||
| Compositional bias | 116 – 317 | 202 | Ser/Thr-rich | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 340 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 386 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 389 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 398 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 479 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 553 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 583 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| [1] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P.  Vaudin M.Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| U11583 Genomic DNA. Translation: AAB65040.1. | |
| PIR | S48940. |
| RefSeq | NP_011835.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P38739. 3 interactions. |
| STRING | P38739. |
Genome annotation databases | |
| Ensembl | YHL028W; YHL028W; YHL028W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 856357. |
| KEGG | sce:YHL028W. |
| NMPDR | fig|4932.3.peg.2973. |
Organism-specific databases | |
| CYGD | YHL028w. |
| SGD | S000001020. WSC4. |
Phylogenomic databases | |
| HOGENOM | P38739. |
| OMA | DDVDYSR |
| OrthoDB | EOG9ZPGBH |
Gene expression databases | |
| ArrayExpress | P38739. |
| Genevestigator | P38739. |
| GermOnline | YHL028W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR002889. WSC_carb_bd. [Graphical view] |
| Pfam | PF01822. WSC. 1 hit. [Graphical view] |
| PROSITE | PS51212. WSC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 981808. |
Entry information
| Entry name | WSC4_YEAST | ||||||||
| Accession | Primary (citable) accession number: P38739 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome VIII Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names |
