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P38479

- ABP1_SACEX

UniProt

P38479 - ABP1_SACEX

Protein

Actin-binding protein

Gene

ABP1

Organism
Saccharomyces exiguus (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 1994)
      Previous versions | rss
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    Functioni

    May be involved in the spatial organization of cell surface growth. An overproduction of ABP1 causes the assembly of the cortical actin skeleton at inappropriate sites on the cell surface, resulting in delocalized surface growth By similarity.By similarity

    Keywords - Ligandi

    Actin-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Actin-binding protein
    Gene namesi
    Name:ABP1
    OrganismiSaccharomyces exiguus (Yeast)
    Taxonomic identifieri34358 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKazachstania

    Subcellular locationi

    Cytoplasmcytoskeleton
    Note: Cortical cytoskeleton.

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-KW
    2. cytoskeleton Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 617617Actin-binding proteinPRO_0000064428Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP38479.
    SMRiP38479. Positions 3-141, 559-617.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 136130ADF-HPROSITE-ProRule annotationAdd
    BLAST
    Repeati202 – 211101-1
    Repeati444 – 453101-2
    Repeati495 – 510162-1Add
    BLAST
    Repeati523 – 538162-2Add
    BLAST
    Domaini557 – 61761SH3PROSITE-ProRule annotationAdd
    BLAST
    Repeati591 – 600101-3

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni202 – 6003993 X 10 AA approximate repeatsAdd
    BLAST
    Regioni495 – 538442 X 16 AA repeats of E(7)-A-P-A-P-S-L-P-S-RAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi486 – 50116Poly-GluAdd
    BLAST
    Compositional biasi523 – 5297Poly-Glu

    Sequence similaritiesi

    Contains 1 ADF-H domain.PROSITE-ProRule annotation
    Contains 1 SH3 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, SH3 domain

    Family and domain databases

    Gene3Di3.40.20.10. 1 hit.
    InterProiIPR002108. ADF-H.
    IPR029006. ADF-H/Gelsolin-like_dom.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00241. Cofilin_ADF. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00102. ADF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS51263. ADF_H. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P38479-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALEPIDATT HSRDIEQEYQ KVVRGTDNDT TWLIISPNTQ KEYLPSSTGS    50
    SFSDFLQSFD ETKVEYGIAR VSPPGSDVGK IILVGWCPDS APMKTRASFA 100
    ANFGTIANSV LPGYHIQVTA RDEDDLDEEE LLTKISNAAG ARYSIQAAGN 150
    SVPTSSASGS APVKKVFTPS LAKKESEPKK SFVPPPVREE PVPVNVVKDN 200
    DADDWDEPEI KERNFETNPL SDNKPAYEPI GKIDLKKVIA EETAKEDPRL 250
    INRIDPSADI AHLKQESKIH RDNDLDNLLK QEKTSSPAVG GTKPPLVNLI 300
    FVEMIIVIRL YKVSRPEKSP AQLWAEKKMK QNQQSDSAQE EQKPVETKTE 350
    IEIGVDNSDE MKIGDLKSRF EKLGAETETE PEPPVQWETD SIPTVVKPQT 400
    FGQPAANSKP ATQEVKKPFT PSNIGQRLPG MHTETPEHEE EDNDDDWGED 450
    EDEPPKRNIP PPVMPARESA PQQPLPPRNT EPEPVEEGEE EEEEEEEEEE 500
    EAPAPSLPSR NAAPEPEPEQ PQEEEEEEEA PAPSLPSRGS VPPPPPQRAV 550
    EPEEPAAEAP WATAEYDYEA GEDNELTFAE NDKIINIEFV DDDWWLGELE 600
    TTGQKGLFPS NYVVLGN 617
    Length:617
    Mass (Da):68,420
    Last modified:October 1, 1994 - v1
    Checksum:i540A785191B65F85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X73977 Genomic DNA. Translation: CAA52156.1.
    PIRiS42719.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X73977 Genomic DNA. Translation: CAA52156.1 .
    PIRi S42719.

    3D structure databases

    ProteinModelPortali P38479.
    SMRi P38479. Positions 3-141, 559-617.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.20.10. 1 hit.
    InterProi IPR002108. ADF-H.
    IPR029006. ADF-H/Gelsolin-like_dom.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00241. Cofilin_ADF. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00102. ADF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS51263. ADF_H. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of a gene coding for an actin binding protein of Saccharomyces exiguus."
      Lange U., Steiner S., Grolig F., Wagner G., Philippsen P.
      Biochim. Biophys. Acta 1217:214-218(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: CBS 379.

    Entry informationi

    Entry nameiABP1_SACEX
    AccessioniPrimary (citable) accession number: P38479
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: October 1, 1994
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3