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P38355 (YB8B_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized transporter YBR287W
Gene names
Ordered Locus Names:YBR287W
ORF Names:YBR2034
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Miscellaneous

Present with 6440 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the auxin efflux carrier (TC 2.A.69) family. [View classification]

Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Uncharacterized transporter YBR287W
PRO_0000123805

Regions

Transmembrane10 – 3021Helical; Potential
Transmembrane43 – 6321Helical; Potential
Transmembrane71 – 9121Helical; Potential
Transmembrane253 – 27321Helical; Potential
Transmembrane288 – 30821Helical; Potential
Transmembrane327 – 34721Helical; Potential
Transmembrane358 – 37821Helical; Potential
Transmembrane397 – 41721Helical; Potential

Amino acid modifications

Modified residue1991Phosphothreonine Ref.7
Modified residue2341Phosphoserine Ref.8

Experimental info

Sequence conflict4251N → K in AAT92609. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P38355 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: A2F947D0EA90E41C

FASTA42747,506
        10         20         30         40         50         60 
MVETFSFAHL AYLVFESVLQ VVIIALAGFW SASSGLLPKQ SQKIISLLNV DLFTPCLIFS 

        70         80         90        100        110        120 
KLAKSLSMAK IFEIAIIPIF FGLTTGISFI SGKIMSRILD LDKDETNFVV ANSVFGNSNS 

       130        140        150        160        170        180 
LPVSLTLSLA YTLPNLTWDQ IPNDNRDNVA SRGILYLLIF QQIGQMLRWS WGYNKLMKWS 

       190        200        210        220        230        240 
GENTQHMPPS QVQSLLERTP NIDNEELVNE EQEEQELLEE ENNRMNSSFL SSSSIGDKIW 

       250        260        270        280        290        300 
QKSCTVFERI RANLNPPLYS MIFAVVVAAI GPLQRELFME DGFINNTFAE AVTQLGSVSI 

       310        320        330        340        350        360 
PLILVVLGSN LYPSAEVFPK TVHHSKLLIG SIIGRMILPS CFLLPIIAIA VKYINVSILD 

       370        380        390        400        410        420 
DPIFLVVGFL LTVSPPAIQL TQITQLNEFF EAEMADILFW GYAVLSLPVS IIVVSGAIYV 


LQWANPT 

« Hide

References

« Hide 'large scale' references
[1]"The sequence of a 32,420 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae."
Holmstroem K., Brandt T., Kallesoe T.
Yeast 10:S47-S62(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome II."
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. expand/collapse author list , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[7]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-199, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-234, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X76053 Genomic DNA. Translation: CAA53650.1.
Z36156 Genomic DNA. Translation: CAA85252.1.
AY692590 Genomic DNA. Translation: AAT92609.1.
BK006936 Genomic DNA. Translation: DAA07402.1.
PIRS44549.
RefSeqNP_009846.1. NM_001178635.1.

3D structure databases

ProteinModelPortalP38355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid32981. 23 interactions.
DIPDIP-6660N.
IntActP38355. 6 interactions.
MINTMINT-664487.
STRING4932.YBR287W.

Protein family/group databases

TCDB2.A.69.2.2. the auxin efflux carrier (aec) family.

Proteomic databases

PaxDbP38355.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYBR287W; YBR287W; YBR287W.
GeneID852590.
KEGGsce:YBR287W.

Organism-specific databases

CYGDYBR287w.
SGDS000000491. YBR287W.

Phylogenomic databases

eggNOGCOG0679.
HOGENOMHOG000203886.
KOK07088.
OMAFDVGQEE.
OrthoDBEOG7VQJP2.

Enzyme and pathway databases

BioCycYEAST:G3O-29206-MONOMER.

Gene expression databases

GenevestigatorP38355.

Family and domain databases

InterProIPR004776. Auxin_eff.
[Graphical view]
PfamPF03547. Mem_trans. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio971751.

Entry information

Entry nameYB8B_YEAST
AccessionPrimary (citable) accession number: P38355
Secondary accession number(s): D6VQT2, E9P8W6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: March 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome II

Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families