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Protein

Maltose permease MAL31

Gene

MAL31

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

High-affinity uptake of maltose and maltotriose. Also transports turanose but not alpha-methylglucoside, melezitose or trehalose.1 Publication

GO - Molecular functioni

GO - Biological processi

  • alpha-glucoside transport Source: SGD
  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • maltose metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Maltose metabolism, Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29216-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Maltose permease MAL31
Alternative name(s):
Maltose transport protein MAL31
Gene namesi
Name:MAL31
Synonyms:MAL3T
Ordered Locus Names:YBR298C
ORF Names:YBR2116
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR298C.
SGDiS000000502. MAL31.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 108108CytoplasmicSequence analysisAdd
BLAST
Transmembranei109 – 12921Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini130 – 14415ExtracellularSequence analysisAdd
BLAST
Transmembranei145 – 16521Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini166 – 18015CytoplasmicSequence analysisAdd
BLAST
Transmembranei181 – 20121Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini202 – 2021ExtracellularSequence analysis
Transmembranei203 – 22321Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini224 – 23613CytoplasmicSequence analysisAdd
BLAST
Transmembranei237 – 25721Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini258 – 27215ExtracellularSequence analysisAdd
BLAST
Transmembranei273 – 29321Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini294 – 36471CytoplasmicSequence analysisAdd
BLAST
Transmembranei365 – 38521Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini386 – 39813ExtracellularSequence analysisAdd
BLAST
Transmembranei399 – 41921Helical; Name=8Sequence analysisAdd
BLAST
Topological domaini420 – 4278CytoplasmicSequence analysis
Transmembranei428 – 44821Helical; Name=9Sequence analysisAdd
BLAST
Topological domaini449 – 46012ExtracellularSequence analysisAdd
BLAST
Transmembranei461 – 48121Helical; Name=10Sequence analysisAdd
BLAST
Topological domaini482 – 49312CytoplasmicSequence analysisAdd
BLAST
Transmembranei494 – 51421Helical; Name=11Sequence analysisAdd
BLAST
Topological domaini515 – 52612ExtracellularSequence analysisAdd
BLAST
Transmembranei527 – 54721Helical; Name=12Sequence analysisAdd
BLAST
Topological domaini548 – 61467CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 614614Maltose permease MAL31PRO_0000050422Add
BLAST

Expressioni

Inductioni

By maltose and maltotriose. Repressed by glucose.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi32991. 45 interactions.
DIPiDIP-7544N.
IntActiP38156. 16 interactions.
MINTiMINT-1355724.

Structurei

3D structure databases

ProteinModelPortaliP38156.
SMRiP38156. Positions 111-561.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00720000109429.
HOGENOMiHOG000159003.
InParanoidiP38156.
KOiK08141.
OMAiDQFAGHE.
OrthoDBiEOG092C1DHG.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38156-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLSSLINR KKDRNDSHLD EIENGVNATE FNSIEMEEQG KKSDFDLSHL
60 70 80 90 100
EYGPGSLIPN DNNEEVPDLL DEAMQDAKEA DESERGMPLM TALKTYPKAA
110 120 130 140 150
AWSLLVSTTL IQEGYDTAIL GAFYALPVFQ KKYGSLNSNT GDYEISVSWQ
160 170 180 190 200
IGLCLCYMAG EIVGLQMTGP SVDYMGNRYT LIMALFFLAA FIFILYFCKS
210 220 230 240 250
LGMIAVGQAL CGMPWGCFQC LTVSYASEIC PLALRYYLTT YSNLCWAFGQ
260 270 280 290 300
LFAAGIMKNS QNKYANSELG YKLPFALQWI WPLPLAVGIF FAPESPWWLV
310 320 330 340 350
KKGRIDQARR SLERTLSGKG PEKELLVSME LDKIKTTIEK EQKMSDEGTY
360 370 380 390 400
WDCVKDGINR RRTRIACLCW IGQCSCGASL IGYSTYFYEK AGVSTDTAFT
410 420 430 440 450
FSIIQYCLGI AATFISWWAS KYCGRFDLYA FGLAFQAIMF FIIGGLGCSD
460 470 480 490 500
THGAKMGSGA LLMVVAFFYN LGIAPVVFCL VSEIPSSRLR TKTIILARNA
510 520 530 540 550
YNVIQVVVTV LIMYQLNSEK WNWGAKSGFF WGGFCLATLA WAVVDLPETA
560 570 580 590 600
GRTFIEINEL FRLGVPARKF KSTKVDPFAA AKAAAAEINV KDPKEDLETS
610
VVDEGRNTSS VVNK
Length:614
Mass (Da):68,263
Last modified:October 1, 1994 - v1
Checksum:i897FD1DE9AC995CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ010169 Genomic DNA. Translation: AAY67702.1.
Z36167 Genomic DNA. Translation: CAA85263.1.
AY692794 Genomic DNA. Translation: AAT92813.1.
BK006936 Genomic DNA. Translation: DAA07413.1.
PIRiS46182.
RefSeqiNP_009857.1. NM_001178646.1.

Genome annotation databases

EnsemblFungiiYBR298C; YBR298C; YBR298C.
GeneIDi852601.
KEGGisce:YBR298C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ010169 Genomic DNA. Translation: AAY67702.1.
Z36167 Genomic DNA. Translation: CAA85263.1.
AY692794 Genomic DNA. Translation: AAT92813.1.
BK006936 Genomic DNA. Translation: DAA07413.1.
PIRiS46182.
RefSeqiNP_009857.1. NM_001178646.1.

3D structure databases

ProteinModelPortaliP38156.
SMRiP38156. Positions 111-561.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32991. 45 interactions.
DIPiDIP-7544N.
IntActiP38156. 16 interactions.
MINTiMINT-1355724.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR298C; YBR298C; YBR298C.
GeneIDi852601.
KEGGisce:YBR298C.

Organism-specific databases

EuPathDBiFungiDB:YBR298C.
SGDiS000000502. MAL31.

Phylogenomic databases

GeneTreeiENSGT00720000109429.
HOGENOMiHOG000159003.
InParanoidiP38156.
KOiK08141.
OMAiDQFAGHE.
OrthoDBiEOG092C1DHG.

Enzyme and pathway databases

BioCyciYEAST:G3O-29216-MONOMER.

Miscellaneous databases

PROiP38156.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMAL31_YEAST
AccessioniPrimary (citable) accession number: P38156
Secondary accession number(s): D6VQU3, Q3SCJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: September 7, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.