P38709 (UGPA2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable UTP--glucose-1-phosphate uridylyltransferase
EC=2.7.7.9

Alternative name(s):
UDP-glucose pyrophosphorylase
Short name=UDPGP
Short name=UGPase

Gene names

Ordered Locus Names:

YHL012W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Plays a central role as a glucosyl donor in cellular metabolic pathways By similarity.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Sequence similarities	Belongs to the UDPGP type 1 family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 493	493	Probable UTP--glucose-1-phosphate uridylyltransferase		PRO_0000185766

Sequences

	Sequence		Length	Mass (Da)
	P38709 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: EFC7FA4A8F681DE2	FASTA	493	56,000
	10 20 30 40 50 60 MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL HIFQRYVLEN 70 80 90 100 110 120 TSITHDLVCD KIRLPIIDEV VELDDIKNYG LLEGKLLSKL AILKLTGKAN PIIGKESPLF 130 140 150 160 170 180 EVKNGMSSLD VIVRQTQNLN VRYNSDVPLI FMTSLETESQ VSNFLEEHYS SSKVRWKTVV 190 200 210 220 230 240 QSSFPQIDKD RLLPIDLQIN SHENDFWYPC GTGNLTDTLY FSGELDKLIA QGKEILFVSN 250 260 270 280 290 300 VDNLGATGDL NILNFIINEK IEYLVEVVER TANVSNTGVL ATYKGKLRSV YYNCLSNESA 310 320 330 340 350 360 STCRIVNTNN IWIDLKKLKV LIESNSLNLP IHSSESKITH KNEEIECLQF KTQLVDCIAF 370 380 390 400 410 420 FPNSRVLKVS RDRFLPLRTC KDLFLLKSTL YDLDSNGTFN LYPLKFGLLP SIDLGDEFAT 430 440 450 460 470 480 YETFKIGVPD IPNILELEHL TVMGNVFFGR NITLKGTVII ICDENDVITV PDGSILENVT 490 IWHKSQLEDM NGY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U11582 Genomic DNA. Translation: AAB65065.1. BK006934 Genomic DNA. Translation: DAA06674.1.
PIR	S46826.
RefSeq	NP_011851.1. NM_001179092.1.
3D structure databases
ProteinModelPortal	P38709.
SMR	P38709. Positions 22-483.
ModBase	Search...
Protein-protein interaction databases
IntAct	P38709. 1 interaction.
STRING	P38709.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHL012W; YHL012W; YHL012W.
GeneID	856374.
KEGG	sce:YHL012W.
NMPDR	fig|4932.3.peg.2991.
Organism-specific databases
CYGD	YHL012w.
SGD	S000001004. YHL012W.
Phylogenomic databases
eggNOG	fuNOG05246.
GeneTree	EFGT00050000004058.
HOGENOM	HBG316482.
Gene expression databases
ArrayExpress	P38709.
Genevestigator	P38709.
GermOnline	YHL012W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002618. UDPGP_trans. IPR016267. UDPGP_trans_subgr. [Graphical view]
KO	K00963.
PANTHER	PTHR11952. UDPGP_trans. 1 hit.
Pfam	PF01704. UDPGP. 1 hit. [Graphical view]
PIRSF	PIRSF000806. UDPGP. 1 hit.
ProtoNet	Search...
Other
NextBio	981858.

Entry information

Entry name

UGPA2_YEAST

Accession

Primary (citable) accession number: P38709
Secondary accession number(s): D3DKQ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program