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P38690 (YHJ3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein YHR033W
Gene names
Ordered Locus Names:YHR033W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length423 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Ref.4.

Sequence similarities

Belongs to the glutamate 5-kinase family.

Contains 1 PUA domain.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Proline biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processproline biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

RNA binding

Inferred from electronic annotation. Source: InterPro

glutamate 5-kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 423423Uncharacterized protein YHR033W HAMAP-Rule MF_00456
PRO_0000109779

Regions

Domain315 – 40692PUA
Nucleotide binding170 – 1712ATP By similarity
Nucleotide binding214 – 2207ATP By similarity

Sites

Binding site511Substrate By similarity
Binding site1381Substrate By similarity
Binding site1501Substrate; via amide nitrogen By similarity

Experimental info

Sequence conflict1171N → D in AAU09740. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P38690 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: C7CBF7B1773F1981

FASTA42346,864
        10         20         30         40         50         60 
MTKAYTIVIK LGSSSLVDES TKEPKLSIMT LIVETVTNLK RMGHKVIIVS SGGIAVGLDA 

        70         80         90        100        110        120 
LNIPHKPKQL SEVQAIAAVG QGRLIARWNM LFSQYGEQTA QILLTRNDIL RWNQYNNARN 

       130        140        150        160        170        180 
TINELLAMGV IPIVNENDTL SISEIEFGDN DTLSAITAAL VGADFLFLLT DVDCLYTDNP 

       190        200        210        220        230        240 
RTNPDARPIV LVPELSEGLP GVNTSSGSGS EVGTGGMRTK LIAADLASNA GIETIVMKSD 

       250        260        270        280        290        300 
RPEYVPKIVD YIQHHFRPPR HIGNGTQQQF LDLQDTELEQ LRRYDVPMHT KFLANDNKHK 

       310        320        330        340        350        360 
LKNREFWILH GLITKGAIII DENSYDKLLS KDMASLTPNA VIEVRDNFHE LECVDLKIGQ 

       370        380        390        400        410        420 
RLPNGELDIS KPIQSVGCVR SNYTSLELAK IKGLPSEKIH DVLGYSVSEY VAHRENIAFP 


PQF 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Subcellular localization of the yeast proteome."
Kumar A., Agarwal S., Heyman J.A., Matson S., Heidtman M., Piccirillo S., Umansky L., Drawid A., Jansen R., Liu Y., Cheung K.-H., Miller P., Gerstein M., Roeder G.S., Snyder M.
Genes Dev. 16:707-719(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00062 Genomic DNA. Translation: AAB68910.1.
AY723823 Genomic DNA. Translation: AAU09740.1.
BK006934 Genomic DNA. Translation: DAA06724.1.
PIRS46741.
RefSeqNP_011898.1. NM_001179163.1.

3D structure databases

ProteinModelPortalP38690.
SMRP38690. Positions 6-417.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36464. 31 interactions.
DIPDIP-5036N.
IntActP38690. 2 interactions.
MINTMINT-515715.
STRING4932.YHR033W.

Proteomic databases

PaxDbP38690.
PeptideAtlasP38690.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR033W; YHR033W; YHR033W.
GeneID856428.
KEGGsce:YHR033W.

Organism-specific databases

CYGDYHR033w.
SGDS000001075. YHR033W.

Phylogenomic databases

eggNOGCOG0263.
GeneTreeENSGT00550000075661.
HOGENOMHOG000246369.
OMAVSEYVAH.
OrthoDBEOG7SFJ62.

Enzyme and pathway databases

BioCycYEAST:G3O-31093-MONOMER.

Gene expression databases

GenevestigatorP38690.

Family and domain databases

Gene3D2.30.130.10. 1 hit.
3.40.1160.10. 1 hit.
HAMAPMF_00456. ProB.
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. SSF53633. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsTIGR01027. proB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982012.

Entry information

Entry nameYHJ3_YEAST
AccessionPrimary (citable) accession number: P38690
Secondary accession number(s): D3DKY0, Q66R86
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families