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Reviewed, UniProtKB/Swiss-Prot P38266 (YBV8_YEAST)

Last modified June 16, 2009. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Uncharacterized protein YBR108W
Gene names
Ordered Locus Names: YBR108W
ORF Names: YBR0901
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length947 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Subunit structure

Interacts with RVS167. Ref.4

Sequence caution

The sequence CAA55611.1 differs from that shown. Reason: Frameshift at position 841.

The sequence CAA85063.1 differs from that shown. Reason: Frameshift at position 841.

Ontologies

Keywords
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 947947Uncharacterized protein YBR108W
PRO_0000202486

Regions

Compositional bias95 – 398304Gln-rich
Compositional bias371 – 44777Pro-rich
Compositional bias862 – 90746Pro-rich

Amino acid modifications

Modified residue571Phosphoserine Ref.8
Modified residue581Phosphoserine Ref.8
Modified residue641Phosphoserine Ref.8
Modified residue4761Phosphoserine Ref.8
Modified residue6691Phosphoserine Ref.7
Modified residue7291Phosphothreonine Ref.8 Ref.6
Modified residue8051Phosphothreonine Ref.7 Ref.5
Modified residue8261Phosphothreonine Ref.6
Modified residue8421Phosphoserine Ref.8 Ref.7
Modified residue8431Phosphoserine Ref.8 Ref.7
Modified residue8471Phosphoserine Ref.8
Modified residue8611Phosphothreonine Ref.8
Modified residue9141Phosphotyrosine Ref.8
Modified residue9151Phosphoserine Ref.8 Ref.5
Modified residue9191Phosphoserine Ref.8

Sequences

Sequence LengthMass (Da)Tools
P38266-1 [UniParc].

Last modified September 13, 2005. Version 2.
Checksum: AB58F141D3E14BB7

FASTA947103,835
        10         20         30         40         50         60 
MGFWENNKDS ITSGLKSAGK YGYQGTKYVA KTGYKASKKH YNNSKARRER KSGKKNSSDE 

        70         80         90        100        110        120 
EYDSEDEMEY ERKPTDIRSL KDPKSFPPPP LKPGQKTYTG QQQQQMPNGQ ASYAFQGAYQ 

       130        140        150        160        170        180 
GQPGAGSTEQ SQYAQPQYNQ YPQQQLQQGV MPQQQQLQQG VVPQQPPIYG EQVPPYGSNS 

       190        200        210        220        230        240 
NATSYQSLPQ QNQPQNAIPS QVSLNSASQQ STGFVSQNLQ YGTQSSNPAP SPSFQNGLQC 

       250        260        270        280        290        300 
HQQPQYVSHG STNLGQSQFP SGQQQQPTTQ FGQQVLPSPA QPQQQQQGQP LPPPRGQVIL 

       310        320        330        340        350        360 
PAPGEPLSNG FGQQQQQQQQ QQQPLNQNNA LLPQMNVEGV SGMAAVQPVY GQAMSSTTNM 

       370        380        390        400        410        420 
QDSNPSYGAS PMQGQPPVGG QPPVPVRMQP QPPQPMQQGN IYPIEPSLDS TGSTPHFEVT 

       430        440        450        460        470        480 
PFDPDAPAPK PKIDIPTVDV SSLPPPPTHR DRGAVVHQEP APSGKIQPNT TSSAASLPAK 

       490        500        510        520        530        540 
HSRTTTADNE RNSGNKENDE STSKSSILGH YDVDANIMPP PKPFRHGLDS VPSEHTTKNA 

       550        560        570        580        590        600 
PERAVPILPP RNNVEPPPPP SRGNFERTES VLSTNAANVQ EDPISNFLPP PKPFRHTETK 

       610        620        630        640        650        660 
QNQNSKASPV EMKGEVLPGH PSEEDRNVEP SLVPQSKPQS QSQFRRAHME TQPIQNFQPP 

       670        680        690        700        710        720 
PKPFRRSQSS NSSDSSYTID GPEANHGRGR GRIAKHHDGD EYNPKSENST ENGRLGDAPN 

       730        740        750        760        770        780 
SFIRKRAPTP PAPSRSEKLH EGTITSEVDS SKDANKYEKS IPPVTSSIQA QQSTKKAPPP 

       790        800        810        820        830        840 
VVKPKPRNFS LKANEYPKEL TREATGQDEV LNSITNELSH IKLRKTNVNL EKLGGSKKVK 

       850        860        870        880        890        900 
DSSPVPSDLD EKYVSASGSI TPPRPPPSRS SPKKVPPVVP KKNDNLKKKP PVVPKKKPLL 

       910        920        930        940 
KSLEPRPIEM ERAYSGDISA ADDNLNPFER YKRNVVPQED DRLHKLK 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of a 70 kb region on the right arm of yeast chromosome II."
Mannhaupt G., Stucka R., Ehnle S., Vetter I., Feldmann H.
Yeast 10:1363-1381(1994) [PubMed: 7900426] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome II."
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. expand/collapse author list , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Sequencing and comparison of yeast species to identify genes and regulatory elements."
Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
Nature 423:241-254(2003) [PubMed: 12748633] [Abstract]
Cited for: IDENTIFICATION OF FRAMESHIFT.
[4]"Characterizing the sphingolipid signaling pathway that remediates defects associated with loss of the yeast amphiphysin-like orthologs, Rvs161p and Rvs167p."
Germann M., Swain E., Bergman L., Nickels J.T. Jr.
J. Biol. Chem. 280:4270-4278(2005) [PubMed: 15561700] [Abstract]
Cited for: INTERACTION WITH RVS167.
[5]"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway."
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N.
Mol. Cell. Proteomics 4:310-327(2005) [PubMed: 15665377] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-805 AND SER-915, MASS SPECTROMETRY.
[6]"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed: 17287358] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-729 AND THR-826, MASS SPECTROMETRY.
[7]"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases."
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-669; THR-805; SER-842 AND SER-843, MASS SPECTROMETRY.
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-57; SER-58; SER-64; SER-476; THR-729; SER-842; SER-843; SER-847; THR-861; TYR-914; SER-915 AND SER-919, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

X78993 Genomic DNA. Translation: CAA55611.1. Frameshift.
Z35977 Genomic DNA. Translation: CAA85063.1. Frameshift.
PIRS48273.
RefSeqNP_009666.2.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:1602N.
IntActP38266. 6 interactions.

Proteomic databases

PeptideAtlasP38266.

Genome annotation databases

EnsemblYBR108W. Saccharomyces cerevisiae. [Contig view]
GeneID852405.
GenomeReviewsGene locus YBR108W in contig Y13134_GR.
KEGGsce:YBR108W.
NMPDRfig|4932.3.peg.365.

Organism-specific databases

CYGDYBR108w.
SGDS000000312. YBR108W.
Yeast-GFPSearch...

Phylogenomic databases

HOGENOMP38266.
OMAP38266. PPKPFRR.

Gene expression databases

ArrayExpressP38266.
GermOnlineYBR108W. Saccharomyces cerevisiae.

Family and domain databases

ProtoNetSearch...

Other Resources

NextBio971246.

Entry information

Entry nameYBV8_YEAST
AccessionPrimary (citable) accession number: P38266
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: September 13, 2005
Last modified: June 16, 2009
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome II

Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents