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Protein

Putative regulator of rDNA transcription protein 1

Gene

RRT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Identified in a screen for mutants with decreased levels of rDNA transcription.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative regulator of rDNA transcription protein 1
Gene namesi
Name:RRT1
Ordered Locus Names:YBL048W
ORF Names:YBL0519
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBL048w.
SGDiS000000144. RRT1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 3325HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 5718HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 103103Putative regulator of rDNA transcription protein 1PRO_0000202456Add
BLAST

Expressioni

Inductioni

By the zinc-responsive transcription factor ZAP1 in response to zinc deficiency and by mild heat stress.2 Publications

Gene expression databases

GenevestigatoriP38192.

Interactioni

Protein-protein interaction databases

IntActiP38192. 1 interaction.
MINTiMINT-2493123.
STRINGi4932.YBL048W.

Structurei

3D structure databases

ProteinModelPortaliP38192.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Sequencei

Sequence statusi: Complete.

P38192-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MILFKNLVFL PSILIGYISI RVSLLVWVNW VLVWSSCFQV AFIFSLWYFI
60 70 80 90 100
LSIYTFFYSK KIKQIISYEP SYFVFSYRAI DLCPERVLLY FFCIFNNVVF

PML
Length:103
Mass (Da):12,447
Last modified:October 1, 1994 - v1
Checksum:i43264FBB6BE4A0C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z23261 Genomic DNA. No translation available.
Z35809 Genomic DNA. Translation: CAA84868.1.
AY693312 Genomic DNA. Translation: AAT93331.1.
BK006936 Genomic DNA. No translation available.
PIRiS45783.

Genome annotation databases

EnsemblFungiiYBL048W; YBL048W; YBL048W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z23261 Genomic DNA. No translation available.
Z35809 Genomic DNA. Translation: CAA84868.1.
AY693312 Genomic DNA. Translation: AAT93331.1.
BK006936 Genomic DNA. No translation available.
PIRiS45783.

3D structure databases

ProteinModelPortaliP38192.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP38192. 1 interaction.
MINTiMINT-2493123.
STRINGi4932.YBL048W.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBL048W; YBL048W; YBL048W.

Organism-specific databases

CYGDiYBL048w.
SGDiS000000144. RRT1.

Gene expression databases

GenevestigatoriP38192.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes."
    Scherens B., el Bakkoury M., Vierendeels F., Dubois E., Messenguy F.
    Yeast 9:1355-1371(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast."
    Lyons T.J., Gasch A.P., Gaither L.A., Botstein D., Brown P.O., Eide D.J.
    Proc. Natl. Acad. Sci. U.S.A. 97:7957-7962(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  6. "Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae."
    Sakaki K., Tashiro K., Kuhara S., Mihara K.
    J. Biochem. 134:373-384(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  7. "Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae."
    Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S.
    Genetics 182:105-119(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.

Entry informationi

Entry nameiRRT1_YEAST
AccessioniPrimary (citable) accession number: P38192
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: January 7, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Product of a dubious gene prediction.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.