SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P38041

- BOB1_YEAST

UniProt

P38041 - BOB1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Protein BOB1
Gene
BOI1, BOB1, GIN7, YBL085W, YBL0717
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Binds to the BEM1 protein.

GO - Molecular functioni

  1. phospholipid binding Source: SGD
  2. protein binding Source: IntAct

GO - Biological processi

  1. budding cell apical bud growth Source: SGD
  2. cytokinesis, completion of separation Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-28974-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BOB1
Alternative name(s):
BEM1-binding protein
Growth inhibitory protein 7
Gene namesi
Name:BOI1
Synonyms:BOB1, GIN7
Ordered Locus Names:YBL085W
ORF Names:YBL0717
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome II

Organism-specific databases

CYGDiYBL085w.
SGDiS000000181. BOI1.

Subcellular locationi

GO - Cellular componenti

  1. cellular bud Source: SGD
  2. cellular bud neck Source: SGD
  3. site of polarized growth Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 980980Protein BOB1
PRO_0000064968Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei104 – 1041Phosphoserine2 Publications
Modified residuei106 – 1061Phosphoserine1 Publication
Modified residuei128 – 1281Phosphoserine1 Publication
Modified residuei151 – 1511Phosphothreonine1 Publication
Modified residuei158 – 1581Phosphothreonine1 Publication
Modified residuei209 – 2091Phosphoserine3 Publications
Modified residuei393 – 3931Phosphoserine1 Publication
Modified residuei412 – 4121Phosphoserine1 Publication
Modified residuei525 – 5251Phosphoserine1 Publication
Modified residuei528 – 5281Phosphoserine2 Publications
Modified residuei589 – 5891Phosphoserine1 Publication
Modified residuei590 – 5901Phosphoserine1 Publication
Modified residuei593 – 5931Phosphoserine1 Publication
Modified residuei644 – 6441Phosphoserine2 Publications
Modified residuei655 – 6551Phosphoserine1 Publication
Modified residuei735 – 7351Phosphoserine1 Publication
Modified residuei919 – 9191Phosphothreonine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP38041.
PaxDbiP38041.
PRIDEiP38041.

Expressioni

Gene expression databases

GenevestigatoriP38041.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BEM1P293665EBI-3719,EBI-3508
CDC14Q006842EBI-3719,EBI-4192
FIR1P400202EBI-3719,EBI-13431
NBA1Q082293EBI-3719,EBI-36841
YDR239CQ037802EBI-3719,EBI-30094
YER158CP400954EBI-3719,EBI-22734
YJR056CP471153EBI-3719,EBI-25514
ZDS2P547863EBI-3719,EBI-29637

Protein-protein interaction databases

BioGridi32619. 91 interactions.
DIPiDIP-2226N.
IntActiP38041. 72 interactions.
MINTiMINT-584486.
STRINGi4932.YBL085W.

Structurei

3D structure databases

ProteinModelPortaliP38041.
SMRiP38041. Positions 14-75, 781-902.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 7765SH3
Add
BLAST
Domaini228 – 29265SAM
Add
BLAST
Domaini776 – 895120PH
Add
BLAST

Sequence similaritiesi

Contains 1 PH domain.
Contains 1 SH3 domain.

Keywords - Domaini

SH3 domain

Phylogenomic databases

eggNOGiNOG73665.
GeneTreeiENSGT00530000066577.
HOGENOMiHOG000066063.
OMAiYVQRPST.
OrthoDBiEOG7N63W3.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF07647. SAM_2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00454. SAM. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS50105. SAM_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38041-1 [UniParc]FASTAAdd to Basket

« Hide

MSLEGNTLGK GAKSFPLYIA VNQYSKRMED ELNMKPGDKI KVITDDGEYN    50
DGWYYGRNLR TKEEGLYPAV FTKRIAIEKP ENLHKSPTQE SGNSGVKYGN 100
LNDSASNIGK VSSHQQENRY TSLKSTMSDI DKALEELRSG SVEQEVSKSP 150
TRVPEVSTPQ LQDEQTLIQE KTRNEENTTH DSLFSSTADL NLSSESLKNI 200
SKSNISTKSL EPSSESVRQL DLKMAKSWSP EEVTDYFSLV GFDQSTCNKF 250
KEHQVSGKIL LELELEHLKE LEINSFGIRF QIFKEIRNIK SAIDSSSNKL 300
DADYSTFAFE NQAAQLMPAA TVNRDEIQQQ ISSKCNKLSS ESSDRKSSSV 350
TTELQRPSSV VVNPNFKLHD PAEQILDMTE VPNLFADKDI FESPGRAPKP 400
PSYPSPVQPP QSPSFNNRYT NNNARFPPQT TYPPKNKNPT VYSNGLIPNS 450
STSSDNSTGK FKFPAMNGHD SNSRKTTLTS ATIPSINTVN TDESLPAISN 500
ISSNATSHHP NRNSVVYNNH KRTESGSSFV DLFNRISMLS PVKSSFDEEE 550
TKQPSKASRA VFDSARRKSS YGHSRDASLS EMKKHRRNSS ILSFFSSKSQ 600
SNPTSPTKQT FTIDPAKMTS HSRSQSNSYS HARSQSYSHS RKHSLVTSPL 650
KTSLSPINSK SNIALAHSET PTSSNNKEAV SQPSEGKHKH KHKHKSKHKH 700
KNSSSKDGSS EEKSKKKLFS STKESFVGSK EFKRSPSELT QKSTKSILPR 750
SNAKKQQTSA FTEGIRSITA KESMQTADCS GWMSKKGTGA MGTWKQRFFT 800
LHGTRLSYFT NTNDEKERGL IDITAHRVLP ASDDDRLISL YAASLGKGKY 850
CFKLVPPQPG SKKGLTFTEP RVHYFAVENK SEMKAWLSAI IKATIDIDTS 900
VPVISSYATP TIPLSKAQTL LEEARLQTQL RDAEEEEGRD QFGWDDTQNK 950
RNSNYPIEQD QFETSDYLES SAFEYPGGRL 980
Length:980
Mass (Da):109,295
Last modified:October 1, 1994 - v1
Checksum:i09F1DD1F9EF30F36
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L31406 Genomic DNA. Translation: AAB08439.1.
X79489 Genomic DNA. Translation: CAA56021.1.
Z35846 Genomic DNA. Translation: CAA84906.1.
BK006936 Genomic DNA. Translation: DAA07039.1.
PIRiS45444.
RefSeqiNP_009468.1. NM_001178325.1.

Genome annotation databases

EnsemblFungiiYBL085W; YBL085W; YBL085W.
GeneIDi852193.
KEGGisce:YBL085W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L31406 Genomic DNA. Translation: AAB08439.1 .
X79489 Genomic DNA. Translation: CAA56021.1 .
Z35846 Genomic DNA. Translation: CAA84906.1 .
BK006936 Genomic DNA. Translation: DAA07039.1 .
PIRi S45444.
RefSeqi NP_009468.1. NM_001178325.1.

3D structure databases

ProteinModelPortali P38041.
SMRi P38041. Positions 14-75, 781-902.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32619. 91 interactions.
DIPi DIP-2226N.
IntActi P38041. 72 interactions.
MINTi MINT-584486.
STRINGi 4932.YBL085W.

Proteomic databases

MaxQBi P38041.
PaxDbi P38041.
PRIDEi P38041.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YBL085W ; YBL085W ; YBL085W .
GeneIDi 852193.
KEGGi sce:YBL085W.

Organism-specific databases

CYGDi YBL085w.
SGDi S000000181. BOI1.

Phylogenomic databases

eggNOGi NOG73665.
GeneTreei ENSGT00530000066577.
HOGENOMi HOG000066063.
OMAi YVQRPST.
OrthoDBi EOG7N63W3.

Enzyme and pathway databases

BioCyci YEAST:G3O-28974-MONOMER.

Miscellaneous databases

NextBioi 970676.

Gene expression databases

Genevestigatori P38041.

Family and domain databases

Gene3Di 1.10.150.50. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00169. PH. 1 hit.
PF07647. SAM_2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view ]
SMARTi SM00233. PH. 1 hit.
SM00454. SAM. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF47769. SSF47769. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS50003. PH_DOMAIN. 1 hit.
PS50105. SAM_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in Yeast."
    Bender L., Lo H.S., Lee H., Kokojan V., Peterson V., Bender A.
    J. Cell Biol. 133:879-894(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II."
    Obermaier B., Gassenhuber J., Piravandi E., Domdey H.
    Yeast 11:1103-1112(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway."
    Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N.
    Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: YAL6B.
  7. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-104; SER-209; SER-528; SER-644 AND THR-919, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  8. "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
    Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
    Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-735, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-655, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-104; SER-106; SER-128; THR-151; THR-158; SER-209; SER-393; SER-412; SER-525; SER-528; SER-589; SER-590; SER-593 AND SER-644, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiBOB1_YEAST
AccessioniPrimary (citable) accession number: P38041
Secondary accession number(s): D6VPR9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: September 3, 2014
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1040 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

Similar proteinsi