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UniProtKB - P38156 (MAL31_YEAST)

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Protein

Maltose permease MAL31

Gene

MAL31

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

High-affinity uptake of maltose and maltotriose. Also transports turanose but not alpha-methylglucoside, melezitose or trehalose.1 Publication

GO - Molecular functioni

Complete GO annotation...

GO - Biological processi

  • alpha-glucoside transport Source: SGD
  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • maltose metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywordsi

Biological processMaltose metabolism, Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29216-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Maltose permease MAL31
Alternative name(s):
Maltose transport protein MAL31
Gene namesi
Name:MAL31
Synonyms:MAL3T
Ordered Locus Names:YBR298C
ORF Names:YBR2116
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR298C.
SGDiS000000502. MAL31.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 108CytoplasmicSequence analysisAdd BLAST108
Transmembranei109 – 129Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini130 – 144ExtracellularSequence analysisAdd BLAST15
Transmembranei145 – 165Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini166 – 180CytoplasmicSequence analysisAdd BLAST15
Transmembranei181 – 201Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini202ExtracellularSequence analysis1
Transmembranei203 – 223Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini224 – 236CytoplasmicSequence analysisAdd BLAST13
Transmembranei237 – 257Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini258 – 272ExtracellularSequence analysisAdd BLAST15
Transmembranei273 – 293Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini294 – 364CytoplasmicSequence analysisAdd BLAST71
Transmembranei365 – 385Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini386 – 398ExtracellularSequence analysisAdd BLAST13
Transmembranei399 – 419Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini420 – 427CytoplasmicSequence analysis8
Transmembranei428 – 448Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini449 – 460ExtracellularSequence analysisAdd BLAST12
Transmembranei461 – 481Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini482 – 493CytoplasmicSequence analysisAdd BLAST12
Transmembranei494 – 514Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini515 – 526ExtracellularSequence analysisAdd BLAST12
Transmembranei527 – 547Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini548 – 614CytoplasmicSequence analysisAdd BLAST67

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504221 – 614Maltose permease MAL31Add BLAST614

Proteomic databases

PRIDEiP38156.

Expressioni

Inductioni

By maltose and maltotriose. Repressed by glucose.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi32991. 82 interactors.
DIPiDIP-7544N.
IntActiP38156. 16 interactors.
MINTiMINT-1355724.

Structurei

3D structure databases

ProteinModelPortaliP38156.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00880000138680.
HOGENOMiHOG000159003.
InParanoidiP38156.
KOiK08141.
OMAiMTYFGRR.
OrthoDBiEOG092C1DHG.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
PfamiView protein in Pfam
PF00083. Sugar_tr. 1 hit.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiView protein in PROSITE
PS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P38156-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLSSLINR KKDRNDSHLD EIENGVNATE FNSIEMEEQG KKSDFDLSHL 
        60         70         80         90        100
EYGPGSLIPN DNNEEVPDLL DEAMQDAKEA DESERGMPLM TALKTYPKAA 
       110        120        130        140        150
AWSLLVSTTL IQEGYDTAIL GAFYALPVFQ KKYGSLNSNT GDYEISVSWQ 
       160        170        180        190        200
IGLCLCYMAG EIVGLQMTGP SVDYMGNRYT LIMALFFLAA FIFILYFCKS 
       210        220        230        240        250
LGMIAVGQAL CGMPWGCFQC LTVSYASEIC PLALRYYLTT YSNLCWAFGQ 
       260        270        280        290        300
LFAAGIMKNS QNKYANSELG YKLPFALQWI WPLPLAVGIF FAPESPWWLV 
       310        320        330        340        350
KKGRIDQARR SLERTLSGKG PEKELLVSME LDKIKTTIEK EQKMSDEGTY 
       360        370        380        390        400
WDCVKDGINR RRTRIACLCW IGQCSCGASL IGYSTYFYEK AGVSTDTAFT 
       410        420        430        440        450
FSIIQYCLGI AATFISWWAS KYCGRFDLYA FGLAFQAIMF FIIGGLGCSD 
       460        470        480        490        500
THGAKMGSGA LLMVVAFFYN LGIAPVVFCL VSEIPSSRLR TKTIILARNA 
       510        520        530        540        550
YNVIQVVVTV LIMYQLNSEK WNWGAKSGFF WGGFCLATLA WAVVDLPETA 
       560        570        580        590        600
GRTFIEINEL FRLGVPARKF KSTKVDPFAA AKAAAAEINV KDPKEDLETS 
       610 
VVDEGRNTSS VVNK
Length:614
Mass (Da):68,263
Last modified:October 1, 1994 - v1
Checksum:i897FD1DE9AC995CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ010169 Genomic DNA. Translation: AAY67702.1.
Z36167 Genomic DNA. Translation: CAA85263.1.
AY692794 Genomic DNA. Translation: AAT92813.1.
BK006936 Genomic DNA. Translation: DAA07413.1.
PIRiS46182.
RefSeqiNP_009857.1. NM_001178646.1.

Genome annotation databases

EnsemblFungiiYBR298C; YBR298C; YBR298C.
GeneIDi852601.
KEGGisce:YBR298C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ010169 Genomic DNA. Translation: AAY67702.1.
Z36167 Genomic DNA. Translation: CAA85263.1.
AY692794 Genomic DNA. Translation: AAT92813.1.
BK006936 Genomic DNA. Translation: DAA07413.1.
PIRiS46182.
RefSeqiNP_009857.1. NM_001178646.1.

3D structure databases

ProteinModelPortaliP38156.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32991. 82 interactors.
DIPiDIP-7544N.
IntActiP38156. 16 interactors.
MINTiMINT-1355724.

Proteomic databases

PRIDEiP38156.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR298C; YBR298C; YBR298C.
GeneIDi852601.
KEGGisce:YBR298C.

Organism-specific databases

EuPathDBiFungiDB:YBR298C.
SGDiS000000502. MAL31.

Phylogenomic databases

GeneTreeiENSGT00880000138680.
HOGENOMiHOG000159003.
InParanoidiP38156.
KOiK08141.
OMAiMTYFGRR.
OrthoDBiEOG092C1DHG.

Enzyme and pathway databases

BioCyciYEAST:G3O-29216-MONOMER.

Miscellaneous databases

PROiPR:P38156.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
PfamiView protein in Pfam
PF00083. Sugar_tr. 1 hit.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiView protein in PROSITE
PS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMAL31_YEAST
AccessioniPrimary (citable) accession number: P38156
Secondary accession number(s): D6VQU3, Q3SCJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: June 7, 2017
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.