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P38680

- MTR_NEUCR

UniProt

P38680 - MTR_NEUCR

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Protein

N amino acid transport system protein

Gene

mtr

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Required for the transport of neutral aliphatic and aromatic amino acids via the N system.

GO - Biological processi

  1. amino acid transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Protein family/group databases

TCDBi2.A.18.4.1. the amino acid/auxin permease (aaap) family.

Names & Taxonomyi

Protein namesi
Recommended name:
N amino acid transport system protein
Alternative name(s):
Methyltryptophan resistance protein
Gene namesi
Name:mtr
ORF Names:NCU06619
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
ProteomesiUP000001805: Chromosome 4, Linkage Group IV

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470N amino acid transport system proteinPRO_0000093819Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5141.NCU06619.1.

Structurei

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5656ExtracellularSequence AnalysisAdd
BLAST
Topological domaini99 – 13133ExtracellularSequence AnalysisAdd
BLAST
Topological domaini153 – 16816CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini212 – 23625CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini258 – 27518ExtracellularSequence AnalysisAdd
BLAST
Topological domaini297 – 31620CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini338 – 35720ExtracellularSequence AnalysisAdd
BLAST
Topological domaini379 – 3868CytoplasmicSequence Analysis
Topological domaini408 – 42720ExtracellularSequence AnalysisAdd
BLAST
Topological domaini449 – 47022CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei57 – 7721HelicalSequence AnalysisAdd
BLAST
Transmembranei78 – 9821HelicalSequence AnalysisAdd
BLAST
Transmembranei132 – 15221HelicalSequence AnalysisAdd
BLAST
Transmembranei169 – 18921HelicalSequence AnalysisAdd
BLAST
Transmembranei191 – 21121HelicalSequence AnalysisAdd
BLAST
Transmembranei237 – 25721HelicalSequence AnalysisAdd
BLAST
Transmembranei276 – 29621HelicalSequence AnalysisAdd
BLAST
Transmembranei317 – 33721HelicalSequence AnalysisAdd
BLAST
Transmembranei358 – 37821HelicalSequence AnalysisAdd
BLAST
Transmembranei387 – 40721HelicalSequence AnalysisAdd
BLAST
Transmembranei428 – 44821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG126188.
HOGENOMiHOG000158005.
InParanoidiP38680.
OMAiWPKEGTT.
OrthoDBiEOG7RRFHQ.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38680-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSQYETKKN DPNAIMPYPE SNDEHVGEVR GLGGGIMDKE PEAQEGHAKF
60 70 80 90 100
HRLGWKRLTV VLIVEAIALG SLSLPGAFAT LGMVPGVILS VGMGLICIYT
110 120 130 140 150
AHVIGQTKLK HPEIAHYADV GRVMFGRWGY EIISFMFVLQ LIFIVGSHVL
160 170 180 190 200
TGTIMWGTIT DNGNGTCSLV FGIVSAIILF LLAIPPSFAE VAILGYIDFV
210 220 230 240 250
SICAAILITM IATGIRSSHQ EGGLAAVPWS CWPKEDLSLA EGFIAVSNIV
260 270 280 290 300
FAYSFAMCQF SFMDEMHTPS DYKKSIVALG LIEIFIYTVT GGVVYAFVGP
310 320 330 340 350
EVQSPALLSA GPLLAKVAFG IALPVIFISG SINTVVVSRY LIERIWPNNV
360 370 380 390 400
IRYVNTPAGW MVWLGFDFGI TLIAWVIAEA IPFFSDLLAI CSALFISGFS
410 420 430 440 450
FYFPALMYFK ITRNDAKSQG KKYFLDALNM LCFVIGMGIL GIGTYAAIQD
460 470
IMDRYDHGKV SKPYSCAPLA
Length:470
Mass (Da):51,162
Last modified:November 1, 1997 - v2
Checksum:iE8132D1A62373300
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L34605 Genomic DNA. Translation: AAA33600.1.
CM002239 Genomic DNA. Translation: EAA33125.1.
S81767 Genomic DNA. Translation: AAB21410.1.
PIRiS47892.
RefSeqiXP_962361.1. XM_957268.1.
UniGeneiNcr.19075.

Genome annotation databases

EnsemblFungiiEFNCRT00000006380; EFNCRP00000006372; EFNCRG00000006369.
GeneIDi3878509.
KEGGincr:NCU06619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L34605 Genomic DNA. Translation: AAA33600.1 .
CM002239 Genomic DNA. Translation: EAA33125.1 .
S81767 Genomic DNA. Translation: AAB21410.1 .
PIRi S47892.
RefSeqi XP_962361.1. XM_957268.1.
UniGenei Ncr.19075.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5141.NCU06619.1.

Protein family/group databases

TCDBi 2.A.18.4.1. the amino acid/auxin permease (aaap) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii EFNCRT00000006380 ; EFNCRP00000006372 ; EFNCRG00000006369 .
GeneIDi 3878509.
KEGGi ncr:NCU06619.

Phylogenomic databases

eggNOGi NOG126188.
HOGENOMi HOG000158005.
InParanoidi P38680.
OMAi WPKEGTT.
OrthoDBi EOG7RRFHQ.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Spontaneous mutation at the mtr locus in neurospora: the molecular spectrum in wild-type and a mutator strain."
    Dillon D., Stadler D.
    Genetics 138:61-74(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Oak Ridge.
  2. "The genome sequence of the filamentous fungus Neurospora crassa."
    Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.
    , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.
    Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987.
  3. "Sequence and structure of mtr, an amino acid transport gene of Neurospora crassa."
    Koo K., Stuart W.D.
    Genome 34:644-651(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 210-470.

Entry informationi

Entry nameiMTR_NEUCR
AccessioniPrimary (citable) accession number: P38680
Secondary accession number(s): Q7RVG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3