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Protein

UPF0053 inner membrane protein YfjD

Gene

yfjD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7356-MONOMER

Protein family/group databases

TCDBi9.A.40.2.4 the hlyc/corc (hcc) family

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 inner membrane protein YfjD
Gene namesi
Name:yfjD
Synonyms:ypjE
Ordered Locus Names:b4461, JW5415
ORF Names:b2612/b2613
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12442 yfjD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3CytoplasmicSequence analysis3
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Topological domaini25 – 64PeriplasmicSequence analysisAdd BLAST40
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Topological domaini86 – 91CytoplasmicSequence analysis6
Transmembranei92 – 112HelicalSequence analysisAdd BLAST21
Topological domaini113 – 129PeriplasmicSequence analysisAdd BLAST17
Transmembranei130 – 150HelicalSequence analysisAdd BLAST21
Topological domaini151 – 428CytoplasmicSequence analysisAdd BLAST278

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000883571 – 428UPF0053 inner membrane protein YfjDAdd BLAST428

Proteomic databases

PaxDbiP37908
PRIDEiP37908

Interactioni

Protein-protein interaction databases

BioGridi4260620, 11 interactors
DIPiDIP-12070N
IntActiP37908, 2 interactors
STRINGi316385.ECDH10B_2779

Structurei

3D structure databases

ProteinModelPortaliP37908
SMRiP37908
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 192CNNM transmembranePROSITE-ProRule annotationAdd BLAST191
Domaini208 – 270CBS 1PROSITE-ProRule annotationAdd BLAST63
Domaini272 – 332CBS 2PROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the UPF0053 family.Curated

Keywords - Domaini

CBS domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108JU6 Bacteria
COG4536 LUCA
HOGENOMiHOG000062298
InParanoidiP37908
OMAiLGELCPK
PhylomeDBiP37908

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR002550 CNNM
IPR036318 FAD-bd_2-like_sf
IPR005170 Transptr-assoc_dom
PfamiView protein in Pfam
PF00571 CBS, 1 hit
PF03471 CorC_HlyC, 1 hit
PF01595 DUF21, 1 hit
SMARTiView protein in SMART
SM01091 CorC_HlyC, 1 hit
SUPFAMiSSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 1 hit
PS51846 CNNM, 1 hit

Sequencei

Sequence statusi: Complete.

P37908-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHISTTTLI IILIIMVVIS AYFSGSETGM MTLNRYRLRH MAKQGNRSAK
60 70 80 90 100
RVEKLLRKPD RLISLVLIGN NLVNILASAL GTIVGMRLYG DAGVAIATGV
110 120 130 140 150
LTFVVLVFAE VLPKTIAALY PEKVAYPSSF LLAPLQILMM PLVWLLNAIT
160 170 180 190 200
RMLMRMMGIK TDIVVSGSLS KEELRTIVHE SRSQISRRNQ DMLLSVLDLE
210 220 230 240 250
KMTVDDIMVP RSEIIGIDIN DDWKSILRQL SHSPHGRIVL YRDSLDDAIS
260 270 280 290 300
MLRVREAWRL MSEKKEFTKE TMLRAADEIY FVPEGTPLST QLVKFQRNKK
310 320 330 340 350
KVGLVVNEYG DIQGLVTVED ILEEIVGDFT TSMSPTLAEE VTPQNDGSVI
360 370 380 390 400
IDGTANVREI NKAFNWHLPE DDARTVNGVI LEALEEIPVA GTRVRIGEYD
410 420
IDILDVQDNM IKQVKVFPVK PLRESVAE
Length:428
Mass (Da):48,044
Last modified:July 10, 2007 - v5
Checksum:i38456865EDBCB151
GO

Sequence cautioni

The sequence BAA16497 differs from that shown. Reason: Erroneous initiation.Curated
The sequence X07863 differs from that shown. Reason: Frameshift at positions 326, 331 and 348.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAT48144.3
AP009048 Genomic DNA Translation: BAA16497.2 Different initiation.
X07863 Genomic DNA No translation available.
RefSeqiWP_010723175.1, NZ_LN832404.1
YP_026171.3, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAT48144; AAT48144; b4461
BAA16497; BAA16497; BAA16497
GeneIDi2847739
KEGGiecj:JW5415
eco:b4461
PATRICifig|511145.12.peg.2710

Similar proteinsi

Entry informationi

Entry nameiYFJD_ECOLI
AccessioniPrimary (citable) accession number: P37908
Secondary accession number(s): P76600
, P76601, P77009, Q6BF70
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 143 of the entry and version 5 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health