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P38176

- AVT5_YEAST

UniProt

P38176 - AVT5_YEAST

Protein

Vacuolar amino acid transporter 5

Gene

AVT5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 2 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    Probable amino acid transporter of unknown specificity.1 Publication

    GO - Molecular functioni

    1. transporter activity Source: SGD

    GO - Biological processi

    1. amino acid transport Source: UniProtKB-KW
    2. transport Source: SGD

    Keywords - Biological processi

    Amino-acid transport, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-28978-MONOMER.

    Protein family/group databases

    TCDBi2.A.18.6.10. the amino acid/auxin permease (aaap) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Vacuolar amino acid transporter 5
    Gene namesi
    Name:AVT5
    Ordered Locus Names:YBL089W
    ORF Names:YBL0703
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome II

    Organism-specific databases

    CYGDiYBL089w.
    SGDiS000000185. AVT5.

    Subcellular locationi

    Vacuole membrane 1 Publication; Multi-pass membrane protein 1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. vacuolar membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Vacuole

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 459459Vacuolar amino acid transporter 5PRO_0000093838Add
    BLAST

    Proteomic databases

    PRIDEiP38176.

    Expressioni

    Gene expression databases

    GenevestigatoriP38176.

    Interactioni

    Protein-protein interaction databases

    BioGridi32615. 54 interactions.
    DIPiDIP-2846N.
    IntActiP38176. 2 interactions.
    MINTiMINT-505746.
    STRINGi4932.YBL089W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38176.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei33 – 5321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei82 – 10221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei131 – 15121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei161 – 18121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei206 – 22621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei240 – 26021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei278 – 29821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei364 – 38421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei386 – 40621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei434 – 45421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0814.
    GeneTreeiENSGT00710000106751.
    HOGENOMiHOG000173527.
    OrthoDBiEOG7C8GSX.

    Family and domain databases

    InterProiIPR013057. AA_transpt_TM.
    [Graphical view]
    PfamiPF01490. Aa_trans. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P38176-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG    50
    LLLQTRIAKY VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL 100
    IIVGDLVPQI VQSIFYRNDD NMSGSQEHHM FLDRRLYITL IIVFVISPLC 150
    FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF VNRHQLERGQ VYFMVPHGDS 200
    QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI PIFAIVLAYF 250
    LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC 300
    HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE 350
    EPNLRSESLR HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF 400
    ILPGLFGYKL IGSEFTGTNE RVPTSIKIFK YLSLSLFIWG IAVMVASLSA 450
    IVFLGTSSH 459
    Length:459
    Mass (Da):50,892
    Last modified:July 11, 2006 - v2
    Checksum:i8D3D533A63CD190D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X79489 Genomic DNA. Translation: CAA56013.1.
    Z35850 Genomic DNA. Translation: CAA84910.1.
    BK006936 Genomic DNA. Translation: DAA07035.1.
    PIRiS45413.
    RefSeqiNP_009464.2. NM_001178329.1.

    Genome annotation databases

    EnsemblFungiiYBL089W; YBL089W; YBL089W.
    GeneIDi852189.
    KEGGisce:YBL089W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X79489 Genomic DNA. Translation: CAA56013.1 .
    Z35850 Genomic DNA. Translation: CAA84910.1 .
    BK006936 Genomic DNA. Translation: DAA07035.1 .
    PIRi S45413.
    RefSeqi NP_009464.2. NM_001178329.1.

    3D structure databases

    ProteinModelPortali P38176.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 32615. 54 interactions.
    DIPi DIP-2846N.
    IntActi P38176. 2 interactions.
    MINTi MINT-505746.
    STRINGi 4932.YBL089W.

    Protein family/group databases

    TCDBi 2.A.18.6.10. the amino acid/auxin permease (aaap) family.

    Proteomic databases

    PRIDEi P38176.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YBL089W ; YBL089W ; YBL089W .
    GeneIDi 852189.
    KEGGi sce:YBL089W.

    Organism-specific databases

    CYGDi YBL089w.
    SGDi S000000185. AVT5.

    Phylogenomic databases

    eggNOGi COG0814.
    GeneTreei ENSGT00710000106751.
    HOGENOMi HOG000173527.
    OrthoDBi EOG7C8GSX.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-28978-MONOMER.

    Miscellaneous databases

    NextBioi 970664.

    Gene expression databases

    Genevestigatori P38176.

    Family and domain databases

    InterProi IPR013057. AA_transpt_TM.
    [Graphical view ]
    Pfami PF01490. Aa_trans. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II."
      Obermaier B., Gassenhuber J., Piravandi E., Domdey H.
      Yeast 11:1103-1112(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete DNA sequence of yeast chromosome II."
      Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
      , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
      EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "A family of yeast proteins mediating bidirectional vacuolar amino acid transport."
      Russnak R., Konczal D., McIntire S.L.
      J. Biol. Chem. 276:23849-23857(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.
    5. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
      Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
      Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.

    Entry informationi

    Entry nameiAVT5_YEAST
    AccessioniPrimary (citable) accession number: P38176
    Secondary accession number(s): D6VPR5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 93 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome II
      Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

    External Data

    Dasty 3