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P38479 (ABP1_SACEX) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Actin-binding protein
Gene names
Name:ABP1
OrganismSaccharomyces exiguus (Yeast)
Taxonomic identifier34358 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKazachstania

Protein attributes

Sequence length617 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be involved in the spatial organization of cell surface growth. An overproduction of ABP1 causes the assembly of the cortical actin skeleton at inappropriate sites on the cell surface, resulting in delocalized surface growth By similarity.

Subcellular location

Cytoplasmcytoskeleton. Note: Cortical cytoskeleton.

Sequence similarities

Contains 1 ADF-H domain.

Contains 1 SH3 domain.

Ontologies

Keywords
   Cellular componentCytoplasm
Cytoskeleton
   DomainRepeat
SH3 domain
   LigandActin-binding
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

cytoskeleton

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 617617Actin-binding protein
PRO_0000064428

Regions

Domain7 – 136130ADF-H
Repeat202 – 211101-1
Repeat444 – 453101-2
Repeat495 – 510162-1
Repeat523 – 538162-2
Domain557 – 61761SH3
Repeat591 – 600101-3
Region202 – 6003993 X 10 AA approximate repeats
Region495 – 538442 X 16 AA repeats of E(7)-A-P-A-P-S-L-P-S-R
Compositional bias486 – 50116Poly-Glu
Compositional bias523 – 5297Poly-Glu

Sequences

Sequence LengthMass (Da)Tools
P38479 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 540A785191B65F85

FASTA61768,420
        10         20         30         40         50         60 
MALEPIDATT HSRDIEQEYQ KVVRGTDNDT TWLIISPNTQ KEYLPSSTGS SFSDFLQSFD 

        70         80         90        100        110        120 
ETKVEYGIAR VSPPGSDVGK IILVGWCPDS APMKTRASFA ANFGTIANSV LPGYHIQVTA 

       130        140        150        160        170        180 
RDEDDLDEEE LLTKISNAAG ARYSIQAAGN SVPTSSASGS APVKKVFTPS LAKKESEPKK 

       190        200        210        220        230        240 
SFVPPPVREE PVPVNVVKDN DADDWDEPEI KERNFETNPL SDNKPAYEPI GKIDLKKVIA 

       250        260        270        280        290        300 
EETAKEDPRL INRIDPSADI AHLKQESKIH RDNDLDNLLK QEKTSSPAVG GTKPPLVNLI 

       310        320        330        340        350        360 
FVEMIIVIRL YKVSRPEKSP AQLWAEKKMK QNQQSDSAQE EQKPVETKTE IEIGVDNSDE 

       370        380        390        400        410        420 
MKIGDLKSRF EKLGAETETE PEPPVQWETD SIPTVVKPQT FGQPAANSKP ATQEVKKPFT 

       430        440        450        460        470        480 
PSNIGQRLPG MHTETPEHEE EDNDDDWGED EDEPPKRNIP PPVMPARESA PQQPLPPRNT 

       490        500        510        520        530        540 
EPEPVEEGEE EEEEEEEEEE EAPAPSLPSR NAAPEPEPEQ PQEEEEEEEA PAPSLPSRGS 

       550        560        570        580        590        600 
VPPPPPQRAV EPEEPAAEAP WATAEYDYEA GEDNELTFAE NDKIINIEFV DDDWWLGELE 

       610 
TTGQKGLFPS NYVVLGN 

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References

[1]"Cloning and sequencing of a gene coding for an actin binding protein of Saccharomyces exiguus."
Lange U., Steiner S., Grolig F., Wagner G., Philippsen P.
Biochim. Biophys. Acta 1217:214-218(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CBS 379.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X73977 Genomic DNA. Translation: CAA52156.1.
PIRS42719.

3D structure databases

ProteinModelPortalP38479.
SMRP38479. Positions 3-141, 559-617.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002108. ADF-H.
IPR001452. SH3_domain.
[Graphical view]
PfamPF00241. Cofilin_ADF. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00102. ADF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
PROSITEPS51263. ADF_H. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABP1_SACEX
AccessionPrimary (citable) accession number: P38479
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families