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P38419

- LOXC1_ORYSJ

UniProt

P38419 - LOXC1_ORYSJ

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Protein

Lipoxygenase 7, chloroplastic

Gene
CM-LOX1, LOX2.1, Os08g0508800, LOC_Os08g39840, B1168A08.24
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. This lipoxygenase introduces molecular oxygen exclusively into the C-13 position of linoleic and linolenic acids.1 Publication

Catalytic activityi

Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

Cofactori

Binds 1 iron ion per subunit. Iron is tightly bound By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi581 – 5811Iron; catalytic By similarity
Metal bindingi586 – 5861Iron; catalytic By similarity
Metal bindingi773 – 7731Iron; catalytic By similarity
Metal bindingi777 – 7771Iron; catalytic By similarity
Metal bindingi924 – 9241Iron; via carboxylate; catalytic By similarity

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. linoleate 13S-lipoxygenase activity Source: UniProtKB-EC
  3. phytoene dehydrogenase activity Source: Gramene

GO - Biological processi

  1. lipid oxidation Source: EnsemblPlants/Gramene
  2. oxylipin biosynthetic process Source: UniProtKB-UniPathway
  3. response to other organism Source: Gramene
  4. response to wounding Source: Gramene
Complete GO annotation...

Keywords - Molecular functioni

Dioxygenase, Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16718.
UniPathwayiUPA00382.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoxygenase 7, chloroplastic (EC:1.13.11.12)
Gene namesi
Name:CM-LOX1
Synonyms:LOX2.1
Ordered Locus Names:Os08g0508800, LOC_Os08g39840
ORF Names:B1168A08.24
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 8

Organism-specific databases

GrameneiP38419.

Subcellular locationi

Plastidchloroplast Reviewed prediction

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
  2. plasma membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 6161Chloroplast Reviewed predictionAdd
BLAST
Chaini62 – 924863Lipoxygenase 7, chloroplasticPRO_0000018327Add
BLAST

Proteomic databases

PRIDEiP38419.

Expressioni

Inductioni

By fungal infection.

Structurei

3D structure databases

ProteinModelPortaliP38419.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini88 – 218131PLATAdd
BLAST
Domaini225 – 924700LipoxygenaseAdd
BLAST

Sequence similaritiesi

Belongs to the lipoxygenase family.
Contains 1 PLAT domain.

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiNOG69653.
HOGENOMiHOG000230469.
KOiK00454.
OMAiIARNKMP.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 1 hit.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38419-1 [UniParc]FASTAAdd to Basket

« Hide

MLRPQLNPSS HTTTTSSSSS TQLFASSSCI ASLRRPSSSS SSVVAAARRT    50
RGQGSSRVVV VCASSSATAS RGDSSSDMAA AAAVRVKAVA TIKVTVGELI 100
NRSIDIRDLI GRSLSLELVS SELDAKTGKE KATVRSYAHN VDDDDHSVVT 150
YEADFDVPSG FGPIGAIIVT NELRQEMFLE DINLTASDGA GNSTVLPIRC 200
NSWVQPKSVG DEGTPSKRIF FANKTYLPGQ TPAGLRSYRK NDLQQKRGDG 250
TGEREADDRV YDYDVYNDLG NPDSNGDLAR PVLGGNKQFP YPRRCRTGRP 300
PSKKDPKSET RKGNVYVPRD EEFSPEKEDY FLRKTVGSVL QAAVPAAQSL 350
LLDKLKWNLP FPSFFVIDKL FEDGVELPGV DKLNFLESVV PRLLEHLRDT 400
PAEKILRFET PANIQKDKFA WLRDEEFARE TLAGINPYAI ELVREFPLKS 450
KLDPAVYGPA ESAITADLLE EQMRRVMTVE EAISQKRLFM LDFHDLFLPY 500
VHKIRSLDHT TMYGSRTVFF LTDDGTLQLL AIELTRPASP SQPQWRQVFT 550
PSTDATMSWL WRMAKAHVRA HDAGHHELIT HWLRTHCAVE PYIIAANRQL 600
SEMHPIYQLL RPHFRYTMRI NARARSALIS AGGIIERSFS PQKYSMELSS 650
VAYDKLWRFD TEALPADLVR RGMAEEDPTA EHGLKLAIED YPFANDGLLI 700
WDAIKTWVQA YVARFYPDAD SVAGDEELQA FWTEVRTKGH GDKKDAPWWP 750
KLDSPESLAH TLTTIVWVAA AHHAAVNFGQ YDFGGYFPNR PSIARTVMPV 800
EEPVDGAAME RFLDNPDQAL RECFPSQVQA TVVMAVLDVL SSHSTDEEYL 850
GGEQTRPWNS DAAVQAAYDG FAARLKEIEG VIDGRNKDRK LKNRCGAGIL 900
PYQLMKPFSD SGVTGMGIPN STSI 924
Length:924
Mass (Da):102,819
Last modified:August 30, 2005 - v2
Checksum:iE2142F9775751FEB
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti143 – 1431D → E in AAD39093. 1 Publication
Sequence conflicti342 – 3432AA → P in AAD39093. 1 Publication
Sequence conflicti350 – 3523LLL → CSS in BAA03102. 1 Publication
Sequence conflicti450 – 4501S → T in AAD39093. 1 Publication
Sequence conflicti484 – 4841S → N in BAA03102. 1 Publication
Sequence conflicti540 – 5401P → L in BAA03102. 1 Publication
Sequence conflicti625 – 6284RSAL → ARV in BAA03102. 1 Publication
Sequence conflicti682 – 6821H → Q in BAA03102. 1 Publication
Sequence conflicti764 – 7641T → N in BAA03102. 1 Publication
Sequence conflicti819 – 8191A → R in AAD39093. 1 Publication
Sequence conflicti858 – 8647WNSDAAV → GTATRRL in BAA03102. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D14000 mRNA. Translation: BAA03102.1.
AF095895 mRNA. Translation: AAD39093.1.
AP005816 Genomic DNA. Translation: BAD10665.1.
RefSeqiNP_001062199.1. NM_001068734.1.
UniGeneiOs.4416.

Genome annotation databases

EnsemblPlantsiOS08T0508800-01; OS08T0508800-01; OS08G0508800.
GeneIDi4345993.
KEGGiosa:4345993.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D14000 mRNA. Translation: BAA03102.1 .
AF095895 mRNA. Translation: AAD39093.1 .
AP005816 Genomic DNA. Translation: BAD10665.1 .
RefSeqi NP_001062199.1. NM_001068734.1.
UniGenei Os.4416.

3D structure databases

ProteinModelPortali P38419.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P38419.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS08T0508800-01 ; OS08T0508800-01 ; OS08G0508800 .
GeneIDi 4345993.
KEGGi osa:4345993.

Organism-specific databases

Gramenei P38419.

Phylogenomic databases

eggNOGi NOG69653.
HOGENOMi HOG000230469.
KOi K00454.
OMAi IARNKMP.

Enzyme and pathway databases

UniPathwayi UPA00382 .
BioCyci MetaCyc:MONOMER-16718.

Family and domain databases

Gene3Di 2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProi IPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view ]
PANTHERi PTHR11771. PTHR11771. 1 hit.
Pfami PF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view ]
PRINTSi PR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTi SM00308. LH2. 1 hit.
[Graphical view ]
SUPFAMi SSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEi PS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel lipoxygenase from rice. Primary structure and specific expression upon incompatible infection with rice blast fungus."
    Peng Y.L., Shirano Y., Ohta H., Hibino T., Tanaka K., Shibata D.
    J. Biol. Chem. 269:3755-3761(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
    Strain: cv. Aichiasahi.
    Tissue: Leaf.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLOXC1_ORYSJ
AccessioniPrimary (citable) accession number: P38419
Secondary accession number(s): Q6YVT0, Q9XHM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: August 30, 2005
Last modified: May 14, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi