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Protein

RNA polymerase sigma-F factor

Gene

sigF

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal spore maturation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi254 – 273H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma-F factor
Gene namesi
Name:sigF
Synonyms:rpoX
Ordered Locus Names:SCO4035
ORF Names:2SCD60.01c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000939801 – 287RNA polymerase sigma-F factorAdd BLAST287

Interactioni

Protein-protein interaction databases

IntActiP37971, 1 interactor
STRINGi100226.SCO4035

Structurei

3D structure databases

ProteinModelPortaliP37971
SMRiP37971
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi91 – 104Polymerase core bindingAdd BLAST14

Sequence similaritiesi

Belongs to the sigma-70 factor family. SigB subfamily.Curated

Phylogenomic databases

eggNOGiENOG4108N6D Bacteria
COG1191 LUCA
HOGENOMiHOG000270270
InParanoidiP37971
KOiK03090
OMAiVVQVGTI
OrthoDBiPOG091H09IG
PhylomeDBiP37971

Family and domain databases

Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR014322 RNA_pol_sigma-B/F/G
IPR000943 RNA_pol_sigma70
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02980 SigBFG, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit

Sequencei

Sequence statusi: Complete.

P37971-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPASTAPQAP PAPPAQAQAQ APAQAQEAPA PQRSRGADTR ALTQVLFGEL
60 70 80 90 100
KGLAPGTPEH DRVRAALIEA NLPLVRYAAA RFRSRNEPME DVVQVGTIGL
110 120 130 140 150
INAIDRFDPE RGVQFPTFAM PTVVGEIKRY FRDNVRTVHV PRRLHELWVQ
160 170 180 190 200
VNSATEDLTT AFGRSPTTAE IAERLRITEE EVLSCIEAGR SYHATSLEAA
210 220 230 240 250
QEGDGLPGLL DRLGYEDPAL DGVEHRDLVR HLLVQLPERE QRILLLRYYS
260 270 280
NLTQSQISAE LGVSQMHVSR LLARSFQRLR SANRIDA
Length:287
Mass (Da):31,788
Last modified:October 1, 1994 - v1
Checksum:i89F3E15B57437AE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11648 Genomic DNA Translation: AAA93052.1
AL939118 Genomic DNA Translation: CAC32306.1
PIRiS69774
RefSeqiNP_628217.1, NC_003888.3
WP_011029398.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAC32306; CAC32306; CAC32306
GeneIDi1099471
KEGGisco:SCO4035
PATRICifig|100226.15.peg.4098

Similar proteinsi

Entry informationi

Entry nameiRPOF_STRCO
AccessioniPrimary (citable) accession number: P37971
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 25, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health