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P38709

- UGPA2_YEAST

UniProt

P38709 - UGPA2_YEAST

Protein

Probable UTP--glucose-1-phosphate uridylyltransferase

Gene

YHL012W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Plays a central role as a glucosyl donor in cellular metabolic pathways.By similarity

    Catalytic activityi

    UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

    GO - Molecular functioni

    1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
    Alternative name(s):
    UDP-glucose pyrophosphorylase
    Short name:
    UDPGP
    Short name:
    UGPase
    Gene namesi
    Ordered Locus Names:YHL012W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHL012w.
    SGDiS000001004. YHL012W.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 493493Probable UTP--glucose-1-phosphate uridylyltransferasePRO_0000185766Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP38709.

    Interactioni

    Protein-protein interaction databases

    BioGridi36411. 25 interactions.
    IntActiP38709. 1 interaction.
    STRINGi4932.YHL012W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38709.
    SMRiP38709. Positions 23-481.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UDPGP type 1 family.Curated

    Phylogenomic databases

    eggNOGiCOG4284.
    HOGENOMiHOG000113618.
    KOiK00963.
    OMAiINSHEND.
    OrthoDBiEOG7HXD0T.

    Family and domain databases

    Gene3Di3.90.550.10. 1 hit.
    InterProiIPR029044. Nucleotide-diphossugar_trans.
    IPR016267. UDPGP_trans.
    IPR002618. UDPGP_trans_fam.
    [Graphical view]
    PANTHERiPTHR11952. PTHR11952. 1 hit.
    PTHR11952:SF1. PTHR11952:SF1. 1 hit.
    PfamiPF01704. UDPGP. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000806. UDPGP. 1 hit.
    SUPFAMiSSF53448. SSF53448. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P38709-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL    50
    HIFQRYVLEN TSITHDLVCD KIRLPIIDEV VELDDIKNYG LLEGKLLSKL 100
    AILKLTGKAN PIIGKESPLF EVKNGMSSLD VIVRQTQNLN VRYNSDVPLI 150
    FMTSLETESQ VSNFLEEHYS SSKVRWKTVV QSSFPQIDKD RLLPIDLQIN 200
    SHENDFWYPC GTGNLTDTLY FSGELDKLIA QGKEILFVSN VDNLGATGDL 250
    NILNFIINEK IEYLVEVVER TANVSNTGVL ATYKGKLRSV YYNCLSNESA 300
    STCRIVNTNN IWIDLKKLKV LIESNSLNLP IHSSESKITH KNEEIECLQF 350
    KTQLVDCIAF FPNSRVLKVS RDRFLPLRTC KDLFLLKSTL YDLDSNGTFN 400
    LYPLKFGLLP SIDLGDEFAT YETFKIGVPD IPNILELEHL TVMGNVFFGR 450
    NITLKGTVII ICDENDVITV PDGSILENVT IWHKSQLEDM NGY 493
    Length:493
    Mass (Da):56,000
    Last modified:February 1, 1995 - v1
    Checksum:iEFC7FA4A8F681DE2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11582 Genomic DNA. Translation: AAB65065.1.
    BK006934 Genomic DNA. Translation: DAA06674.1.
    PIRiS46826.
    RefSeqiNP_011851.1. NM_001179092.1.

    Genome annotation databases

    EnsemblFungiiYHL012W; YHL012W; YHL012W.
    GeneIDi856374.
    KEGGisce:YHL012W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11582 Genomic DNA. Translation: AAB65065.1 .
    BK006934 Genomic DNA. Translation: DAA06674.1 .
    PIRi S46826.
    RefSeqi NP_011851.1. NM_001179092.1.

    3D structure databases

    ProteinModelPortali P38709.
    SMRi P38709. Positions 23-481.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36411. 25 interactions.
    IntActi P38709. 1 interaction.
    STRINGi 4932.YHL012W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHL012W ; YHL012W ; YHL012W .
    GeneIDi 856374.
    KEGGi sce:YHL012W.

    Organism-specific databases

    CYGDi YHL012w.
    SGDi S000001004. YHL012W.

    Phylogenomic databases

    eggNOGi COG4284.
    HOGENOMi HOG000113618.
    KOi K00963.
    OMAi INSHEND.
    OrthoDBi EOG7HXD0T.

    Miscellaneous databases

    NextBioi 981858.

    Gene expression databases

    Genevestigatori P38709.

    Family and domain databases

    Gene3Di 3.90.550.10. 1 hit.
    InterProi IPR029044. Nucleotide-diphossugar_trans.
    IPR016267. UDPGP_trans.
    IPR002618. UDPGP_trans_fam.
    [Graphical view ]
    PANTHERi PTHR11952. PTHR11952. 1 hit.
    PTHR11952:SF1. PTHR11952:SF1. 1 hit.
    Pfami PF01704. UDPGP. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000806. UDPGP. 1 hit.
    SUPFAMi SSF53448. SSF53448. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.

    Entry informationi

    Entry nameiUGPA2_YEAST
    AccessioniPrimary (citable) accession number: P38709
    Secondary accession number(s): D3DKQ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3