P38728 (ECM34_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein ECM34

Alternative name(s):
Extracellular mutant protein 34

Gene names

Name:	ECM34
Ordered Locus Names:	YHL043W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be involved in cell wall organization and biogenesis.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the DUP/COS family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 170	170	Protein ECM34		PRO_0000207532
Regions
	Transmembrane	51 – 71	21	Helical; Potential
	Transmembrane	98 – 118	21	Helical; Potential
Amino acid modifications
	Glycosylation	45	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P38728 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 236F6CBF54488ED5	FASTA	170	19,812
	10 20 30 40 50 60 MEGRKSEDEK NEAALACDVF ESSNAKLPKN VFRSSFTWYC YEVINRSAFH IWLLLCLTLI 70 80 90 100 110 120 VGWKVFSGIG GRRPSDSNMD GPQTKHKRNP GFLRRHSTIV ILVISLAVSF SWEAFKMYRE 130 140 150 160 170 RTFGKQITQF AKEIIKSAPS TDMESWDRVA ADFNSYMYEN KLWNTEYFFC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae." Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J., Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C., Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M., Davies J., Klis F.M., Robbins P.W., Bussey H. Genetics 147:435-450(1997) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U11583 Genomic DNA. Translation: AAB65055.1. BK006934 Genomic DNA. Translation: DAA06644.1.
PIR	S48925.
RefSeq	NP_011820.1. NM_001179123.1.
3D structure databases
ProteinModelPortal	P38728.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4408N.
IntAct	P38728. 1 interaction.
MINT	MINT-472901.
STRING	4932.YHL043W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHL043W; YHL043W; YHL043W.
GeneID	856342.
KEGG	sce:YHL043W.
Organism-specific databases
CYGD	YHL043w.
SGD	S000001035. ECM34.
Phylogenomic databases
eggNOG	NOG293470.
GeneTree	ENSGT00390000009322.
OrthoDB	EOG4R53D3.
Gene expression databases
Genevestigator	P38728.
GermOnline	YHL043W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001142. DUP. [Graphical view]
Pfam	PF00674. DUP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	981769.

Entry information

Entry name

ECM34_YEAST

Accession

Primary (citable) accession number: P38728
Secondary accession number(s): D3DKS7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program