P37903 (USPF_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Universal stress protein F

Gene names

Name:	uspF
Synonyms:	ynaF, yzzL
Ordered Locus Names:	b1376, JW1370

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homodimer Probable.
Sequence similarities	Belongs to the universal stress protein A family.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	response to stress Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	Universal stress protein F		PRO_0000147426

Sequences

	Sequence		Length	Mass (Da)
	P37903 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: F30D0FC681EBF32D	FASTA	144	16,017
	10 20 30 40 50 60 MNRTILVPID ISDSELTQRV ISHVEEEAKI DDAEVHFLTV IPSLPYYASL GLAYSAELPA 70 80 90 100 110 120 MDDLKAEAKS QLEEIIKKFK LPTDRVHVHV EEGSPKDRIL ELAKKIPAHM IIIASHRPDI 130 140 TTYLLGSNAA AVVRHAECSV LVVR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Link A.J., Robison K., Church G.M. Electrophoresis 18:1259-1313(1997) [PubMed: 9298646] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-12. Strain: K12 / EMG2.
[5]	Pasquali C., Sanchez J.-C., Ravier F., Golaz O., Hughes G.J., Frutiger S., Paquet N., Wilkins M., Appel R.D., Bairoch A., Hochstrasser D.F. Submitted (SEP-1994) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-11. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]	"The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage." Gustavsson N., Diez A., Nystroem T. Mol. Microbiol. 43:107-117(2002) [PubMed: 11849540] [Abstract] Cited for: GENE NAME. Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
[7]	"Structural and nucleotide-binding properties of YajQ and YnaF, two Escherichia coli proteins of unknown function." Saveanu C., Miron S., Borza T., Craescu C.T., Labesse G., Gagyi C., Popescu A., Schaeffer F., Namane A., Laurent-Winter C., Barzu O., Gilles A.-M. Protein Sci. 11:2551-2560(2002) [PubMed: 12381839] [Abstract] Cited for: 3D-STRUCTURE MODELING.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74458.2. AP009048 Genomic DNA. Translation: BAA14980.1.
PIR	C64888.
RefSeq	NP_415894.4. NC_000913.2.
3D structure databases
ProteinModelPortal	P37903.
SMR	P37903. Positions 2-144.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12739N.
IntAct	P37903. 19 interactions.
2D gel databases
SWISS-2DPAGE	P37903.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000002695; EBESCP00000002695; EBESCG00000002196. EBESCT00000016884; EBESCP00000016175; EBESCG00000015943.
GeneID	945948.
GenomeReviews	Gene locus JW1370 in contig AP009048_GR. Gene locus b1376 in contig U00096_GR.
KEGG	ecj:JW1370. eco:b1376.
PATRIC	32118036. VBIEscCol129921_1438.
Organism-specific databases
EchoBASE	EB2539.
EcoGene	EG12674. uspF.
Phylogenomic databases
eggNOG	COG0589.
GeneTree	EBGT00050000010679.
HOGENOM	HBG733992.
OMA	HVVRYAK.
PhylomeDB	P37903.
ProtClustDB	PRK15005.
Enzyme and pathway databases
BioCyc	EcoCyc:G6699-MONOMER.
Gene expression databases
Genevestigator	P37903.
Family and domain databases
InterPro	IPR014729. Rossmann-like_a/b/a_fold. IPR006015. Universal_stress_UspA. IPR006016. UspA. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K14061.
Pfam	PF00582. Usp. 1 hit. [Graphical view]
PRINTS	PR01438. UNVRSLSTRESS.
ProtoNet	Search...

Entry information

Entry name

USPF_ECOLI

Accession

Primary (citable) accession number: P37903
Secondary accession number(s): P76074, P76853

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program