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Protein

UPF0303 protein YBR137W

Gene

YBR137W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • posttranslational protein targeting to membrane Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29091-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0303 protein YBR137W
Gene namesi
Ordered Locus Names:YBR137W
ORF Names:YBR1013
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR137W.
SGDiS000000341. YBR137W.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: SGD
  • TRC complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 179179UPF0303 protein YBR137WPRO_0000208926Add
BLAST

Proteomic databases

MaxQBiP38276.
PaxDbiP38276.
PeptideAtlasiP38276.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself1EBI-21630,EBI-21630
NUP116Q026301EBI-21630,EBI-11703
SRP1Q028211EBI-21630,EBI-1797
TEM1P389871EBI-21630,EBI-19113

Protein-protein interaction databases

BioGridi32837. 15 interactions.
DIPiDIP-2038N.
IntActiP38276. 7 interactions.
MINTiMINT-559422.

Structurei

Secondary structure

1
179
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 149Combined sources
Helixi19 – 279Combined sources
Beta strandi30 – 323Combined sources
Helixi36 – 5318Combined sources
Beta strandi54 – 574Combined sources
Beta strandi60 – 645Combined sources
Beta strandi70 – 756Combined sources
Helixi82 – 9817Combined sources
Helixi102 – 1098Combined sources
Turni114 – 1163Combined sources
Turni122 – 1243Combined sources
Beta strandi131 – 1366Combined sources
Turni137 – 1393Combined sources
Beta strandi143 – 1519Combined sources
Helixi154 – 16815Combined sources
Turni169 – 1724Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4CLCX-ray2.80A/B/C/D/E1-179[»]
ProteinModelPortaliP38276.
SMRiP38276. Positions 1-173.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0303 family.Curated

Phylogenomic databases

eggNOGiCOG4702.
HOGENOMiHOG000244036.
InParanoidiP38276.
OMAiTPDNESW.
OrthoDBiEOG7C8GV2.

Family and domain databases

InterProiIPR005624. DUF336.
IPR010371. UPF0303.
[Graphical view]
PfamiPF03928. DUF336. 1 hit.
[Graphical view]
PIRSFiPIRSF008757. UCP008757. 1 hit.

Sequencei

Sequence statusi: Complete.

P38276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVLDKKLLE RLTSRKVPLE ELEDMEKRCF LSTFTYQDAF DLGTYIRNAV
60 70 80 90 100
KENFPEKPVA IDISLPNGHC LFRTVTYGGS ALDNDFWIQR KKKTALRFGH
110 120 130 140 150
SSFYMGCKKG DKTPEEKFFV DSKEYAFHGG AVLIQSERSD YPYACLTISG
160 170
LKQEEDHLMA VSSLIAFANE SLEEDLNLD
Length:179
Mass (Da):20,454
Last modified:July 27, 2011 - v4
Checksum:i8CBA454492E29273
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti110 – 1101G → S in CAA53495 (PubMed:8091856).Curated
Sequence conflicti110 – 1101G → S in CAA85095 (PubMed:7813418).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11088 Genomic DNA. Translation: BAA01861.1.
X75891 Genomic DNA. Translation: CAA53495.1.
Z36006 Genomic DNA. Translation: CAA85095.1.
AY558187 Genomic DNA. Translation: AAS56513.1.
BK006936 Genomic DNA. Translation: DAA07253.2.
PIRiS46006.
RefSeqiNP_009695.2. NM_001178485.2.

Genome annotation databases

EnsemblFungiiYBR137W; YBR137W; YBR137W.
GeneIDi852434.
KEGGisce:YBR137W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11088 Genomic DNA. Translation: BAA01861.1.
X75891 Genomic DNA. Translation: CAA53495.1.
Z36006 Genomic DNA. Translation: CAA85095.1.
AY558187 Genomic DNA. Translation: AAS56513.1.
BK006936 Genomic DNA. Translation: DAA07253.2.
PIRiS46006.
RefSeqiNP_009695.2. NM_001178485.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4CLCX-ray2.80A/B/C/D/E1-179[»]
ProteinModelPortaliP38276.
SMRiP38276. Positions 1-173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32837. 15 interactions.
DIPiDIP-2038N.
IntActiP38276. 7 interactions.
MINTiMINT-559422.

Proteomic databases

MaxQBiP38276.
PaxDbiP38276.
PeptideAtlasiP38276.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR137W; YBR137W; YBR137W.
GeneIDi852434.
KEGGisce:YBR137W.

Organism-specific databases

EuPathDBiFungiDB:YBR137W.
SGDiS000000341. YBR137W.

Phylogenomic databases

eggNOGiCOG4702.
HOGENOMiHOG000244036.
InParanoidiP38276.
OMAiTPDNESW.
OrthoDBiEOG7C8GV2.

Enzyme and pathway databases

BioCyciYEAST:G3O-29091-MONOMER.

Miscellaneous databases

NextBioi971321.
PROiP38276.

Family and domain databases

InterProiIPR005624. DUF336.
IPR010371. UPF0303.
[Graphical view]
PfamiPF03928. DUF336. 1 hit.
[Graphical view]
PIRSFiPIRSF008757. UCP008757. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae."
    Kato R., Ogawa H.
    Nucleic Acids Res. 22:3104-3112(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The sequence of 29.7 kb from the right arm of chromosome II reveals 13 complete open reading frames, of which ten correspond to new genes."
    Becam A.-M., Cullin C., Grzybowska E., Lacroute F., Nasr F., Ozier-Kalogeropoulos O., Palucha A., Slonimski P.P., Zagulski M., Herbert C.J.
    Yeast 10:S1-S11(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 110.
    Strain: ATCC 204508 / S288c.
  5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYBY7_YEAST
AccessioniPrimary (citable) accession number: P38276
Secondary accession number(s): D6VQD3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 27, 2011
Last modified: July 22, 2015
This is version 110 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1200 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.