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Reviewed, UniProtKB/Swiss-Prot P38176 (AVT5_YEAST)

Last modified November 3, 2009. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Vacuolar amino acid transporter 5
Gene names
Name: AVT5
Ordered Locus Names: YBL089W
ORF Names: YBL0703
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Probable amino acid transporter of unknown specificity. Ref.3

Subcellular location

Vacuole membrane; Multi-pass membrane protein. Ref.3

Sequence similarities

Belongs to the amino acid/polyamine transporter 2 family.

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Ontologies

Keywords
   Biological processAmino-acid transport
Transport
   Cellular componentMembrane
Vacuole
   DomainTransmembrane
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processamino acid transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

vacuole

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 459459Vacuolar amino acid transporter 5
PRO_0000093838

Regions

Transmembrane8 – 2821 Potential
Transmembrane33 – 5321 Potential
Transmembrane82 – 10221 Potential
Transmembrane131 – 15121 Potential
Transmembrane161 – 18121 Potential
Transmembrane206 – 22621 Potential
Transmembrane240 – 26021 Potential
Transmembrane278 – 29821 Potential
Transmembrane364 – 38421 Potential
Transmembrane386 – 40621 Potential
Transmembrane434 – 45421 Potential

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Sequences

Sequence LengthMass (Da)Tools
P38176-1 [UniParc].

Last modified July 11, 2006. Version 2.
Checksum: 8D3D533A63CD190D

FASTA45950,892
        10         20         30         40         50         60 
MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG LLLQTRIAKY 

        70         80         90        100        110        120 
VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL IIVGDLVPQI VQSIFYRNDD 

       130        140        150        160        170        180 
NMSGSQEHHM FLDRRLYITL IIVFVISPLC FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF 

       190        200        210        220        230        240 
VNRHQLERGQ VYFMVPHGDS QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI 

       250        260        270        280        290        300 
PIFAIVLAYF LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC 

       310        320        330        340        350        360 
HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE EPNLRSESLR 

       370        380        390        400        410        420 
HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF ILPGLFGYKL IGSEFTGTNE 

       430        440        450 
RVPTSIKIFK YLSLSLFIWG IAVMVASLSA IVFLGTSSH

« Hide

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References

« Hide 'large scale' references
[1]"Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II."
Obermaier B., Gassenhuber J., Piravandi E., Domdey H.
Yeast 11:1103-1112(1995) [PubMed: 7502586] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome II."
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. expand/collapse author list , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"A family of yeast proteins mediating bidirectional vacuolar amino acid transport."
Russnak R., Konczal D., McIntire S.L.
J. Biol. Chem. 276:23849-23857(2001) [PubMed: 11274162] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
[4]"Sequencing and comparison of yeast species to identify genes and regulatory elements."
Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
Nature 423:241-254(2003) [PubMed: 12748633] [Abstract]
Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

X79489 Genomic DNA. Translation: CAA56013.1.
Z35850 Genomic DNA. Translation: CAA84910.1.
PIRS45413.
RefSeqNP_009464.2.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:2846N.
IntActP38176. 4 interactions.
STRINGP38176.

Genome annotation databases

EnsemblYBL089W; YBL089W; YBL089W; Saccharomyces cerevisiae. [Genome view]
GeneID852189.
GenomeReviewsGene locus YBL089W in contig Y13134_GR.
KEGGsce:YBL089W.
NMPDRfig|4932.3.peg.150.

Organism-specific databases

CYGDYBL089w.
SGDS000000185. AVT5.

Phylogenomic databases

HOGENOMP38176.
OMAHINIITL.

Gene expression databases

ArrayExpressP38176.
GenevestigatorP38176.
GermOnlineYBL089W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR013057. AA_transpt_TM.
[Graphical view]
PfamPF01490. Aa_trans. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio970664.

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Entry information

Entry nameAVT5_YEAST
AccessionPrimary (citable) accession number: P38176
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 11, 2006
Last modified: November 3, 2009
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome II

Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents