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P38192 (RRT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative regulator of rDNA transcription protein 1
Gene names
Name:RRT1
Ordered Locus Names:YBL048W
ORF Names:YBL0519
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length103 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Identified in a screen for mutants with decreased levels of rDNA transcription.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Induction

By the zinc-responsive transcription factor ZAP1 in response to zinc deficiency and by mild heat stress. Ref.5 Ref.6

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 103103Putative regulator of rDNA transcription protein 1
PRO_0000202456

Regions

Transmembrane9 – 3325Helical; Potential
Transmembrane40 – 5718Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P38192 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 43264FBB6BE4A0C3

FASTA10312,447
        10         20         30         40         50         60 
MILFKNLVFL PSILIGYISI RVSLLVWVNW VLVWSSCFQV AFIFSLWYFI LSIYTFFYSK 

        70         80         90        100 
KIKQIISYEP SYFVFSYRAI DLCPERVLLY FFCIFNNVVF PML 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes."
Scherens B., el Bakkoury M., Vierendeels F., Dubois E., Messenguy F.
Yeast 9:1355-1371(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome II."
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. expand/collapse author list , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast."
Lyons T.J., Gasch A.P., Gaither L.A., Botstein D., Brown P.O., Eide D.J.
Proc. Natl. Acad. Sci. U.S.A. 97:7957-7962(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
[6]"Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae."
Sakaki K., Tashiro K., Kuhara S., Mihara K.
J. Biochem. 134:373-384(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
[7]"Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae."
Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S.
Genetics 182:105-119(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE NAME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z23261 Genomic DNA. No translation available.
Z35809 Genomic DNA. Translation: CAA84868.1.
AY693312 Genomic DNA. Translation: AAT93331.1.
BK006936 Genomic DNA. No translation available.
PIRS45783.

3D structure databases

ProteinModelPortalP38192.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP38192. 1 interaction.
MINTMINT-2493123.
STRING4932.YBL048W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYBL048W; YBL048W; YBL048W.

Organism-specific databases

CYGDYBL048w.
SGDS000000144. RRT1.

Gene expression databases

GenevestigatorP38192.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameRRT1_YEAST
AccessionPrimary (citable) accession number: P38192
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome II

Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD