Reviewed, UniProtKB/Swiss-Prot P38163 (SNI2_YEAST)

Names and origin

Protein names

Recommended name:
    Protein SNI2
Alternative name(s):
    Suppressor of RHO3 protein 77

Gene names

Name:	SNI2
Synonyms:	SRO77
Ordered Locus Names:	YBL106C
ORF Names:	YBL0806

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	1010 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May be involved in the targeting of the myosin proteins to their intrinsic pathways.
Sequence similarities	Belongs to the WD repeat L(2)GL family. Contains 14 WD repeats.

Ontologies

Keywords
Biological process	Exocytosis
Domain	Repeat WD repeat
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	Golgi to plasma membrane transport Inferred from genetic interaction. Source: SGD exocytosis Inferred from genetic interaction. Source: SGD
Cellular component	plasma membrane Inferred from physical interaction. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1010	1010	Protein SNI2		PRO_0000051221
Regions
	Repeat	47 – 80	34	WD 1
	Repeat	87 – 122	36	WD 2
	Repeat	127 – 163	37	WD 3
	Repeat	182 – 215	34	WD 4
	Repeat	240 – 275	36	WD 5
	Repeat	299 – 364	66	WD 6
	Repeat	372 – 407	36	WD 7
	Repeat	431 – 504	74	WD 8
	Repeat	518 – 595	78	WD 9
	Repeat	602 – 637	36	WD 10
	Repeat	649 – 700	52	WD 11
	Repeat	709 – 763	55	WD 12
	Repeat	768 – 815	48	WD 13
	Repeat	829 – 852	24	WD 14
Amino acid modifications
	Modified residue	744	1	Phosphoserine Ref.4

Sequences

	Sequence		Length	Mass (Da)
	P38163-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 898BC9174CC12606	FASTA	1,010	111,678
	10 20 30 40 50 60 MFKKSRHLKN VSNAIKSARV HDVSNGINSK FFDTKKICTY GINGRITVTT FDYTQSLLAV 70 80 90 100 110 120 ATTAGEIHVY GQKQIEVVFT LKNRPQIKHM RFIKGIYLIA VDEKSNIIVL SVHSKQILTT 130 140 150 160 170 180 VFCPNSITCF ETDPPLDWML IGLESGSILI YDVDRNQMSK LKIENFQKSV FLPKERLSPV 190 200 210 220 230 240 ISIQWNPRDI GTILISYEHI TVIYSFIDYK VKQHFFYQLE PYAPGGDLST NIEKKRTPKV 250 260 270 280 290 300 IQSLYHPNSL HILTVHEDNA LVFWDVNSGK LIHARSIFET HVNFPNPALK DCSFTETPAI 310 320 330 340 350 360 FKVSWLCQRN PEYTSLLIAT KATENPCLPQ EITMIDLGGT PMYSVTSFDA MSKYYAKPVQ 370 380 390 400 410 420 QKLFSLIGKA PLINFLPLPK ASPYFGGCHD TNLILLLLED GELETLIYPA GSFSSKASIF 430 440 450 460 470 480 PRSLAWVRPT VTTCIAQSVQ KNLWLGMMTI AQSESFLKGG IPATRNIRRH ETRSALLTGH 490 500 510 520 530 540 SNGSVRIWDA SHSEVTDNAV FEVNTAKVLN RATNLAIKNI SFASETLELA VSSEVGDVIL 550 560 570 580 590 600 FKFETNKFYG QLPKSDALQL KFSRFSLDDS KTILVDVSDR GPTNVKQGFI PSTVIHAKKG 610 620 630 640 650 660 AVSAIMNSNI GFVAVGFIEG TLIILDRRGP AIIFNENIRV ISKAGSSYVS TVHFCVMEYG 670 680 690 700 710 720 DDGFSSILML CGTDIGELMT FKILPATNGR FEVKFTDATK TNNQGKILGI NSFAKDTGYS 730 740 750 760 770 780 CSATISKMQG LSKGIAIPGF VTISGANDIR LVSPGKSKDT HALFKYPIAT SGLSFIPIID 790 800 810 820 830 840 GKGERKLSTI MIVLLINGDI KVLTVPELKE VKNLRCPVPL SAQYVENSSI LENVDIVIRT 850 860 870 880 890 900 GKFQASLISV LNESATGSNH TADISQHTPI DTLYNPDLKI GYRPQVNSLQ WARGTIYCTP 910 920 930 940 950 960 YQLDELLGGI ERPESKYEES AIARGCISSS SSNAARKLPP GTKDHRYARP VRSSGRSNGY 970 980 990 1000 1010 GVLKSVSRAI ETRLDTVETT INDYATTMGQ TMNDAMEETG RDMMKSAVGF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II." Obermaier B., Gassenhuber J., Piravandi E., Domdey H. Yeast 11:1103-1112(1995) [PubMed: 7502586] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Sro7p, a Saccharomyces cerevisiae counterpart of the tumor suppressor l(2)gl protein, is related to myosins in function." Kagami M., Toh-e A., Matsui Y. Genetics 149:1717-1727(1998) [PubMed: 9691031] [Abstract] Cited for: CHARACTERIZATION.
[4]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-744, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X79489 Genomic DNA. Translation: CAA55989.1. Z35867 Genomic DNA. Translation: CAA84933.1.
PIR	S45389.
RefSeq	NP_009444.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:2947N.
IntAct	P38163. 10 interactions.
STRING	P38163.
Genome annotation databases
Ensembl	YBL106C; YBL106C; YBL106C; Saccharomyces cerevisiae. [Genome view]
GeneID	852168.
GenomeReviews	Gene locus YBL106C in contig Y13134_GR.
KEGG	sce:YBL106C.
NMPDR	fig|4932.3.peg.129.
Organism-specific databases
CYGD	YBL106c.
SGD	S000000202. SRO77.
Phylogenomic databases
HOGENOM	P38163.
OMA	AYDPVQS.
Gene expression databases
ArrayExpress	P38163.
Genevestigator	P38163.
GermOnline	YBL106C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR013905. Lgl_C. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019782. WD40_repeat_2. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF08596. Lgl_C. 1 hit. [Graphical view]
SMART	SM00320. WD40. 5 hits. [Graphical view]
PROSITE	PS00678. WD_REPEATS_1. 2 hits. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	970611.

Entry information

Entry name

SNI2_YEAST

Accession

Primary (citable) accession number: P38163

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	November 3, 2009
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)