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Protein

Carrier protein YMC2, mitochondrial

Gene

YMC2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 1050 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • organic acid transmembrane transporter activity Source: SGD

GO - Biological processi

  • mitochondrial transport Source: SGD
  • transmembrane transport Source: SGD

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciYEAST:G3O-29066-MONOMER

Protein family/group databases

TCDBi2.A.29.8.11 the mitochondrial carrier (mc) family

Names & Taxonomyi

Protein namesi
Recommended name:
Carrier protein YMC2, mitochondrial
Gene namesi
Name:YMC2
Ordered Locus Names:YBR104W
ORF Names:YBR0833
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR104W
SGDiS000000308 YMC2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 58Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei84 – 104Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei140 – 160Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei205 – 225Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei243 – 263Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei297 – 318Helical; Name=1Sequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 33MitochondrionSequence analysisAdd BLAST33
ChainiPRO_000001926634 – 329Carrier protein YMC2, mitochondrialAdd BLAST296

Proteomic databases

MaxQBiP38087
PaxDbiP38087
PRIDEiP38087

Interactioni

Protein-protein interaction databases

BioGridi3280880 interactors.
IntActiP38087 6 interactors.
STRINGi4932.YBR104W

Structurei

3D structure databases

ProteinModelPortaliP38087
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati34 – 115Solcar 1Add BLAST82
Repeati143 – 226Solcar 2Add BLAST84
Repeati238 – 325Solcar 3Add BLAST88

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00700000104295
HOGENOMiHOG000168307
InParanoidiP38087
KOiK15109
OMAiPPRYKGV
OrthoDBiEOG092C3R9J

Family and domain databases

Gene3Di1.50.40.102 hits
InterProiView protein in InterPro
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38087-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEFPTPQL LDELEDQQKV TTPNEKRELS SNRVLKDIFA GTIGGIAQVL
60 70 80 90 100
VGQPFDTTKV RLQTATTRTT TLEVLRNLVK NEGVFAFYKG ALTPLLGVGI
110 120 130 140 150
CVSVQFGVNE AMKRFFQNYN ASKNPNMSSQ DVDLSRSNTL PLSQYYVCGL
160 170 180 190 200
TGGVVNSFLA SPIEQIRIRL QTQTSNGGDR EFKGPWDCIK KLKAQGGLMR
210 220 230 240 250
GLFPTMIRAG HGLGTYFLVY EALVAREIGT GLTRNEIPPW KLCLFGAFSG
260 270 280 290 300
TMLWLTVYPL DVVKSIIQND DLRKPKYKNS ISYVAKTIYA KEGIRAFFKG
310 320
FGPTMVRSAP VNGATFLTFE LVMRFLGEE
Length:329
Mass (Da):36,555
Last modified:October 1, 1994 - v1
Checksum:i0F5139F39D89ED13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78993 Genomic DNA Translation: CAA55607.1
Z35973 Genomic DNA Translation: CAA85059.1
AY693055 Genomic DNA Translation: AAT93074.1
BK006936 Genomic DNA Translation: DAA07223.1
PIRiS48269
RefSeqiNP_009662.3, NM_001178452.3

Genome annotation databases

EnsemblFungiiYBR104W; YBR104W; YBR104W
GeneIDi852401
KEGGisce:YBR104W

Similar proteinsi

Entry informationi

Entry nameiYMC2_YEAST
AccessioniPrimary (citable) accession number: P38087
Secondary accession number(s): D6VQA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: March 28, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome