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P38058 (CBPA_CLOCL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cellulose-binding protein A
Gene names
Name:cbpA
OrganismClostridium cellulovorans
Taxonomic identifier1493 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length1848 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Function

Binds to cellulose fibers and coordinates cellulase enzymes.

Subcellular location

Secreted. Note: Remains at the cell surface.

Post-translational modification

The N-terminus is blocked.

Glycosylated Probable.

Sequence similarities

Contains 1 CBM3 (carbohydrate binding type-3) domain.

Contains 9 cohesin domains.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainRepeat
Signal
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcellular cell wall organization

Inferred from electronic annotation. Source: UniProtKB-KW

cellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncarbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828 Potential
Chain29 – 18481820Cellulose-binding protein A
PRO_0000020846

Regions

Domain29 – 190162CBM3
Domain291 – 428138Cohesin 1
Domain435 – 570136Cohesin 2
Domain668 – 801134Cohesin 3
Domain810 – 943134Cohesin 4
Domain952 – 1085134Cohesin 5
Domain1094 – 1227134Cohesin 6
Domain1236 – 1369134Cohesin 7
Domain1377 – 1511135Cohesin 8
Domain1709 – 1847139Cohesin 9

Sequences

Sequence LengthMass (Da)Tools
P38058 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 85FA6CE6F771AF1A

FASTA1,848189,152
        10         20         30         40         50         60 
MQKKKSLNLL LALMMVFALV LPSIPALAAT SSMSVEFYNS NKSAQTNSIT PIIKITNTSD 

        70         80         90        100        110        120 
SDLNLNDVKV RYYYTSDGTQ GQTFWCDHAG ALLGNSYVDN TSKVTANFVK ETASPTSTYD 

       130        140        150        160        170        180 
TYVEFGFASG RATLKKGQFI TIQGRITKSD WSNYTQTNDY SFDASSSTPV VNPKVTGYIG 

       190        200        210        220        230        240 
GAKVLGTAPG PDVPSSIINP TSATFDKNVT KQADVKTTMT LNGNTFKTIT DANGTALNAS 

       250        260        270        280        290        300 
TDYSVSGNDV TISKAYLAKQ SVGTTTLNFN FSAGNPQKLV ITVVDTPVEA VTATIGKVQV 

       310        320        330        340        350        360 
NAGETVAVPV NLTKVPAAGL ATIELPLTFD SASLEVVSIT AGDIVLNPSV NFSSTVSGST 

       370        380        390        400        410        420 
IKLLFLDDTL GSQLITKDGV FATITFKAKA ITGTTAKVTS VKLAGTPVVG DAQLQEKPCA 

       430        440        450        460        470        480 
VNPGTVTINP IDNRMQISVG TATVKAGEIA AVPVTLTSVP STGIATAEAQ VSFDATLLEV 

       490        500        510        520        530        540 
ASVTAGDIVL NPTVNFSYTV NGNVIKLLFL DDTLGSQLIS KDGVFVTINF KAKAVTSTVT 

       550        560        570        580        590        600 
TPVTVSGTPV FADGTLAEVQ SKTAAGSVTI NIGDPILEPT ISPVTATFDK KAPADVATTM 

       610        620        630        640        650        660 
TLNGYTFNGI TGLTTSDYSI SGNVVKISQA YLAKQPVGDL TLTFNFSNGN KTATAKLVVS 

       670        680        690        700        710        720 
IKDAPKTVTA TVGTATVNAG ETVAVPVTLS NVSGISTAEL QLSFDATLLE VVSITAGDIV 

       730        740        750        760        770        780 
LNPSVNFSSV VNGSTIKLLF LDDTLGSQLI SKDGVFATIN FKAKSVTSTV TTPVKVSGTP 

       790        800        810        820        830        840 
VFADGTLAEL SYETVAGSVT INAIGPVKTV TATVGTATVK SGETVAVPVT LSNVPGIATA 

       850        860        870        880        890        900 
ELQLSFDATL LEVASITVGD IVLNPSVNFS SVVNGSTIKL LFLDDTLGSQ LISKDGVLAT 

       910        920        930        940        950        960 
INFKAKTVTS TVTTPVAVSG TPVFADGTLA ELQSKTVAGS VTIEPSQPVK TVTATVGTAT 

       970        980        990       1000       1010       1020 
VKSGETVAVP VTLSNVPGIA TAELQVGFDA TLLEVASITV GDIVLNPSVN FSSVVNGSTI 

      1030       1040       1050       1060       1070       1080 
KLLFLDDTLG SQLISKDGVL ATINFKAKTV TSKVTTPVAV SGTPVFADGT LAELNMKTVA 

      1090       1100       1110       1120       1130       1140 
GSVTIEPSQP VKTVTATVGT ATVKSGETVA VPVTLSNVPG IATAELQVGF DATLLEVASI 

      1150       1160       1170       1180       1190       1200 
TVGDIVLNPS VNFSSVVNGS TIKLLFLDDT LGSQLISKDG VLATINFKAK TVTSKVTTPV 

      1210       1220       1230       1240       1250       1260 
AVSGTPVFAD GTLAELKYET VAGSVTIEPS QPVKTVTATV GTATGKVGET VAVPVTLSNV 

      1270       1280       1290       1300       1310       1320 
PGIATAEVQV GFDATLLEVA SITAGDIVLN PSVNFSSVVN GSTIKILFLD DTLGSQLISK 

      1330       1340       1350       1360       1370       1380 
DGVFATINFK IKAVPSTGTT PVAISGTPVF ADGTLAEVQY KTVAGSVTIA AADIKAVKAT 

      1390       1400       1410       1420       1430       1440 
VGTATGKAGD TVAVPVTLSN VSGIATVELQ LSFDATLLEV ASITAGDIVL NPSVNFSSVV 

      1450       1460       1470       1480       1490       1500 
NGSTIKILFL DDTLGSQLIS KDGVFATVNF KVKSTATNSA VTPVTVSGTP VFADGTLAEL 

      1510       1520       1530       1540       1550       1560 
KSESAAGRLT ILPTVIIVDS TVAPTAVTFD KANQADAAIT MTLNGNTFSA IKNGTATLVK 

      1570       1580       1590       1600       1610       1620 
GTDYTVSENV VTISKAYLAK QTGTVTLEFV FDKGNSAKVV VAVKEIQIVN STITPVVATF 

      1630       1640       1650       1660       1670       1680 
EKTAAKQADV VVTMSLNGNT FSAIKNGTTT LVKGTDYTIS GSTVTISKAY LATLADGSAT 

      1690       1700       1710       1720       1730       1740 
LEFVFNQGAS AKLRLTIVPA VVDPVVTDFA VKIDKVSAAA GSTVKVPVSL INVSKVGNVC 

      1750       1760       1770       1780       1790       1800 
VAEYKISFDS SVLTYVGTTA GTSIKNPAVN FSSQLNGNTI TLLFFDNTIG NELITADGQF 

      1810       1820       1830       1840 
ATIEFKVNAA ATSGTTAEVK VATISSFADA SLTEITKVAT VNGSVKVS

« Hide

References

[1]"Primary sequence analysis of Clostridium cellulovorans cellulose binding protein A."
Shoseyov O., Takagi M., Goldstein M.A., Doi R.H.
Proc. Natl. Acad. Sci. U.S.A. 89:3483-3487(1992) [PubMed: 1565642] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M73817 Genomic DNA. Translation: AAA23218.1.
PIRA44140.

3D structure databases

ProteinModelPortalP38058.
SMRP38058. Positions 471-532.
ModBaseSearch...

Protein family/group databases

CAZyCBM3. Carbohydrate-Binding Module Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR008965. Carb-bd_dom.
IPR001956. CBD_3.
IPR002102. Cohesin_dom.
IPR018452. Cohesin_dom_subgr.
IPR005102. DUF291.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
Gene3DG3DSA:2.60.40.710. CBD_3. 1 hit.
G3DSA:2.60.40.680. Cohesin. 9 hits.
G3DSA:2.60.40.10. Ig-like_fold. 4 hits.
PfamPF00942. CBM_3. 1 hit.
PF00963. Cohesin. 9 hits.
PF03442. DUF291. 4 hits.
[Graphical view]
SMARTSM01067. CBM_3. 1 hit.
[Graphical view]
SUPFAMSSF49384. Cellul_bind. 10 hits.
SSF81296. Ig_E-set. 4 hits.
PROSITEPS51172. CBM3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCBPA_CLOCL
AccessionPrimary (citable) accession number: P38058
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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