Reviewed, UniProtKB/Swiss-Prot P38230 (QOR_YEAST)

Names and origin

Protein names

Recommended name:
    Probable quinone oxidoreductase
    EC=1.6.5.5
Alternative name(s):
    NADPH:quinone reductase

Gene names

Name:	ZTA1
Ordered Locus Names:	YBR046C
ORF Names:	YBR0421

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	NADPH + 2 quinone = NADP(+) + 2 semiquinone.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Ontologies

Keywords
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: InterPro response to oxidative stress Inferred from mutant phenotype. Source: SGD
Cellular component	cytoplasm Inferred from direct assay. Source: SGD nucleus Inferred from direct assay. Source: SGD
Molecular function	AU-rich element binding Inferred from direct assay. Source: SGD NADPH:quinone reductase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	Probable quinone oxidoreductase		PRO_0000160912

Sequences

	Sequence		Length	Mass (Da)
	P38230-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 8E9D2D85D9AC518E	FASTA	334	37,019
	10 20 30 40 50 60 MKCTIPEQQK VILIDEIGGY DVIKYEDYPV PSISEEELLI KNKYTGVNYI ESYFRKGIYP 70 80 90 100 110 120 CEKPYVLGRE ASGTVVAKGK GVTNFEVGDQ VAYISNSTFA QYSKISSQGP VMKLPKGTSD 130 140 150 160 170 180 EELKLYAAGL LQVLTALSFT NEAYHVKKGD YVLLFAAAGG VGLILNQLLK MKGAHTIAVA 190 200 210 220 230 240 STDEKLKIAK EYGAEYLINA SKEDILRQVL KFTNGKGVDA SFDSVGKDTF EISLAALKRK 250 260 270 280 290 300 GVFVSFGNAS GLIPPFSITR LSPKNITLVR PQLYGYIADP EEWKYYSDEF FGLVNSKKLN 310 320 330 IKIYKTYPLR DYRTAAADIE SRKTVGKLVL EIPQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z35915 Genomic DNA. Translation: CAA84988.1. AY557866 Genomic DNA. Translation: AAS56192.1.
PIR	S45904.
RefSeq	NP_009602.1.
3D structure databases
HSSP	HSSP built from PDB template 1QOR based on UniProtKB P28304.
ModBase	Search...
Proteomic databases
PeptideAtlas	P38230.
Genome annotation databases
Ensembl	YBR046C. Saccharomyces cerevisiae. [Contig view]
GeneID	852335.
GenomeReviews	Gene locus YBR046C in contig Y13134_GR.
KEGG	sce:YBR046C.
NMPDR	fig|4932.3.peg.297.
Organism-specific databases
CYGD	YBR046c.
SGD	S000000250. ZTA1.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P38230.
Gene expression databases
ArrayExpress	P38230.
GermOnline	YBR046C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR013154. AlcDHase_GroES-like. IPR002085. AlcDHase_SF_Zn. IPR013149. AlcDHase_Zn-bd. IPR016040. NAD(P)-bd. IPR002364. Quin_OxRdtase/zeta-crystal_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
PROSITE	PS01162. QOR_ZETA_CRYSTAL. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
LinkHub	P38230.
NextBio	971058.

Entry information

Entry name

QOR_YEAST

Accession

Primary (citable) accession number: P38230

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	November 25, 2008
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)