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P38176

- AVT5_YEAST

UniProt

P38176 - AVT5_YEAST

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Protein
Vacuolar amino acid transporter 5
Gene
AVT5, YBL089W, YBL0703
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Probable amino acid transporter of unknown specificity.1 Publication

GO - Molecular functioni

  1. transporter activity Source: SGD
Complete GO annotation...

GO - Biological processi

  1. amino acid transport Source: UniProtKB-KW
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-28978-MONOMER.

Protein family/group databases

TCDBi2.A.18.6.10. the amino acid/auxin permease (aaap) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar amino acid transporter 5
Gene namesi
Name:AVT5
Ordered Locus Names:YBL089W
ORF Names:YBL0703
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBL089w.
SGDiS000000185. AVT5.

Subcellular locationi

Vacuole membrane; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821Helical; Reviewed prediction
Add
BLAST
Transmembranei33 – 5321Helical; Reviewed prediction
Add
BLAST
Transmembranei82 – 10221Helical; Reviewed prediction
Add
BLAST
Transmembranei131 – 15121Helical; Reviewed prediction
Add
BLAST
Transmembranei161 – 18121Helical; Reviewed prediction
Add
BLAST
Transmembranei206 – 22621Helical; Reviewed prediction
Add
BLAST
Transmembranei240 – 26021Helical; Reviewed prediction
Add
BLAST
Transmembranei278 – 29821Helical; Reviewed prediction
Add
BLAST
Transmembranei364 – 38421Helical; Reviewed prediction
Add
BLAST
Transmembranei386 – 40621Helical; Reviewed prediction
Add
BLAST
Transmembranei434 – 45421Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. vacuolar membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Vacuolar amino acid transporter 5
PRO_0000093838Add
BLAST

Proteomic databases

PRIDEiP38176.

Expressioni

Gene expression databases

GenevestigatoriP38176.

Interactioni

Protein-protein interaction databases

BioGridi32615. 54 interactions.
DIPiDIP-2846N.
IntActiP38176. 2 interactions.
MINTiMINT-505746.
STRINGi4932.YBL089W.

Structurei

3D structure databases

ProteinModelPortaliP38176.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0814.
GeneTreeiENSGT00710000106751.
HOGENOMiHOG000173527.
OrthoDBiEOG7C8GSX.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38176-1 [UniParc]FASTAAdd to Basket

« Hide

MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG    50
LLLQTRIAKY VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL 100
IIVGDLVPQI VQSIFYRNDD NMSGSQEHHM FLDRRLYITL IIVFVISPLC 150
FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF VNRHQLERGQ VYFMVPHGDS 200
QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI PIFAIVLAYF 250
LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC 300
HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE 350
EPNLRSESLR HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF 400
ILPGLFGYKL IGSEFTGTNE RVPTSIKIFK YLSLSLFIWG IAVMVASLSA 450
IVFLGTSSH 459
Length:459
Mass (Da):50,892
Last modified:July 11, 2006 - v2
Checksum:i8D3D533A63CD190D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79489 Genomic DNA. Translation: CAA56013.1.
Z35850 Genomic DNA. Translation: CAA84910.1.
BK006936 Genomic DNA. Translation: DAA07035.1.
PIRiS45413.
RefSeqiNP_009464.2. NM_001178329.1.

Genome annotation databases

EnsemblFungiiYBL089W; YBL089W; YBL089W.
GeneIDi852189.
KEGGisce:YBL089W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79489 Genomic DNA. Translation: CAA56013.1 .
Z35850 Genomic DNA. Translation: CAA84910.1 .
BK006936 Genomic DNA. Translation: DAA07035.1 .
PIRi S45413.
RefSeqi NP_009464.2. NM_001178329.1.

3D structure databases

ProteinModelPortali P38176.
ModBasei Search...

Protein-protein interaction databases

BioGridi 32615. 54 interactions.
DIPi DIP-2846N.
IntActi P38176. 2 interactions.
MINTi MINT-505746.
STRINGi 4932.YBL089W.

Protein family/group databases

TCDBi 2.A.18.6.10. the amino acid/auxin permease (aaap) family.

Proteomic databases

PRIDEi P38176.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YBL089W ; YBL089W ; YBL089W .
GeneIDi 852189.
KEGGi sce:YBL089W.

Organism-specific databases

CYGDi YBL089w.
SGDi S000000185. AVT5.

Phylogenomic databases

eggNOGi COG0814.
GeneTreei ENSGT00710000106751.
HOGENOMi HOG000173527.
OrthoDBi EOG7C8GSX.

Enzyme and pathway databases

BioCyci YEAST:G3O-28978-MONOMER.

Miscellaneous databases

NextBioi 970664.

Gene expression databases

Genevestigatori P38176.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II."
    Obermaier B., Gassenhuber J., Piravandi E., Domdey H.
    Yeast 11:1103-1112(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "A family of yeast proteins mediating bidirectional vacuolar amino acid transport."
    Russnak R., Konczal D., McIntire S.L.
    J. Biol. Chem. 276:23849-23857(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  5. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
    Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
    Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.

Entry informationi

Entry nameiAVT5_YEAST
AccessioniPrimary (citable) accession number: P38176
Secondary accession number(s): D6VPR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 11, 2006
Last modified: May 14, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

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