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P38127

- RIM2_YEAST

UniProt

P38127 - RIM2_YEAST

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Protein
Mitochondrial carrier protein RIM2
Gene
RIM2, YBR192W, YBR1402
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. pyrimidine nucleotide transmembrane transporter activity Source: SGD
  2. transporter activity Source: SGD

GO - Biological processi

  1. mitochondrial genome maintenance Source: SGD
  2. pyrimidine nucleotide transport Source: SGD
  3. transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29134-MONOMER.

Protein family/group databases

TCDBi2.A.29.10.4. the mitochondrial carrier (mc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial carrier protein RIM2
Gene namesi
Name:RIM2
Ordered Locus Names:YBR192W
ORF Names:YBR1402
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBR192w.
SGDiS000000396. RIM2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei53 – 7321Helical; Name=1; Reviewed prediction
Add
BLAST
Transmembranei131 – 15121Helical; Name=2; Reviewed prediction
Add
BLAST
Transmembranei179 – 19921Helical; Name=3; Reviewed prediction
Add
BLAST
Transmembranei238 – 25821Helical; Name=4; Reviewed prediction
Add
BLAST
Transmembranei286 – 30621Helical; Name=5; Reviewed prediction
Add
BLAST
Transmembranei347 – 36822Helical; Name=6; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
  3. mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Mitochondrial carrier protein RIM2
PRO_0000090690Add
BLAST

Proteomic databases

MaxQBiP38127.
PaxDbiP38127.

Expressioni

Gene expression databases

GenevestigatoriP38127.

Interactioni

Protein-protein interaction databases

BioGridi32889. 16 interactions.
DIPiDIP-4933N.
MINTiMINT-507683.
STRINGi4932.YBR192W.

Structurei

3D structure databases

ProteinModelPortaliP38127.
SMRiP38127. Positions 53-376.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati50 – 163114Solcar 1
Add
BLAST
Repeati173 – 26290Solcar 2
Add
BLAST
Repeati286 – 37590Solcar 3
Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG301650.
GeneTreeiENSGT00550000074670.
HOGENOMiHOG000188210.
KOiK15116.
OMAiGRQYKNS.
OrthoDBiEOG7N905P.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38127-1 [UniParc]FASTAAdd to Basket

« Hide

MPKKSIEEWE EDAIESVPYL ASDEKGSNYK EATQIPLNLK QSEIENHPTV    50
KPWVHFVAGG IGGMAGAVVT CPFDLVKTRL QSDIFLKAYK SQAVNISKGS 100
TRPKSINYVI QAGTHFKETL GIIGNVYKQE GFRSLFKGLG PNLVGVIPAR 150
SINFFTYGTT KDMYAKAFNN GQETPMIHLM AAATAGWATA TATNPIWLIK 200
TRVQLDKAGK TSVRQYKNSW DCLKSVIRNE GFTGLYKGLS ASYLGSVEGI 250
LQWLLYEQMK RLIKERSIEK FGYQAEGTKS TSEKVKEWCQ RSGSAGLAKF 300
VASIATYPHE VVRTRLRQTP KENGKRKYTG LVQSFKVIIK EEGLFSMYSG 350
LTPHLMRTVP NSIIMFGTWE IVIRLLS 377
Length:377
Mass (Da):42,102
Last modified:October 1, 1994 - v1
Checksum:iA3C61383C3B3743B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z21487 Genomic DNA. Translation: CAA79678.1.
Z36061 Genomic DNA. Translation: CAA85154.1.
AY557871 Genomic DNA. Translation: AAS56197.1.
BK006936 Genomic DNA. Translation: DAA07306.1.
PIRiS36081.
RefSeqiNP_009751.1. NM_001178540.1.

Genome annotation databases

EnsemblFungiiYBR192W; YBR192W; YBR192W.
GeneIDi852491.
KEGGisce:YBR192W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z21487 Genomic DNA. Translation: CAA79678.1 .
Z36061 Genomic DNA. Translation: CAA85154.1 .
AY557871 Genomic DNA. Translation: AAS56197.1 .
BK006936 Genomic DNA. Translation: DAA07306.1 .
PIRi S36081.
RefSeqi NP_009751.1. NM_001178540.1.

3D structure databases

ProteinModelPortali P38127.
SMRi P38127. Positions 53-376.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32889. 16 interactions.
DIPi DIP-4933N.
MINTi MINT-507683.
STRINGi 4932.YBR192W.

Protein family/group databases

TCDBi 2.A.29.10.4. the mitochondrial carrier (mc) family.

Proteomic databases

MaxQBi P38127.
PaxDbi P38127.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YBR192W ; YBR192W ; YBR192W .
GeneIDi 852491.
KEGGi sce:YBR192W.

Organism-specific databases

CYGDi YBR192w.
SGDi S000000396. RIM2.

Phylogenomic databases

eggNOGi NOG301650.
GeneTreei ENSGT00550000074670.
HOGENOMi HOG000188210.
KOi K15116.
OMAi GRQYKNS.
OrthoDBi EOG7N905P.

Enzyme and pathway databases

BioCyci YEAST:G3O-29134-MONOMER.

Miscellaneous databases

NextBioi 971477.

Gene expression databases

Genevestigatori P38127.

Family and domain databases

Gene3Di 1.50.40.10. 1 hit.
InterProi IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view ]
Pfami PF00153. Mito_carr. 3 hits.
[Graphical view ]
PRINTSi PR00926. MITOCARRIER.
SUPFAMi SSF103506. SSF103506. 1 hit.
PROSITEi PS50920. SOLCAR. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "RIM2, MSI1 and PGI1 are located within an 8 kb segment of Saccharomyces cerevisiae chromosome II, which also contains the putative ribosomal gene L21 and a new putative essential gene with a leucine zipper motif."
    Demolis N., Mallet L., Bussereau F., Jacquet M.
    Yeast 9:645-659(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiRIM2_YEAST
AccessioniPrimary (citable) accession number: P38127
Secondary accession number(s): D6VQI6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 14, 2014
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

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