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P38176

- AVT5_YEAST

UniProt

P38176 - AVT5_YEAST

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Protein

Vacuolar amino acid transporter 5

Gene

AVT5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Probable amino acid transporter of unknown specificity.1 Publication

GO - Molecular functioni

  1. transporter activity Source: SGD

GO - Biological processi

  1. amino acid transport Source: UniProtKB-KW
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-28978-MONOMER.

Protein family/group databases

TCDBi2.A.18.6.10. the amino acid/auxin permease (aaap) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar amino acid transporter 5
Gene namesi
Name:AVT5
Ordered Locus Names:YBL089W
ORF Names:YBL0703
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBL089w.
SGDiS000000185. AVT5.

Subcellular locationi

Vacuole membrane 1 Publication; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821HelicalSequence AnalysisAdd
BLAST
Transmembranei33 – 5321HelicalSequence AnalysisAdd
BLAST
Transmembranei82 – 10221HelicalSequence AnalysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence AnalysisAdd
BLAST
Transmembranei161 – 18121HelicalSequence AnalysisAdd
BLAST
Transmembranei206 – 22621HelicalSequence AnalysisAdd
BLAST
Transmembranei240 – 26021HelicalSequence AnalysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence AnalysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence AnalysisAdd
BLAST
Transmembranei386 – 40621HelicalSequence AnalysisAdd
BLAST
Transmembranei434 – 45421HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. vacuole Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Vacuolar amino acid transporter 5PRO_0000093838Add
BLAST

Proteomic databases

PRIDEiP38176.

Expressioni

Gene expression databases

GenevestigatoriP38176.

Interactioni

Protein-protein interaction databases

BioGridi32615. 54 interactions.
DIPiDIP-2846N.
IntActiP38176. 2 interactions.
MINTiMINT-505746.
STRINGi4932.YBL089W.

Structurei

3D structure databases

ProteinModelPortaliP38176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0814.
GeneTreeiENSGT00710000106751.
HOGENOMiHOG000173527.
InParanoidiP38176.
OrthoDBiEOG7C8GSX.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38176-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG
60 70 80 90 100
LLLQTRIAKY VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL
110 120 130 140 150
IIVGDLVPQI VQSIFYRNDD NMSGSQEHHM FLDRRLYITL IIVFVISPLC
160 170 180 190 200
FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF VNRHQLERGQ VYFMVPHGDS
210 220 230 240 250
QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI PIFAIVLAYF
260 270 280 290 300
LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC
310 320 330 340 350
HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE
360 370 380 390 400
EPNLRSESLR HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF
410 420 430 440 450
ILPGLFGYKL IGSEFTGTNE RVPTSIKIFK YLSLSLFIWG IAVMVASLSA

IVFLGTSSH
Length:459
Mass (Da):50,892
Last modified:July 11, 2006 - v2
Checksum:i8D3D533A63CD190D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79489 Genomic DNA. Translation: CAA56013.1.
Z35850 Genomic DNA. Translation: CAA84910.1.
BK006936 Genomic DNA. Translation: DAA07035.1.
PIRiS45413.
RefSeqiNP_009464.2. NM_001178329.1.

Genome annotation databases

EnsemblFungiiYBL089W; YBL089W; YBL089W.
GeneIDi852189.
KEGGisce:YBL089W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79489 Genomic DNA. Translation: CAA56013.1 .
Z35850 Genomic DNA. Translation: CAA84910.1 .
BK006936 Genomic DNA. Translation: DAA07035.1 .
PIRi S45413.
RefSeqi NP_009464.2. NM_001178329.1.

3D structure databases

ProteinModelPortali P38176.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32615. 54 interactions.
DIPi DIP-2846N.
IntActi P38176. 2 interactions.
MINTi MINT-505746.
STRINGi 4932.YBL089W.

Protein family/group databases

TCDBi 2.A.18.6.10. the amino acid/auxin permease (aaap) family.

Proteomic databases

PRIDEi P38176.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YBL089W ; YBL089W ; YBL089W .
GeneIDi 852189.
KEGGi sce:YBL089W.

Organism-specific databases

CYGDi YBL089w.
SGDi S000000185. AVT5.

Phylogenomic databases

eggNOGi COG0814.
GeneTreei ENSGT00710000106751.
HOGENOMi HOG000173527.
InParanoidi P38176.
OrthoDBi EOG7C8GSX.

Enzyme and pathway databases

BioCyci YEAST:G3O-28978-MONOMER.

Miscellaneous databases

NextBioi 970664.

Gene expression databases

Genevestigatori P38176.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II."
    Obermaier B., Gassenhuber J., Piravandi E., Domdey H.
    Yeast 11:1103-1112(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "A family of yeast proteins mediating bidirectional vacuolar amino acid transport."
    Russnak R., Konczal D., McIntire S.L.
    J. Biol. Chem. 276:23849-23857(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  5. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
    Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
    Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.

Entry informationi

Entry nameiAVT5_YEAST
AccessioniPrimary (citable) accession number: P38176
Secondary accession number(s): D6VPR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 11, 2006
Last modified: October 29, 2014
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3