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P38419 (LOXC1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipoxygenase 7, chloroplastic

EC=1.13.11.12
Gene names
Name:CM-LOX1
Synonyms:LOX2.1
Ordered Locus Names:Os08g0508800, LOC_Os08g39840
ORF Names:B1168A08.24
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length924 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. This lipoxygenase introduces molecular oxygen exclusively into the C-13 position of linoleic and linolenic acids. Ref.1

Catalytic activity

Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.

Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

Cofactor

Binds 1 iron ion per subunit. Iron is tightly bound By similarity.

Pathway

Lipid metabolism; oxylipin biosynthesis.

Subcellular location

Plastidchloroplast Potential.

Induction

By fungal infection.

Sequence similarities

Belongs to the lipoxygenase family.

Contains 1 lipoxygenase domain.

Contains 1 PLAT domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6161Chloroplast Potential
Chain62 – 924863Lipoxygenase 7, chloroplastic
PRO_0000018327

Regions

Domain88 – 218131PLAT
Domain225 – 924700Lipoxygenase

Sites

Metal binding5811Iron; catalytic By similarity
Metal binding5861Iron; catalytic By similarity
Metal binding7731Iron; catalytic By similarity
Metal binding7771Iron; catalytic By similarity
Metal binding9241Iron; via carboxylate; catalytic By similarity

Experimental info

Sequence conflict1431D → E in AAD39093. Ref.1
Sequence conflict342 – 3432AA → P in AAD39093. Ref.1
Sequence conflict350 – 3523LLL → CSS in BAA03102. Ref.1
Sequence conflict4501S → T in AAD39093. Ref.1
Sequence conflict4841S → N in BAA03102. Ref.1
Sequence conflict5401P → L in BAA03102. Ref.1
Sequence conflict625 – 6284RSAL → ARV in BAA03102. Ref.1
Sequence conflict6821H → Q in BAA03102. Ref.1
Sequence conflict7641T → N in BAA03102. Ref.1
Sequence conflict8191A → R in AAD39093. Ref.1
Sequence conflict858 – 8647WNSDAAV → GTATRRL in BAA03102. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P38419 [UniParc].

Last modified August 30, 2005. Version 2.
Checksum: E2142F9775751FEB

FASTA924102,819
        10         20         30         40         50         60 
MLRPQLNPSS HTTTTSSSSS TQLFASSSCI ASLRRPSSSS SSVVAAARRT RGQGSSRVVV 

        70         80         90        100        110        120 
VCASSSATAS RGDSSSDMAA AAAVRVKAVA TIKVTVGELI NRSIDIRDLI GRSLSLELVS 

       130        140        150        160        170        180 
SELDAKTGKE KATVRSYAHN VDDDDHSVVT YEADFDVPSG FGPIGAIIVT NELRQEMFLE 

       190        200        210        220        230        240 
DINLTASDGA GNSTVLPIRC NSWVQPKSVG DEGTPSKRIF FANKTYLPGQ TPAGLRSYRK 

       250        260        270        280        290        300 
NDLQQKRGDG TGEREADDRV YDYDVYNDLG NPDSNGDLAR PVLGGNKQFP YPRRCRTGRP 

       310        320        330        340        350        360 
PSKKDPKSET RKGNVYVPRD EEFSPEKEDY FLRKTVGSVL QAAVPAAQSL LLDKLKWNLP 

       370        380        390        400        410        420 
FPSFFVIDKL FEDGVELPGV DKLNFLESVV PRLLEHLRDT PAEKILRFET PANIQKDKFA 

       430        440        450        460        470        480 
WLRDEEFARE TLAGINPYAI ELVREFPLKS KLDPAVYGPA ESAITADLLE EQMRRVMTVE 

       490        500        510        520        530        540 
EAISQKRLFM LDFHDLFLPY VHKIRSLDHT TMYGSRTVFF LTDDGTLQLL AIELTRPASP 

       550        560        570        580        590        600 
SQPQWRQVFT PSTDATMSWL WRMAKAHVRA HDAGHHELIT HWLRTHCAVE PYIIAANRQL 

       610        620        630        640        650        660 
SEMHPIYQLL RPHFRYTMRI NARARSALIS AGGIIERSFS PQKYSMELSS VAYDKLWRFD 

       670        680        690        700        710        720 
TEALPADLVR RGMAEEDPTA EHGLKLAIED YPFANDGLLI WDAIKTWVQA YVARFYPDAD 

       730        740        750        760        770        780 
SVAGDEELQA FWTEVRTKGH GDKKDAPWWP KLDSPESLAH TLTTIVWVAA AHHAAVNFGQ 

       790        800        810        820        830        840 
YDFGGYFPNR PSIARTVMPV EEPVDGAAME RFLDNPDQAL RECFPSQVQA TVVMAVLDVL 

       850        860        870        880        890        900 
SSHSTDEEYL GGEQTRPWNS DAAVQAAYDG FAARLKEIEG VIDGRNKDRK LKNRCGAGIL 

       910        920 
PYQLMKPFSD SGVTGMGIPN STSI 

« Hide

References

« Hide 'large scale' references
[1]"A novel lipoxygenase from rice. Primary structure and specific expression upon incompatible infection with rice blast fungus."
Peng Y.L., Shirano Y., Ohta H., Hibino T., Tanaka K., Shibata D.
J. Biol. Chem. 269:3755-3761(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
Strain: cv. Aichiasahi.
Tissue: Leaf.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D14000 mRNA. Translation: BAA03102.1.
AF095895 mRNA. Translation: AAD39093.1.
AP005816 Genomic DNA. Translation: BAD10665.1.
RefSeqNP_001062199.1. NM_001068734.1.
UniGeneOs.4416.

3D structure databases

ProteinModelPortalP38419.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP38419.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS08T0508800-01; OS08T0508800-01; OS08G0508800.
GeneID4345993.
KEGGosa:4345993.

Organism-specific databases

GrameneP38419.

Phylogenomic databases

eggNOGNOG69653.
HOGENOMHOG000230469.
KOK00454.
OMAIARNKMP.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-16718.
UniPathwayUPA00382.

Family and domain databases

Gene3D2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_pln.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERPTHR11771. PTHR11771. 1 hit.
PfamPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLOXC1_ORYSJ
AccessionPrimary (citable) accession number: P38419
Secondary accession number(s): Q6YVT0, Q9XHM7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: August 30, 2005
Last modified: May 14, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways