P38268 (YBW6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein YBR116C

Gene names

Ordered Locus Names:	YBR116C
ORF Names:	YBR0911

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Induction	Highly induced during the diauxic shift or during carbon-limited growth, and also induced by mild heat stress. Ref.4 Ref.5 Ref.6
Caution	Product of a dubious gene prediction. Partially overlaps TKL2.

Ontologies

Keywords
Biological process	Stress response
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 175	175	Putative uncharacterized protein YBR116C		PRO_0000202488
Regions
	Transmembrane	143 – 166	24	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P38268 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 6CF72CC0909E055E	FASTA	175	20,215
	10 20 30 40 50 60 MQPKNCTILK KSKQELFPCQ TFILLTGKVK NTDSLFYQTV FRSCPLKYWL LQAGVSMLIN 70 80 90 100 110 120 RSDSTNLVVQ ARGLKFTNCS ISQRTVLRQG LKRQSITTKE SSCFLLWEEL SKSEEVNSSL 130 140 150 160 170 LFHTSWLMVT CCLKYIYMYD ICTCFLFCAF VTSIFIETDY SIFFLLTASR GIAQF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of a 70 kb region on the right arm of yeast chromosome II." Mannhaupt G., Stucka R., Ehnle S., Vetter I., Feldmann H. Yeast 10:1363-1381(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Dissecting the regulatory circuitry of a eukaryotic genome." Holstege F.C.P., Jennings E.G., Wyrick J.J., Lee T.I., Hengartner C.J., Green M.R., Golub T.R., Lander E.S., Young R.A. Cell 95:717-728(1998) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
[5]	"Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae." Sakaki K., Tashiro K., Kuhara S., Mihara K. J. Biochem. 134:373-384(2003) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
[6]	"The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur." Boer V.M., de Winde J.H., Pronk J.T., Piper M.D.W. J. Biol. Chem. 278:3265-3274(2003) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X78993 Genomic DNA. Translation: CAA55618.1. Z35985 Genomic DNA. Translation: CAA85073.1. AY693259 Genomic DNA. Translation: AAT93278.1.
PIR	S48280.
3D structure databases
ProteinModelPortal	P38268.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2743N.
IntAct	P38268. 1 interaction.
MINT	MINT-533177.
STRING	4932.YBR116C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YBR116C; YBR116C; YBR116C.
Organism-specific databases
SGD	S000000320. YBR116C.
Gene expression databases
Genevestigator	P38268.
GermOnline	YBR116C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

YBW6_YEAST

Accession

Primary (citable) accession number: P38268

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program