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P37986

- G6PD_DICD3

UniProt

P37986 - G6PD_DICD3

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Protein
Glucose-6-phosphate 1-dehydrogenase
Gene
zwf, Dda3937_03574
Organism
Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity.UniRule annotation

Catalytic activityi

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei50 – 501NADP By similarity
Binding sitei147 – 1471NADP By similarity
Binding sitei177 – 1771Substrate By similarity
Binding sitei181 – 1811Substrate By similarity
Binding sitei215 – 2151Substrate By similarity
Binding sitei234 – 2341Substrate By similarity
Active sitei239 – 2391Proton acceptor By similarity
Binding sitei339 – 3391Substrate By similarity
Binding sitei344 – 3441Substrate By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi92 – 932NADP By similarity

GO - Molecular functioni

  1. NADP binding Source: UniProtKB-HAMAP
  2. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciDDAD198628:GHFQ-2203-MONOMER.
UniPathwayiUPA00115; UER00408.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate 1-dehydrogenase (EC:1.1.1.49)
Short name:
G6PD
Gene namesi
Name:zwf
Ordered Locus Names:Dda3937_03574
OrganismiDickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Taxonomic identifieri198628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
ProteomesiUP000006859: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 491491Glucose-6-phosphate 1-dehydrogenaseUniRule annotation
PRO_0000068121Add
BLAST

Proteomic databases

PRIDEiP37986.

Structurei

3D structure databases

ProteinModelPortaliP37986.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000046191.
KOiK00036.
OMAiYCVTAVS.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.
TIGRFAMsiTIGR00871. zwf. 1 hit.
PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37986-1 [UniParc]FASTAAdd to Basket

« Hide

MAVTSTAQAC DLVIFGAKGD LARRKLLPSL YQLEKAGHIH PETRIIGVGR    50
AEWDRDAYIK VVREALETFL KEPLDPALWT TLSNRLDFCN LDVEDTEGFK 100
RLGTMLDQQN RTTINYFAMP PSTFGAICRG LGQAGLNKEP ARVVMEKPLG 150
TNLASSRVIN NQVAEFFNEC QVYRIDHYLG KETVLNLLAL RFANSLFANN 200
WDNRTIDHVQ ITVAEEVGIE GRWGYFDQAG QMRDMIQNHL LQILTMIAMS 250
PPADLSTDRI RDEKVKVLRS LRRIDRSNVH EVTVRGQYTS GFVQGKKVPG 300
YLEEEGANKT SNTETFVAIR VDIDDWRWSG VPFYLRTGKR LPSKCSEVVV 350
YFKNPALNLF HDSYQQLPQN KLIIRLQPDE GVEIQILNKI PGLDHKHRLQ 400
TTKLDLSFSE TFNQQHLADA YERLLLETMR GIQALFVRRD EVEEAWKWVD 450
SIMDAWAMDN DSPKPYQAGT WGPVASVAMI TRDGRSWNEV E 491
Length:491
Mass (Da):56,034
Last modified:October 1, 1994 - v1
Checksum:i67BE0D8DCA97D5A6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74866 Genomic DNA. Translation: CAA52858.1.
CP002038 Genomic DNA. Translation: ADM98358.1.
PIRiS37053.
RefSeqiYP_003882915.1. NC_014500.1.

Genome annotation databases

EnsemblBacteriaiADM98358; ADM98358; Dda3937_03574.
GeneIDi9733588.
KEGGiddd:Dda3937_03574.
PATRICi42316622. VBIDicDad25310_2134.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74866 Genomic DNA. Translation: CAA52858.1 .
CP002038 Genomic DNA. Translation: ADM98358.1 .
PIRi S37053.
RefSeqi YP_003882915.1. NC_014500.1.

3D structure databases

ProteinModelPortali P37986.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P37986.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADM98358 ; ADM98358 ; Dda3937_03574 .
GeneIDi 9733588.
KEGGi ddd:Dda3937_03574.
PATRICi 42316622. VBIDicDad25310_2134.

Phylogenomic databases

HOGENOMi HOG000046191.
KOi K00036.
OMAi YCVTAVS.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00408 .
BioCyci DDAD198628:GHFQ-2203-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00966. G6PD.
InterProi IPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR23429. PTHR23429. 1 hit.
Pfami PF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000110. G6PD. 1 hit.
PRINTSi PR00079. G6PDHDRGNASE.
TIGRFAMsi TIGR00871. zwf. 1 hit.
PROSITEi PS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of the Erwinia chrysanthemi region containing the kdgA and zwf genes."
    Hugouvieux-Cotte-Pattat N., Robert-Baudouy J.
    Mol. Microbiol. 11:67-75(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 3937.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 3937.

Entry informationi

Entry nameiG6PD_DICD3
AccessioniPrimary (citable) accession number: P37986
Secondary accession number(s): E0SB89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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