Reviewed, UniProtKB/Swiss-Prot P38728 (ECM34_YEAST)

Names and origin

Protein names

Recommended name:
    Protein ECM34
Alternative name(s):
    Extracellular mutant protein 34

Gene names

Name:	ECM34
Ordered Locus Names:	YHL043W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May be involved in cell wall organization and biogenesis.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the DUP/COS family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Membrane
Domain	Transmembrane
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fungal-type cell wall organization Ref.2 Inferred from mutant phenotype. Source: SGD
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 170	170	Protein ECM34		PRO_0000207532
Regions
	Transmembrane	51 – 71	21	Potential
	Transmembrane	98 – 118	21	Potential
Amino acid modifications
	Glycosylation	45	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P38728-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 236F6CBF54488ED5	FASTA	170	19,812
	10 20 30 40 50 60 MEGRKSEDEK NEAALACDVF ESSNAKLPKN VFRSSFTWYC YEVINRSAFH IWLLLCLTLI 70 80 90 100 110 120 VGWKVFSGIG GRRPSDSNMD GPQTKHKRNP GFLRRHSTIV ILVISLAVSF SWEAFKMYRE 130 140 150 160 170 RTFGKQITQF AKEIIKSAPS TDMESWDRVA ADFNSYMYEN KLWNTEYFFC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae." Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J., Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C., Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M., Davies J., Klis F.M., Robbins P.W., Bussey H. Genetics 147:435-450(1997) [PubMed: 9335584] [Abstract] Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U11583 Genomic DNA. Translation: AAB65055.1.
PIR	S48925.
RefSeq	NP_011820.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4408N.
IntAct	P38728. 3 interactions.
STRING	P38728.
Genome annotation databases
Ensembl	YHL043W; YHL043W; YHL043W; Saccharomyces cerevisiae. [Genome view]
GeneID	856342.
KEGG	sce:YHL043W.
NMPDR	fig|4932.3.peg.2956.
Organism-specific databases
CYGD	YHL043w.
SGD	S000001035. ECM34.
Phylogenomic databases
OrthoDB	EOG91C8DW.
PhylomeDB	P38728.
Gene expression databases
ArrayExpress	P38728.
Genevestigator	P38728.
GermOnline	YHL043W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001142. DUP. [Graphical view]
Pfam	PF00674. DUP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	981769.

Entry information

Entry name

ECM34_YEAST

Accession

Primary (citable) accession number: P38728

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	February 9, 2010
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)