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Protein

Universal stress protein F

Gene

uspF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: EcoliWiki

GO - Biological processi

  • cell adhesion Source: EcoCyc
  • response to oxidative stress Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6699-MONOMER.
ECOL316407:JW1370-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Universal stress protein F
Gene namesi
Name:uspF
Synonyms:ynaF, yzzL
Ordered Locus Names:b1376, JW1370
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12674. uspF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 144144Universal stress protein FPRO_0000147426Add
BLAST

Proteomic databases

EPDiP37903.
PaxDbiP37903.
PRIDEiP37903.

2D gel databases

SWISS-2DPAGEP37903.

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

BioGridi4262881. 7 interactions.
DIPiDIP-12739N.
IntActiP37903. 19 interactions.
STRINGi511145.b1376.

Structurei

3D structure databases

ProteinModelPortaliP37903.
SMRiP37903. Positions 2-144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal stress protein A family.Curated

Phylogenomic databases

eggNOGiENOG4108RW8. Bacteria.
COG0589. LUCA.
HOGENOMiHOG000238897.
InParanoidiP37903.
KOiK14061.
OMAiKNWRTEK.
OrthoDBiEOG6CCH61.
PhylomeDBiP37903.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PRINTSiPR01438. UNVRSLSTRESS.

Sequencei

Sequence statusi: Complete.

P37903-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRTILVPID ISDSELTQRV ISHVEEEAKI DDAEVHFLTV IPSLPYYASL
60 70 80 90 100
GLAYSAELPA MDDLKAEAKS QLEEIIKKFK LPTDRVHVHV EEGSPKDRIL
110 120 130 140
ELAKKIPAHM IIIASHRPDI TTYLLGSNAA AVVRHAECSV LVVR
Length:144
Mass (Da):16,017
Last modified:November 1, 1997 - v2
Checksum:iF30D0FC681EBF32D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74458.2.
AP009048 Genomic DNA. Translation: BAA14980.1.
PIRiC64888.
RefSeqiNP_415894.4. NC_000913.3.
WP_001300461.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74458; AAC74458; b1376.
BAA14980; BAA14980; BAA14980.
GeneIDi945948.
KEGGiecj:JW1370.
eco:b1376.
PATRICi32118036. VBIEscCol129921_1438.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74458.2.
AP009048 Genomic DNA. Translation: BAA14980.1.
PIRiC64888.
RefSeqiNP_415894.4. NC_000913.3.
WP_001300461.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37903.
SMRiP37903. Positions 2-144.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262881. 7 interactions.
DIPiDIP-12739N.
IntActiP37903. 19 interactions.
STRINGi511145.b1376.

2D gel databases

SWISS-2DPAGEP37903.

Proteomic databases

EPDiP37903.
PaxDbiP37903.
PRIDEiP37903.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74458; AAC74458; b1376.
BAA14980; BAA14980; BAA14980.
GeneIDi945948.
KEGGiecj:JW1370.
eco:b1376.
PATRICi32118036. VBIEscCol129921_1438.

Organism-specific databases

EchoBASEiEB2539.
EcoGeneiEG12674. uspF.

Phylogenomic databases

eggNOGiENOG4108RW8. Bacteria.
COG0589. LUCA.
HOGENOMiHOG000238897.
InParanoidiP37903.
KOiK14061.
OMAiKNWRTEK.
OrthoDBiEOG6CCH61.
PhylomeDBiP37903.

Enzyme and pathway databases

BioCyciEcoCyc:G6699-MONOMER.
ECOL316407:JW1370-MONOMER.

Miscellaneous databases

PROiP37903.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PRINTSiPR01438. UNVRSLSTRESS.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12."
    Link A.J., Robison K., Church G.M.
    Electrophoresis 18:1259-1313(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-12.
    Strain: K12 / EMG2.
  5. Cited for: PROTEIN SEQUENCE OF 1-11.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage."
    Gustavsson N., Diez A., Nystroem T.
    Mol. Microbiol. 43:107-117(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
  7. "Structural and nucleotide-binding properties of YajQ and YnaF, two Escherichia coli proteins of unknown function."
    Saveanu C., Miron S., Borza T., Craescu C.T., Labesse G., Gagyi C., Popescu A., Schaeffer F., Namane A., Laurent-Winter C., Barzu O., Gilles A.-M.
    Protein Sci. 11:2551-2560(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING.

Entry informationi

Entry nameiUSPF_ECOLI
AccessioniPrimary (citable) accession number: P37903
Secondary accession number(s): P76074, P76853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.