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Protein

Uncharacterized protein YHR033W

Gene

YHR033W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei51SubstrateBy similarity1
Binding sitei138SubstrateBy similarity1
Binding sitei150Substrate; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi170 – 171ATPBy similarity2
Nucleotide bindingi214 – 220ATPBy similarity7

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processAmino-acid biosynthesis, Proline biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31093-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YHR033W
Gene namesi
Ordered Locus Names:YHR033W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR033W.
SGDiS000001075. YHR033W.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001097791 – 423Uncharacterized protein YHR033WAdd BLAST423

Proteomic databases

MaxQBiP38690.
PRIDEiP38690.

Interactioni

Protein-protein interaction databases

BioGridi36464. 56 interactors.
DIPiDIP-5036N.
IntActiP38690. 31 interactors.
MINTiMINT-515715.
STRINGi4932.YHR033W.

Structurei

3D structure databases

ProteinModelPortaliP38690.
SMRiP38690.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini315 – 406PUAAdd BLAST92

Sequence similaritiesi

Belongs to the glutamate 5-kinase family.Curated

Phylogenomic databases

GeneTreeiENSGT00550000075661.
HOGENOMiHOG000246369.
InParanoidiP38690.
KOiK00931.
OMAiVSEYVAH.
OrthoDBiEOG092C2KL8.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_00456. ProB. 1 hit.
InterProiView protein in InterPro
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
PfamiView protein in Pfam
PF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
PIRSFiPIRSF000729. GK. 1 hit.
PRINTSiPR00474. GLU5KINASE.
SMARTiView protein in SMART
SM00359. PUA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR01027. proB. 1 hit.
PROSITEiView protein in PROSITE
PS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.

Sequencei

Sequence statusi: Complete.

P38690-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKAYTIVIK LGSSSLVDES TKEPKLSIMT LIVETVTNLK RMGHKVIIVS
60 70 80 90 100
SGGIAVGLDA LNIPHKPKQL SEVQAIAAVG QGRLIARWNM LFSQYGEQTA
110 120 130 140 150
QILLTRNDIL RWNQYNNARN TINELLAMGV IPIVNENDTL SISEIEFGDN
160 170 180 190 200
DTLSAITAAL VGADFLFLLT DVDCLYTDNP RTNPDARPIV LVPELSEGLP
210 220 230 240 250
GVNTSSGSGS EVGTGGMRTK LIAADLASNA GIETIVMKSD RPEYVPKIVD
260 270 280 290 300
YIQHHFRPPR HIGNGTQQQF LDLQDTELEQ LRRYDVPMHT KFLANDNKHK
310 320 330 340 350
LKNREFWILH GLITKGAIII DENSYDKLLS KDMASLTPNA VIEVRDNFHE
360 370 380 390 400
LECVDLKIGQ RLPNGELDIS KPIQSVGCVR SNYTSLELAK IKGLPSEKIH
410 420
DVLGYSVSEY VAHRENIAFP PQF
Length:423
Mass (Da):46,864
Last modified:February 1, 1995 - v1
Checksum:iC7CBF7B1773F1981
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti117N → D in AAU09740 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00062 Genomic DNA. Translation: AAB68910.1.
AY723823 Genomic DNA. Translation: AAU09740.1.
BK006934 Genomic DNA. Translation: DAA06724.1.
PIRiS46741.
RefSeqiNP_011898.1. NM_001179163.1.

Genome annotation databases

EnsemblFungiiYHR033W; YHR033W; YHR033W.
GeneIDi856428.
KEGGisce:YHR033W.

Similar proteinsi

Entry informationi

Entry nameiYHJ3_YEAST
AccessioniPrimary (citable) accession number: P38690
Secondary accession number(s): D3DKY0, Q66R86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 27, 2017
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names