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P38709

- UGPA2_YEAST

UniProt

P38709 - UGPA2_YEAST

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Protein

Probable UTP--glucose-1-phosphate uridylyltransferase

Gene

YHL012W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Plays a central role as a glucosyl donor in cellular metabolic pathways.By similarity

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

GO - Molecular functioni

  1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. UDP-glucose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Enzyme and pathway databases

ReactomeiREACT_191292. Glycogen synthesis.
REACT_241495. Formation of the active cofactor, UDP-glucuronate.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Short name:
UGPase
Gene namesi
Ordered Locus Names:YHL012W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHL012w.
SGDiS000001004. YHL012W.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Probable UTP--glucose-1-phosphate uridylyltransferasePRO_0000185766Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP38709.

Interactioni

Protein-protein interaction databases

BioGridi36411. 25 interactions.
IntActiP38709. 1 interaction.
STRINGi4932.YHL012W.

Structurei

3D structure databases

ProteinModelPortaliP38709.
SMRiP38709. Positions 23-481.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 1 family.Curated

Phylogenomic databases

eggNOGiCOG4284.
HOGENOMiHOG000113618.
InParanoidiP38709.
KOiK00963.
OMAiINSHEND.
OrthoDBiEOG7HXD0T.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR029044. Nucleotide-diphossugar_trans.
IPR016267. UDPGP_trans.
IPR002618. UDPGP_trans_fam.
[Graphical view]
PANTHERiPTHR11952. PTHR11952. 1 hit.
PTHR11952:SF1. PTHR11952:SF1. 1 hit.
PfamiPF01704. UDPGP. 1 hit.
[Graphical view]
PIRSFiPIRSF000806. UDPGP. 1 hit.
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

P38709-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL
60 70 80 90 100
HIFQRYVLEN TSITHDLVCD KIRLPIIDEV VELDDIKNYG LLEGKLLSKL
110 120 130 140 150
AILKLTGKAN PIIGKESPLF EVKNGMSSLD VIVRQTQNLN VRYNSDVPLI
160 170 180 190 200
FMTSLETESQ VSNFLEEHYS SSKVRWKTVV QSSFPQIDKD RLLPIDLQIN
210 220 230 240 250
SHENDFWYPC GTGNLTDTLY FSGELDKLIA QGKEILFVSN VDNLGATGDL
260 270 280 290 300
NILNFIINEK IEYLVEVVER TANVSNTGVL ATYKGKLRSV YYNCLSNESA
310 320 330 340 350
STCRIVNTNN IWIDLKKLKV LIESNSLNLP IHSSESKITH KNEEIECLQF
360 370 380 390 400
KTQLVDCIAF FPNSRVLKVS RDRFLPLRTC KDLFLLKSTL YDLDSNGTFN
410 420 430 440 450
LYPLKFGLLP SIDLGDEFAT YETFKIGVPD IPNILELEHL TVMGNVFFGR
460 470 480 490
NITLKGTVII ICDENDVITV PDGSILENVT IWHKSQLEDM NGY
Length:493
Mass (Da):56,000
Last modified:February 1, 1995 - v1
Checksum:iEFC7FA4A8F681DE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11582 Genomic DNA. Translation: AAB65065.1.
BK006934 Genomic DNA. Translation: DAA06674.1.
PIRiS46826.
RefSeqiNP_011851.1. NM_001179092.1.

Genome annotation databases

EnsemblFungiiYHL012W; YHL012W; YHL012W.
GeneIDi856374.
KEGGisce:YHL012W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11582 Genomic DNA. Translation: AAB65065.1 .
BK006934 Genomic DNA. Translation: DAA06674.1 .
PIRi S46826.
RefSeqi NP_011851.1. NM_001179092.1.

3D structure databases

ProteinModelPortali P38709.
SMRi P38709. Positions 23-481.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36411. 25 interactions.
IntActi P38709. 1 interaction.
STRINGi 4932.YHL012W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YHL012W ; YHL012W ; YHL012W .
GeneIDi 856374.
KEGGi sce:YHL012W.

Organism-specific databases

CYGDi YHL012w.
SGDi S000001004. YHL012W.

Phylogenomic databases

eggNOGi COG4284.
HOGENOMi HOG000113618.
InParanoidi P38709.
KOi K00963.
OMAi INSHEND.
OrthoDBi EOG7HXD0T.

Enzyme and pathway databases

Reactomei REACT_191292. Glycogen synthesis.
REACT_241495. Formation of the active cofactor, UDP-glucuronate.

Miscellaneous databases

NextBioi 981858.

Gene expression databases

Genevestigatori P38709.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR029044. Nucleotide-diphossugar_trans.
IPR016267. UDPGP_trans.
IPR002618. UDPGP_trans_fam.
[Graphical view ]
PANTHERi PTHR11952. PTHR11952. 1 hit.
PTHR11952:SF1. PTHR11952:SF1. 1 hit.
Pfami PF01704. UDPGP. 1 hit.
[Graphical view ]
PIRSFi PIRSF000806. UDPGP. 1 hit.
SUPFAMi SSF53448. SSF53448. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiUGPA2_YEAST
AccessioniPrimary (citable) accession number: P38709
Secondary accession number(s): D3DKQ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 26, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3