Reviewed, UniProtKB/Swiss-Prot P38150 (YB9Z_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized deaminase YBR284W
    EC=3.5.4.-

Gene names

Ordered Locus Names:	YBR284W
ORF Names:	YBR2021

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	797 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine base metabolic process Inferred from electronic annotation. Source: InterPro purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	deaminase activity Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
GUD1	Q07729	1	EBI-21180,EBI-7985

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 797	797	Uncharacterized deaminase YBR284W		PRO_0000194415
Regions
	Transmembrane	627 – 647	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P38150-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: BF854E93D0B2C747	FASTA	797	92,904
	10 20 30 40 50 60 MVQNNESVFF VECDSYKESP STSPIRLDDL DGNDAVSDQG LAFDGDVGIT SQARVRNPRA 70 80 90 100 110 120 QIFEDSNTDV VLHLDDLDMV PLNTKFDMQM EMGSPMAMPA ETPPPVEPLK TKDLAYSSLA 130 140 150 160 170 180 HLPSYFFEQT HFRIDRKCLL EMSKLRRNYL TISKQDALSC PQLHSRVAGG YLKPVKEKLF 190 200 210 220 230 240 GIRHFLDLEE SNTVNLLQDG NYMTELFNSQ INIPTFKEFR EDFEWCLKII RDRSLSRFSE 250 260 270 280 290 300 KRLQYLVNKF PVFQHLHSKE EMRQSKKVPH KDFYNCRKID LNLLLSGCFS QWQLTEFIWT 310 320 330 340 350 360 KLRKEPDRVI HQAFNGSHIT LSQLFKVNFE ETGQFFNGLK IIDDSFLEWY KVIYLAKYHL 370 380 390 400 410 420 VNDEMEIHTG SHGKQLRYYL IAKTFLEFDN YINGEYLAEL LKTFLIKPQE ESKYQLCQLS 430 440 450 460 470 480 VDFQFYLHYD NSDVDNWWMV FANWLNHYNI FSNNIRWNIR ISRIYPELYH TGKVKNFQEY 490 500 510 520 530 540 LNLIFKPLFN AENYLHKSLG PILLKFLSQV SSIDLCIQDT DNYIWKNFTA VSCLPKDWTS 550 560 570 580 590 600 GGDNPTISQY MYYVYVNLTK LNHIRQALHQ NTFTLRSSCS PTSMNRTSQF SNTLNFTEHT 610 620 630 640 650 660 EAILNNFLLA CGGFLNAENL WNAPPSLVYL FYLSQIPMVV APLNSIVDSK PTMLQEQAPT 670 680 690 700 710 720 GLVLEPSKPY KKNPFMKFFE MGFKISLSSE SILYNNSYTK EPIIEEYSVA ASIYRLHSAD 730 740 750 760 770 780 LCELLRNSVI TSGFSSTLKN KWLGVSLASH DYFVENTGFV DKWYDCKPNT SLEHNVPIIR 790 RQYRSSTLAG EWRLIIA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of a 32,420 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae." Holmstroem K., Brandt T., Kallesoe T. Yeast 10:S47-S62(1994) [PubMed: 8091861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X76053 Genomic DNA. Translation: CAA53647.1. Z36153 Genomic DNA. Translation: CAA85248.1.
PIR	S44546.
RefSeq	NP_009843.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1257N.
IntAct	P38150. 4 interactions.
Genome annotation databases
Ensembl	YBR284W. Saccharomyces cerevisiae. [Contig view]
GeneID	852587.
GenomeReviews	Gene locus YBR284W in contig Y13134_GR.
KEGG	sce:YBR284W.
NMPDR	fig|4932.3.peg.559.
Organism-specific databases
CYGD	YBR284w.
SGD	S000000488. YBR284W.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P38150.
OMA	P38150. CEINDIS.
Gene expression databases
ArrayExpress	P38150.
GermOnline	YBR284W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001365. A/AMP_deaminase. IPR016297. AMP_deaminase_met. [Graphical view]
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
PIRSF	PIRSF001251. AMP_deaminase_met. 1 hit.
ProtoNet	Search...
Other Resources
NextBio	971742.

Entry information

Entry name

YB9Z_YEAST

Accession

Primary (citable) accession number: P38150

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)