P38239 (YBR2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized RING finger protein YBR062C

Gene names

Ordered Locus Names:	YBR062C
ORF Names:	YBR0528

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	Present with 195 molecules/cell in log phase SD medium.
Sequence similarities	Contains 1 RING-type zinc finger.
Sequence caution	The sequence CAA85005.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAA85005.1 differs from that shown. Reason: Frameshift at position 33.

Ontologies

Keywords
Domain	Zinc-finger
Ligand	Metal-binding Zinc
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Uncharacterized RING finger protein YBR062C		PRO_0000056335
Regions
	Zinc finger	109 – 153	45	RING-type
Amino acid modifications
	Modified residue	56	1	Phosphoserine Ref.5

Sequences

	Sequence		Length	Mass (Da)
	P38239 [UniParc]. Last modified September 13, 2005. Version 2. Checksum: 858ECAAC97F48809	FASTA	180	20,596
	10 20 30 40 50 60 MSTYEEEHGI QQNSRDYQEV GGTSQEEQRR QVRSQLQGLF QNFGNTSGEG DAHSDSTLLL 70 80 90 100 110 120 RLLSQMLPES LQEEWLQEMD KGKSAGCPDT FAASLPRINK KKLKATDNCS ICYTNYLEDE 130 140 150 160 170 180 YPLVVELPHC HHKFDLECLS VWLSRSTTCP LCRDNVMGHR IINEIDTTEA ELEEDWGMYG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Finding functional features in Saccharomyces genomes by phylogenetic footprinting." Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J., Waterston R., Cohen B.A., Johnston M. Science 301:71-76(2003) [PubMed] [Europe PMC] [Abstract] Cited for: REVISION OF GENE MODEL.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-56, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z35931 Genomic DNA. Translation: CAA85005.1. Sequence problems. BK006936 Genomic DNA. Translation: DAA07182.1.
PIR	S45920.
RefSeq	NP_009618.2. NM_001178410.1.
3D structure databases
ProteinModelPortal	P38239.
SMR	P38239. Positions 109-153.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-2493203.
STRING	4932.YBR062C.
Proteomic databases
PaxDb	P38239.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YBR062C; YBR062C; YBR062C.
GeneID	852354.
KEGG	sce:YBR062C.
Organism-specific databases
CYGD	YBR062c.
SGD	S000000266. YBR062C.
Phylogenomic databases
eggNOG	NOG258882.
HOGENOM	HOG000214894.
OMA	LEEDWGM.
OrthoDB	EOG4D2B07.
Gene expression databases
Genevestigator	P38239.
GermOnline	YBR062C. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF13639. zf-RING_2. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. [Graphical view]
PROSITE	PS00518. ZF_RING_1. False negative. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	971110.

Entry information

Entry name

YBR2_YEAST

Accession

Primary (citable) accession number: P38239
Secondary accession number(s): D6VQ62

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	September 13, 2005
Last modified:	May 1, 2013
This is version 90 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program