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Protein

Type 1 fimbrin D-mannose specific adhesin

Gene

fimH

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity).By similarity

GO - Biological processi

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-552-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Type 1 fimbrin D-mannose specific adhesin
Alternative name(s):
Protein FimH
Gene namesi
Name:fimH
Ordered Locus Names:STM0547
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Fimbrium By similarity

GO - Cellular componenti

  • pilus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Fimbrium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000000921323 – 335Type 1 fimbrin D-mannose specific adhesinAdd BLAST313

Proteomic databases

PaxDbiP37925
PRIDEiP37925

Interactioni

Protein-protein interaction databases

STRINGi99287.STM0547

Structurei

3D structure databases

ProteinModelPortaliP37925
SMRiP37925
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108M66 Bacteria
ENOG410ZUTT LUCA
HOGENOMiHOG000267835
KOiK07350
OMAiQMPFGVQ
PhylomeDBiP37925

Family and domain databases

Gene3Di2.60.40.1090, 1 hit
InterProiView protein in InterPro
IPR000259 Adhesion_dom_fimbrial
IPR036937 Adhesion_dom_fimbrial_sf
IPR008966 Adhesion_dom_sf
PfamiView protein in Pfam
PF00419 Fimbrial, 1 hit
SUPFAMiSSF49401 SSF49401, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37925-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIYSALLLA GTALFFTHPA LATVCRNSNG TATDIFYDLS DVFTSGNNQP
60 70 80 90 100
GQVVTLPEKS GWVGVNATCP AGTTVNYTYR SYVSELPVQS TEGNFKYLKL
110 120 130 140 150
NDYLLGAMSI TDSVAGVFYP PRNYILMGVD YNVSQQKPFG VQDSKLVFKL
160 170 180 190 200
KVIRPFINMV TIPRQTMFTV YVTTSTGDAL STPVYTISYS GKVEVPQNCE
210 220 230 240 250
VNAGQVVEFD FGDIGASLFS QAGAGNRPQG VTPQTKTIAI KCTNVAAQAY
260 270 280 290 300
LSMRLEAEKA SGQAMVSDNP DLGFVVANSN GTPLTPNNLS SKIPFHLDDN
310 320 330
AAARVGIRAW PISVTGIKPA EGPFTARGYL RVDYD
Length:335
Mass (Da):36,102
Last modified:January 23, 2002 - v2
Checksum:i31EE8222C041D61D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti61G → A in AAA75420 (Ref. 1) Curated1
Sequence conflicti118F → S in AAA75420 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19338 Genomic DNA Translation: AAA75420.1
AE006468 Genomic DNA Translation: AAL19501.1
RefSeqiNP_459542.1, NC_003197.2
WP_000708653.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL19501; AAL19501; STM0547
GeneIDi1252067
KEGGistm:STM0547
PATRICifig|99287.12.peg.580

Similar proteinsi

Entry informationi

Entry nameiFIMH_SALTY
AccessioniPrimary (citable) accession number: P37925
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: January 23, 2002
Last modified: May 23, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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