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P37908 (YFJD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 117. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0053 inner membrane protein YfjD
Gene names
Name:yfjD
Synonyms:ypjE
Ordered Locus Names:b4461, JW5415
ORF Names:b2612/b2613
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Contains 1 DUF21 domain.

Sequence caution

The sequence BAA16497.2 differs from that shown. Reason: Erroneous initiation.

The sequence X07863 differs from that shown. Reason: Frameshift at positions 326, 331 and 348.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 428428UPF0053 inner membrane protein YfjD
PRO_0000088357

Regions

Topological domain1 – 33Cytoplasmic Potential
Transmembrane4 – 2421Helical; Potential
Topological domain25 – 6440Periplasmic Potential
Transmembrane65 – 8521Helical; Potential
Topological domain86 – 916Cytoplasmic Potential
Transmembrane92 – 11221Helical; Potential
Topological domain113 – 12917Periplasmic Potential
Transmembrane130 – 15021Helical; Potential
Topological domain151 – 428278Cytoplasmic Potential
Domain9 – 183175DUF21
Domain208 – 27063CBS 1
Domain272 – 33261CBS 2

Sequences

Sequence LengthMass (Da)Tools
P37908 [UniParc].

Last modified July 10, 2007. Version 5.
Checksum: 38456865EDBCB151

FASTA42848,044
        10         20         30         40         50         60 
MEHISTTTLI IILIIMVVIS AYFSGSETGM MTLNRYRLRH MAKQGNRSAK RVEKLLRKPD 

        70         80         90        100        110        120 
RLISLVLIGN NLVNILASAL GTIVGMRLYG DAGVAIATGV LTFVVLVFAE VLPKTIAALY 

       130        140        150        160        170        180 
PEKVAYPSSF LLAPLQILMM PLVWLLNAIT RMLMRMMGIK TDIVVSGSLS KEELRTIVHE 

       190        200        210        220        230        240 
SRSQISRRNQ DMLLSVLDLE KMTVDDIMVP RSEIIGIDIN DDWKSILRQL SHSPHGRIVL 

       250        260        270        280        290        300 
YRDSLDDAIS MLRVREAWRL MSEKKEFTKE TMLRAADEIY FVPEGTPLST QLVKFQRNKK 

       310        320        330        340        350        360 
KVGLVVNEYG DIQGLVTVED ILEEIVGDFT TSMSPTLAEE VTPQNDGSVI IDGTANVREI 

       370        380        390        400        410        420 
NKAFNWHLPE DDARTVNGVI LEALEEIPVA GTRVRIGEYD IDILDVQDNM IKQVKVFPVK 


PLRESVAE 

« Hide

References

« Hide 'large scale' references
[1]"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. expand/collapse author list , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005."
Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R., Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T., Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H., Thomson N.R., Wishart D., Wanner B.L.
Nucleic Acids Res. 34:1-9(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Sequence analysis and transcriptional regulation of the Escherichia coli grpE gene, encoding a heat shock protein."
Lipinska B., King J., Ang D., Georgopoulos C.
Nucleic Acids Res. 16:7545-7562(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 322-428.
Strain: B178.
[6]Rudd K.E.
Unpublished observations (AUG-1994)
Cited for: IDENTIFICATION.
[7]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAT48144.3.
AP009048 Genomic DNA. Translation: BAA16497.2. Different initiation.
X07863 Genomic DNA. No translation available.
RefSeqYP_026171.3. NC_000913.3.
YP_490835.1. NC_007779.1.

3D structure databases

ProteinModelPortalP37908.
SMRP37908. Positions 190-416.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-12070N.
IntActP37908. 2 interactions.
MINTMINT-1274766.
STRING511145.b4461.

Proteomic databases

PRIDEP37908.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT48144; AAT48144; b4461.
BAA16497; BAA16497; BAA16497.
GeneID12931626.
2847739.
KEGGecj:Y75_p2560.
eco:b4461.
PATRIC32120623. VBIEscCol129921_2710.

Organism-specific databases

EchoBASEEB2336.
EcoGeneEG12442. yfjD.

Phylogenomic databases

eggNOGCOG4536.
HOGENOMHOG000062298.
OMAAMMSLNR.
OrthoDBEOG60W7V4.
PhylomeDBP37908.
ProtClustDBPRK11573.

Enzyme and pathway databases

BioCycEcoCyc:G7356-MONOMER.
ECOL316407:JW5415-MONOMER.

Gene expression databases

GenevestigatorP37908.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR002550. DUF21.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
PF01595. DUF21. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 1 hit.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51371. CBS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP37908.

Entry information

Entry nameYFJD_ECOLI
AccessionPrimary (citable) accession number: P37908
Secondary accession number(s): P76600 expand/collapse secondary AC list , P76601, P77009, Q6BF70
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 10, 2007
Last modified: April 16, 2014
This is version 117 of the entry and version 5 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene