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Protein

Carrier protein YMC2, mitochondrial

Gene

YMC2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • organic acid transmembrane transporter activity Source: SGD

GO - Biological processi

  • mitochondrial transport Source: SGD
  • transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29066-MONOMER.
ReactomeiR-SCE-70635. Urea cycle.

Protein family/group databases

TCDBi2.A.29.8.11. the mitochondrial carrier (mc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Carrier protein YMC2, mitochondrial
Gene namesi
Name:YMC2
Ordered Locus Names:YBR104W
ORF Names:YBR0833
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR104W.
SGDiS000000308. YMC2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 58Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei84 – 104Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei140 – 160Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei205 – 225Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei243 – 263Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei297 – 318Helical; Name=1Sequence analysisAdd BLAST22

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: UniProtKB-SubCell
  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 33MitochondrionSequence analysisAdd BLAST33
ChainiPRO_000001926634 – 329Carrier protein YMC2, mitochondrialAdd BLAST296

Proteomic databases

MaxQBiP38087.
PRIDEiP38087.

Interactioni

Protein-protein interaction databases

BioGridi32808. 33 interactors.
IntActiP38087. 6 interactors.
MINTiMINT-4477096.

Structurei

3D structure databases

ProteinModelPortaliP38087.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati34 – 115Solcar 1Add BLAST82
Repeati143 – 226Solcar 2Add BLAST84
Repeati238 – 325Solcar 3Add BLAST88

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00860000134541.
HOGENOMiHOG000168307.
InParanoidiP38087.
KOiK15109.
OMAiGSYPFDV.
OrthoDBiEOG092C3R9J.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38087-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEFPTPQL LDELEDQQKV TTPNEKRELS SNRVLKDIFA GTIGGIAQVL
60 70 80 90 100
VGQPFDTTKV RLQTATTRTT TLEVLRNLVK NEGVFAFYKG ALTPLLGVGI
110 120 130 140 150
CVSVQFGVNE AMKRFFQNYN ASKNPNMSSQ DVDLSRSNTL PLSQYYVCGL
160 170 180 190 200
TGGVVNSFLA SPIEQIRIRL QTQTSNGGDR EFKGPWDCIK KLKAQGGLMR
210 220 230 240 250
GLFPTMIRAG HGLGTYFLVY EALVAREIGT GLTRNEIPPW KLCLFGAFSG
260 270 280 290 300
TMLWLTVYPL DVVKSIIQND DLRKPKYKNS ISYVAKTIYA KEGIRAFFKG
310 320
FGPTMVRSAP VNGATFLTFE LVMRFLGEE
Length:329
Mass (Da):36,555
Last modified:October 1, 1994 - v1
Checksum:i0F5139F39D89ED13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78993 Genomic DNA. Translation: CAA55607.1.
Z35973 Genomic DNA. Translation: CAA85059.1.
AY693055 Genomic DNA. Translation: AAT93074.1.
BK006936 Genomic DNA. Translation: DAA07223.1.
PIRiS48269.
RefSeqiNP_009662.3. NM_001178452.3.

Genome annotation databases

EnsemblFungiiYBR104W; YBR104W; YBR104W.
GeneIDi852401.
KEGGisce:YBR104W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78993 Genomic DNA. Translation: CAA55607.1.
Z35973 Genomic DNA. Translation: CAA85059.1.
AY693055 Genomic DNA. Translation: AAT93074.1.
BK006936 Genomic DNA. Translation: DAA07223.1.
PIRiS48269.
RefSeqiNP_009662.3. NM_001178452.3.

3D structure databases

ProteinModelPortaliP38087.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32808. 33 interactors.
IntActiP38087. 6 interactors.
MINTiMINT-4477096.

Protein family/group databases

TCDBi2.A.29.8.11. the mitochondrial carrier (mc) family.

Proteomic databases

MaxQBiP38087.
PRIDEiP38087.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR104W; YBR104W; YBR104W.
GeneIDi852401.
KEGGisce:YBR104W.

Organism-specific databases

EuPathDBiFungiDB:YBR104W.
SGDiS000000308. YMC2.

Phylogenomic databases

GeneTreeiENSGT00860000134541.
HOGENOMiHOG000168307.
InParanoidiP38087.
KOiK15109.
OMAiGSYPFDV.
OrthoDBiEOG092C3R9J.

Enzyme and pathway databases

BioCyciYEAST:G3O-29066-MONOMER.
ReactomeiR-SCE-70635. Urea cycle.

Miscellaneous databases

PROiP38087.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYMC2_YEAST
AccessioniPrimary (citable) accession number: P38087
Secondary accession number(s): D6VQA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: November 30, 2016
This is version 137 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1050 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.