Reviewed, UniProtKB/Swiss-Prot P38192 (YBE8_YEAST)

Names and origin

Protein names

Recommended name:
    Putative uncharacterized protein YBL048W

Gene names

Ordered Locus Names:	YBL048W
ORF Names:	YBL0519

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	103 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Induction	By the zinc-responsive transcription factor ZAP1 in response to zinc deficiency and by mild heat stress. Ref.4 Ref.5

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 103	103	Putative uncharacterized protein YBL048W		PRO_0000202456
Regions
	Transmembrane	9 – 33	25	Potential
	Transmembrane	40 – 57	18	Potential

Sequences

	Sequence		Length	Mass (Da)
	P38192-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 43264FBB6BE4A0C3	FASTA	103	12,447
	10 20 30 40 50 60 MILFKNLVFL PSILIGYISI RVSLLVWVNW VLVWSSCFQV AFIFSLWYFI LSIYTFFYSK 70 80 90 100 KIKQIISYEP SYFVFSYRAI DLCPERVLLY FFCIFNNVVF PML

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes." Scherens B., el Bakkoury M., Vierendeels F., Dubois E., Messenguy F. Yeast 9:1355-1371(1993) [PubMed: 8154187] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast." Lyons T.J., Gasch A.P., Gaither L.A., Botstein D., Brown P.O., Eide D.J. Proc. Natl. Acad. Sci. U.S.A. 97:7957-7962(2000) [PubMed: 10884426] [Abstract] Cited for: INDUCTION.
[5]	"Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae." Sakaki K., Tashiro K., Kuhara S., Mihara K. J. Biochem. 134:373-384(2003) [PubMed: 14561723] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z23261 Genomic DNA. No translation available. Z35809 Genomic DNA. Translation: CAA84868.1. AY693312 Genomic DNA. Translation: AAT93331.1.
PIR	S45783.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P38192. 1 interaction.
STRING	P38192.
Genome annotation databases
Ensembl	YBL048W; YBL048W; YBL048W; Saccharomyces cerevisiae. [Genome view]
Organism-specific databases
CYGD	YBL048w.
SGD	S000000144. YBL048W.
Gene expression databases
ArrayExpress	P38192.
Genevestigator	P38192.
GermOnline	YBL048W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

YBE8_YEAST

Accession

Primary (citable) accession number: P38192

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	October 13, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)