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Protein

Protein YRO2

Gene

YRO2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29025-MONOMER.

Protein family/group databases

TCDBi3.E.1.4.8. the ion-translocating microbial rhodopsin (mr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YRO2
Gene namesi
Name:YRO2
Ordered Locus Names:YBR054W
ORF Names:YBR0507
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR054W.
SGDiS000000258. YRO2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34ExtracellularSequence analysisAdd BLAST34
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Topological domaini56 – 62CytoplasmicSequence analysis7
Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Topological domaini84 – 119ExtracellularSequence analysisAdd BLAST36
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Topological domaini141CytoplasmicSequence analysis1
Transmembranei142 – 162HelicalSequence analysisAdd BLAST21
Topological domaini163 – 172ExtracellularSequence analysis10
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 202CytoplasmicSequence analysis9
Transmembranei203 – 223HelicalSequence analysisAdd BLAST21
Topological domaini224 – 238ExtracellularSequence analysisAdd BLAST15
Transmembranei239 – 259HelicalSequence analysisAdd BLAST21
Topological domaini260 – 344CytoplasmicSequence analysisAdd BLAST85

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001962861 – 344Protein YRO2Add BLAST344

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki286Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Modified residuei293PhosphoserineCombined sources1
Modified residuei341PhosphothreonineCombined sources1
Modified residuei343PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiP38079.
PRIDEiP38079.

PTM databases

iPTMnetiP38079.

Interactioni

Protein-protein interaction databases

BioGridi32755. 31 interactors.
DIPiDIP-4184N.
IntActiP38079. 11 interactors.
MINTiMINT-524121.

Structurei

3D structure databases

ProteinModelPortaliP38079.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi304 – 331Lys-richAdd BLAST28
Compositional biasi334 – 344Glu-richAdd BLAST11

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000004481.
HOGENOMiHOG000248243.
InParanoidiP38079.
OMAiPLWQIAF.
OrthoDBiEOG092C44CH.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhodopsins.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDYVELLKR GGNEAIKINP PTGADFHITS RGSDWLFTVF CVNLLFGVIL
60 70 80 90 100
VPLMFRKPVK DRFVYYTAIA PNLFMSIAYF TMASNLGWIP VRAKYNHVQT
110 120 130 140 150
STQKEHPGYR QIFYARYVGW FLAFPWPIIQ MSLLGGTPLW QIAFNVGMTE
160 170 180 190 200
IFTVCWLIAA CVHSTYKWGY YTIGIGAAIV VCISLMTTTF NLVKARGKDV
210 220 230 240 250
SNVFITFMSV IMFLWLIAYP TCFGITDGGN VLQPDSATIF YGIIDLLILS
260 270 280 290 300
ILPVLFMPLA NYLGIERLGL IFDEEPAEHV GPVAEKKMPS PASFKSSDSD
310 320 330 340
SSIKEKLKLK KKHKKDKKKA KKAKKAKKAK KAQEEEEDVA TDSE
Length:344
Mass (Da):38,720
Last modified:October 1, 1994 - v1
Checksum:iBF63AC0398A0B566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46260 Genomic DNA. Translation: CAA86397.1.
Z35923 Genomic DNA. Translation: CAA84997.1.
BK006936 Genomic DNA. Translation: DAA07173.1.
PIRiS45912.
RefSeqiNP_009610.1. NM_001178402.1.

Genome annotation databases

EnsemblFungiiYBR054W; YBR054W; YBR054W.
GeneIDi852343.
KEGGisce:YBR054W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46260 Genomic DNA. Translation: CAA86397.1.
Z35923 Genomic DNA. Translation: CAA84997.1.
BK006936 Genomic DNA. Translation: DAA07173.1.
PIRiS45912.
RefSeqiNP_009610.1. NM_001178402.1.

3D structure databases

ProteinModelPortaliP38079.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32755. 31 interactors.
DIPiDIP-4184N.
IntActiP38079. 11 interactors.
MINTiMINT-524121.

Protein family/group databases

TCDBi3.E.1.4.8. the ion-translocating microbial rhodopsin (mr) family.

PTM databases

iPTMnetiP38079.

Proteomic databases

MaxQBiP38079.
PRIDEiP38079.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR054W; YBR054W; YBR054W.
GeneIDi852343.
KEGGisce:YBR054W.

Organism-specific databases

EuPathDBiFungiDB:YBR054W.
SGDiS000000258. YRO2.

Phylogenomic databases

GeneTreeiENSGT00390000004481.
HOGENOMiHOG000248243.
InParanoidiP38079.
OMAiPLWQIAF.
OrthoDBiEOG092C44CH.

Enzyme and pathway databases

BioCyciYEAST:G3O-29025-MONOMER.

Miscellaneous databases

PROiP38079.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhodopsins.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYRO2_YEAST
AccessioniPrimary (citable) accession number: P38079
Secondary accession number(s): D6VQ53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: November 2, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1950 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.