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Protein

Uncharacterized trans-sulfuration enzyme YHR112C

Gene

YHR112C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 1360 molecules/cell in log phase SD medium.1 Publication

Cofactori

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciYEAST:G3O-31154-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized trans-sulfuration enzyme YHR112C
Gene namesi
Ordered Locus Names:YHR112C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR112C
SGDiS000001154 YHR112C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001147661 – 378Uncharacterized trans-sulfuration enzyme YHR112CAdd BLAST378

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

MaxQBiP38716
PaxDbiP38716
PRIDEiP38716

PTM databases

iPTMnetiP38716

Interactioni

Protein-protein interaction databases

BioGridi36545, 74 interactors
DIPiDIP-2850N
IntActiP38716, 12 interactors
MINTiP38716
STRINGi4932.YHR112C

Structurei

3D structure databases

ProteinModelPortaliP38716
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the trans-sulfuration enzymes family.Curated

Phylogenomic databases

GeneTreeiENSGT00550000075611
HOGENOMiHOG000246415
InParanoidiP38716
OMAiRYSAPNT
OrthoDBiEOG092C2UH2

Family and domain databases

CDDicd00614 CGS_like, 1 hit
Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 1 hit
InterProiView protein in InterPro
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR11808 PTHR11808, 1 hit
PfamiView protein in Pfam
PF01053 Cys_Met_Meta_PP, 1 hit
PIRSFiPIRSF001434 CGS, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00868 CYS_MET_METAB_PP, 1 hit

Sequencei

Sequence statusi: Complete.

P38716-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDLSTALIH GDDKDNRVTD VAPPINVSTT FRYDDDDLIP WTERENLDFM
60 70 80 90 100
EKKPVYSRLA HPNSTRLESI FSEILDGYAV IYSSGLAAFY AAMVHYNPKK
110 120 130 140 150
IFIGQSYHGV RAIANILTRN YGIEQHPLED IEKCASEGDI VHLESPVNPY
160 170 180 190 200
GTSSDIESLA RRAHAKGALL IVDSTFASPP LQYAWNFGAD IVLYSATKYF
210 220 230 240 250
GGHSDLLSGV LVVKEEATSR QLKDDRIYLG TNVANLESFM LLRSLRTYEM
260 270 280 290 300
RITKQSENAT KLVRFLSDHQ SEFDKVLKTI YHSSLQTEEF VKKQLVGGYG
310 320 330 340 350
PVFAITLYTK EQCKQLPLKL KYFHHATSLG GIESLVEWRA MTDPYIDQTL
360 370
IRVSVGCESA NDLIKDLASA LKELQDAA
Length:378
Mass (Da):42,445
Last modified:February 1, 1995 - v1
Checksum:i3300336DCC20EE5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00059 Genomic DNA Translation: AAB68864.1
BK006934 Genomic DNA Translation: DAA06806.1
PIRiS48954
RefSeqiNP_011980.1, NM_001179242.1

Genome annotation databases

EnsemblFungiiYHR112C; YHR112C; YHR112C
GeneIDi856512
KEGGisce:YHR112C

Similar proteinsi

Entry informationi

Entry nameiYHR2_YEAST
AccessioniPrimary (citable) accession number: P38716
Secondary accession number(s): D3DL62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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