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Protein

UPF0303 protein YBR137W

Gene

YBR137W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 1200 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • posttranslational protein targeting to endoplasmic reticulum membrane Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-29091-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0303 protein YBR137W
Gene namesi
Ordered Locus Names:YBR137W
ORF Names:YBR1013
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR137W.
SGDiS000000341. YBR137W.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002089261 – 179UPF0303 protein YBR137WAdd BLAST179

Proteomic databases

MaxQBiP38276.
PRIDEiP38276.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SGT2Q121183EBI-21630,EBI-31784

Protein-protein interaction databases

BioGridi32837. 74 interactors.
DIPiDIP-2038N.
IntActiP38276. 10 interactors.
MINTiMINT-559422.
STRINGi4932.YBR137W.

Structurei

Secondary structure

1179
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 14Combined sources9
Helixi19 – 27Combined sources9
Beta strandi30 – 32Combined sources3
Helixi36 – 53Combined sources18
Beta strandi54 – 57Combined sources4
Beta strandi60 – 64Combined sources5
Beta strandi70 – 75Combined sources6
Helixi82 – 98Combined sources17
Helixi102 – 109Combined sources8
Turni114 – 116Combined sources3
Turni122 – 124Combined sources3
Beta strandi131 – 136Combined sources6
Turni137 – 139Combined sources3
Beta strandi143 – 151Combined sources9
Helixi154 – 168Combined sources15
Turni169 – 172Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4CLCX-ray2.80A/B/C/D/E1-179[»]
ProteinModelPortaliP38276.
SMRiP38276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0303 family.Curated

Phylogenomic databases

HOGENOMiHOG000244036.
InParanoidiP38276.
OMAiLPQRDDH.
OrthoDBiEOG092C4T1Q.

Family and domain databases

InterProiView protein in InterPro
IPR005624. Haem_degrading.
IPR010371. UPF0303.
PfamiView protein in Pfam
PF03928. Haem_degrading. 1 hit.
PIRSFiPIRSF008757. UCP008757. 1 hit.

Sequencei

Sequence statusi: Complete.

P38276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVLDKKLLE RLTSRKVPLE ELEDMEKRCF LSTFTYQDAF DLGTYIRNAV
60 70 80 90 100
KENFPEKPVA IDISLPNGHC LFRTVTYGGS ALDNDFWIQR KKKTALRFGH
110 120 130 140 150
SSFYMGCKKG DKTPEEKFFV DSKEYAFHGG AVLIQSERSD YPYACLTISG
160 170
LKQEEDHLMA VSSLIAFANE SLEEDLNLD
Length:179
Mass (Da):20,454
Last modified:July 27, 2011 - v4
Checksum:i8CBA454492E29273
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti110G → S in CAA53495 (PubMed:8091856).Curated1
Sequence conflicti110G → S in CAA85095 (PubMed:7813418).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11088 Genomic DNA. Translation: BAA01861.1.
X75891 Genomic DNA. Translation: CAA53495.1.
Z36006 Genomic DNA. Translation: CAA85095.1.
AY558187 Genomic DNA. Translation: AAS56513.1.
BK006936 Genomic DNA. Translation: DAA07253.2.
PIRiS46006.
RefSeqiNP_009695.2. NM_001178485.2.

Genome annotation databases

EnsemblFungiiYBR137W; YBR137W; YBR137W.
GeneIDi852434.
KEGGisce:YBR137W.

Similar proteinsi

Entry informationi

Entry nameiYBY7_YEAST
AccessioniPrimary (citable) accession number: P38276
Secondary accession number(s): D6VQD3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 27, 2011
Last modified: September 27, 2017
This is version 125 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names