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P38127 (RIM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 111. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitochondrial carrier protein RIM2
Gene names
Name:RIM2
Ordered Locus Names:YBR192W
ORF Names:YBR1402
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]

Contains 3 Solcar repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 377377Mitochondrial carrier protein RIM2
PRO_0000090690

Regions

Transmembrane53 – 7321Helical; Name=1; Potential
Transmembrane131 – 15121Helical; Name=2; Potential
Transmembrane179 – 19921Helical; Name=3; Potential
Transmembrane238 – 25821Helical; Name=4; Potential
Transmembrane286 – 30621Helical; Name=5; Potential
Transmembrane347 – 36822Helical; Name=6; Potential
Repeat50 – 163114Solcar 1
Repeat173 – 26290Solcar 2
Repeat286 – 37590Solcar 3

Sequences

Sequence LengthMass (Da)Tools
P38127 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: A3C61383C3B3743B

FASTA37742,102
        10         20         30         40         50         60 
MPKKSIEEWE EDAIESVPYL ASDEKGSNYK EATQIPLNLK QSEIENHPTV KPWVHFVAGG 

        70         80         90        100        110        120 
IGGMAGAVVT CPFDLVKTRL QSDIFLKAYK SQAVNISKGS TRPKSINYVI QAGTHFKETL 

       130        140        150        160        170        180 
GIIGNVYKQE GFRSLFKGLG PNLVGVIPAR SINFFTYGTT KDMYAKAFNN GQETPMIHLM 

       190        200        210        220        230        240 
AAATAGWATA TATNPIWLIK TRVQLDKAGK TSVRQYKNSW DCLKSVIRNE GFTGLYKGLS 

       250        260        270        280        290        300 
ASYLGSVEGI LQWLLYEQMK RLIKERSIEK FGYQAEGTKS TSEKVKEWCQ RSGSAGLAKF 

       310        320        330        340        350        360 
VASIATYPHE VVRTRLRQTP KENGKRKYTG LVQSFKVIIK EEGLFSMYSG LTPHLMRTVP 

       370 
NSIIMFGTWE IVIRLLS 

« Hide

References

« Hide 'large scale' references
[1]"RIM2, MSI1 and PGI1 are located within an 8 kb segment of Saccharomyces cerevisiae chromosome II, which also contains the putative ribosomal gene L21 and a new putative essential gene with a leucine zipper motif."
Demolis N., Mallet L., Bussereau F., Jacquet M.
Yeast 9:645-659(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome II."
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. expand/collapse author list , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z21487 Genomic DNA. Translation: CAA79678.1.
Z36061 Genomic DNA. Translation: CAA85154.1.
AY557871 Genomic DNA. Translation: AAS56197.1.
BK006936 Genomic DNA. Translation: DAA07306.1.
PIRS36081.
RefSeqNP_009751.1. NM_001178540.1.

3D structure databases

ProteinModelPortalP38127.
SMRP38127. Positions 53-376.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid32889. 16 interactions.
DIPDIP-4933N.
MINTMINT-507683.
STRING4932.YBR192W.

Protein family/group databases

TCDB2.A.29.10.4. the mitochondrial carrier (mc) family.

Proteomic databases

PaxDbP38127.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYBR192W; YBR192W; YBR192W.
GeneID852491.
KEGGsce:YBR192W.

Organism-specific databases

CYGDYBR192w.
SGDS000000396. RIM2.

Phylogenomic databases

eggNOGNOG301650.
GeneTreeENSGT00550000074670.
HOGENOMHOG000188210.
KOK15116.
OMAQIMAISH.
OrthoDBEOG7N905P.

Enzyme and pathway databases

BioCycYEAST:G3O-29134-MONOMER.

Gene expression databases

GenevestigatorP38127.

Family and domain databases

Gene3D1.50.40.10. 1 hit.
InterProIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSPR00926. MITOCARRIER.
SUPFAMSSF103506. SSF103506. 1 hit.
PROSITEPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio971477.

Entry information

Entry nameRIM2_YEAST
AccessionPrimary (citable) accession number: P38127
Secondary accession number(s): D6VQI6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 16, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome II

Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families