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Protein

Starvation-sensing protein RspB

Gene

rspB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Not known; probable catabolic enzyme.

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi37 – 371Zinc 1; catalyticBy similarity
Metal bindingi59 – 591Zinc 1; catalyticBy similarity
Metal bindingi89 – 891Zinc 2By similarity
Metal bindingi92 – 921Zinc 2By similarity
Metal bindingi95 – 951Zinc 2By similarity
Metal bindingi103 – 1031Zinc 2By similarity
Metal bindingi144 – 1441Zinc 1; catalyticBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:G6838-MONOMER.
ECOL316407:JW1572-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Starvation-sensing protein RspB (EC:1.1.1.-)
Gene namesi
Name:rspB1 Publication
Ordered Locus Names:b1580, JW1572
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12452. rspB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 339339Starvation-sensing protein RspBPRO_0000160900Add
BLAST

Proteomic databases

PaxDbiP38105.

Expressioni

Inductioni

Repressed by RspR.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260232. 14 interactions.
IntActiP38105. 1 interaction.
STRINGi511145.b1580.

Structurei

3D structure databases

ProteinModelPortaliP38105.
SMRiP38105. Positions 1-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CPQ. Bacteria.
COG1063. LUCA.
HOGENOMiHOG000294690.
InParanoidiP38105.
KOiK08322.
OMAiFAVMVEP.
PhylomeDBiP38105.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38105-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSILIEKPN QLAIVEREIP TPSAGEVRVK VKLAGICGSD SHIYRGHNPF
60 70 80 90 100
AKYPRVIGHE FFGVIDAVGE GVESARVGER VAVDPVVSCG HCYPCSIGKP
110 120 130 140 150
NVCTTLAVLG VHADGGFSEY AVVPAKNAWK IPEAVADQYA VMIEPFTIAA
160 170 180 190 200
NVTGHGQPTE NDTVLVYGAG PIGLTIVQVL KGVYNVKNVI VADRIDERLE
210 220 230 240 250
KAKESGADWA INNSQTPLGE IFTEKGIKPT LIIDAACHPS ILKEAVTLAS
260 270 280 290 300
PAARIVLMGF SSEPSEVIQQ GITGKELSIF SSRLNANKFP IVIDWLSKGL
310 320 330
IKPEKLITHT FDFQHVADAI SLFEQDQKHC CKVLLTFSE
Length:339
Mass (Da):36,564
Last modified:October 1, 1994 - v1
Checksum:iE0A1062DFB7C114E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L31628 Genomic DNA. Translation: AAA21686.1.
U00096 Genomic DNA. Translation: AAC74652.1.
AP009048 Genomic DNA. Translation: BAA15284.1.
PIRiI81185.
RefSeqiNP_416097.1. NC_000913.3.
WP_000836066.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74652; AAC74652; b1580.
BAA15284; BAA15284; BAA15284.
GeneIDi946127.
KEGGiecj:JW1572.
eco:b1580.
PATRICi32118462. VBIEscCol129921_1651.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L31628 Genomic DNA. Translation: AAA21686.1.
U00096 Genomic DNA. Translation: AAC74652.1.
AP009048 Genomic DNA. Translation: BAA15284.1.
PIRiI81185.
RefSeqiNP_416097.1. NC_000913.3.
WP_000836066.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP38105.
SMRiP38105. Positions 1-337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260232. 14 interactions.
IntActiP38105. 1 interaction.
STRINGi511145.b1580.

Proteomic databases

PaxDbiP38105.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74652; AAC74652; b1580.
BAA15284; BAA15284; BAA15284.
GeneIDi946127.
KEGGiecj:JW1572.
eco:b1580.
PATRICi32118462. VBIEscCol129921_1651.

Organism-specific databases

EchoBASEiEB2346.
EcoGeneiEG12452. rspB.

Phylogenomic databases

eggNOGiENOG4105CPQ. Bacteria.
COG1063. LUCA.
HOGENOMiHOG000294690.
InParanoidiP38105.
KOiK08322.
OMAiFAVMVEP.
PhylomeDBiP38105.

Enzyme and pathway databases

BioCyciEcoCyc:G6838-MONOMER.
ECOL316407:JW1572-MONOMER.

Miscellaneous databases

PROiP38105.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRSPB_ECOLI
AccessioniPrimary (citable) accession number: P38105
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.