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P38305

- AIM4_YEAST

UniProt

P38305 - AIM4_YEAST

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Protein
Altered inheritance of mitochondria protein 4
Gene
AIM4, SOY1, YBR194W, YBR1404
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: IntAct
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29136-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Altered inheritance of mitochondria protein 4
Alternative name(s):
Synthetic with old yellow enzyme protein 1
Gene namesi
Name:AIM4
Synonyms:SOY1
Ordered Locus Names:YBR194W
ORF Names:YBR1404
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBR194w.
SGDiS000000398. AIM4.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

Increases frequency of mitochondrial genome loss and sensitivity to freeze-thaw stress and high concentrations of glucose.3 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 123123Altered inheritance of mitochondria protein 4
PRO_0000202507Add
BLAST

Proteomic databases

MaxQBiP38305.
PaxDbiP38305.

Expressioni

Gene expression databases

GenevestigatoriP38305.

Interactioni

Subunit structurei

May interact with the nuclear pore complex.

Binary interactionsi

WithEntry#Exp.IntActNotes
URN1Q065256EBI-20939,EBI-35138

Protein-protein interaction databases

BioGridi32891. 286 interactions.
DIPiDIP-2018N.
IntActiP38305. 67 interactions.
MINTiMINT-401723.
STRINGi4932.YBR194W.

Structurei

3D structure databases

ProteinModelPortaliP38305.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIM4 family.

Phylogenomic databases

eggNOGiNOG80026.
OrthoDBiEOG7KWSWG.

Sequencei

Sequence statusi: Complete.

P38305-1 [UniParc]FASTAAdd to Basket

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MDQKKDPSNN LTERRVSKVQ RPNKKKVRNQ VESLSRNLER NKEGQLLQTV    50
SKGHLEADSG HSLGREKENG ELGIRSIFYD KDWNPRGTAP SHYRNIPYNP 100
ATFKRRTEVQ ARLGNLENIK IPK 123
Length:123
Mass (Da):14,234
Last modified:October 1, 1994 - v1
Checksum:iAF25FE81D22D4C8C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z21487 Genomic DNA. Translation: CAA79681.1.
Z36063 Genomic DNA. Translation: CAA85156.1.
AY692669 Genomic DNA. Translation: AAT92688.1.
BK006936 Genomic DNA. Translation: DAA07308.1.
PIRiS34019.
RefSeqiNP_009753.3. NM_001178542.3.

Genome annotation databases

EnsemblFungiiYBR194W; YBR194W; YBR194W.
GeneIDi852493.
KEGGisce:YBR194W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z21487 Genomic DNA. Translation: CAA79681.1 .
Z36063 Genomic DNA. Translation: CAA85156.1 .
AY692669 Genomic DNA. Translation: AAT92688.1 .
BK006936 Genomic DNA. Translation: DAA07308.1 .
PIRi S34019.
RefSeqi NP_009753.3. NM_001178542.3.

3D structure databases

ProteinModelPortali P38305.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32891. 286 interactions.
DIPi DIP-2018N.
IntActi P38305. 67 interactions.
MINTi MINT-401723.
STRINGi 4932.YBR194W.

Proteomic databases

MaxQBi P38305.
PaxDbi P38305.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YBR194W ; YBR194W ; YBR194W .
GeneIDi 852493.
KEGGi sce:YBR194W.

Organism-specific databases

CYGDi YBR194w.
SGDi S000000398. AIM4.

Phylogenomic databases

eggNOGi NOG80026.
OrthoDBi EOG7KWSWG.

Enzyme and pathway databases

BioCyci YEAST:G3O-29136-MONOMER.

Miscellaneous databases

NextBioi 971483.

Gene expression databases

Genevestigatori P38305.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "RIM2, MSI1 and PGI1 are located within an 8 kb segment of Saccharomyces cerevisiae chromosome II, which also contains the putative ribosomal gene L21 and a new putative essential gene with a leucine zipper motif."
    Demolis N., Mallet L., Bussereau F., Jacquet M.
    Yeast 9:645-659(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "The yeast nuclear pore complex: composition, architecture, and transport mechanism."
    Rout M.P., Aitchison J.D., Suprapto A., Hjertaas K., Zhao Y., Chait B.T.
    J. Cell Biol. 148:635-651(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: ASSOCIATION WITH THE NUCLEAR PORE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  6. "Identification and classification of genes required for tolerance to freeze-thaw stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains."
    Ando A., Nakamura T., Murata Y., Takagi H., Shima J.
    FEMS Yeast Res. 7:244-253(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  7. "Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis."
    Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A.
    PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  8. "Identification of genes required for maximal tolerance to high-glucose concentrations, as those present in industrial alcoholic fermentation media, through a chemogenomics approach."
    Teixeira M.C., Raposo L.R., Palma M., Sa-Correia I.
    OMICS 14:201-210(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiAIM4_YEAST
AccessioniPrimary (citable) accession number: P38305
Secondary accession number(s): D6VQI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

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