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Protein

Glutamate/aspartate import solute-binding protein

Gene

gltI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.1 Publication3 Publications

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6359-MONOMER.
MetaCyc:G6359-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.4. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate/aspartate import solute-binding proteinCurated
Gene namesi
Name:gltI
Synonyms:ybeJ, yzzK
Ordered Locus Names:b0655, JW5092
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12700. gltI.

Subcellular locationi

  • Periplasm 1 Publication

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000003175823 – 302Glutamate/aspartate import solute-binding proteinAdd BLAST280

Proteomic databases

EPDiP37902.
PaxDbiP37902.
PRIDEiP37902.

2D gel databases

SWISS-2DPAGEiP37902.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (GltL), two transmembrane proteins (GltJ and GltK) and a solute-binding protein (GltI).1 Publication

Protein-protein interaction databases

BioGridi4260829. 6 interactors.
DIPiDIP-11361N.
IntActiP37902. 1 interactor.
STRINGi316385.ECDH10B_0724.

Structurei

3D structure databases

ProteinModelPortaliP37902.
SMRiP37902.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107RP9. Bacteria.
COG0834. LUCA.
HOGENOMiHOG000031898.
InParanoidiP37902.
KOiK10001.
PhylomeDBiP37902.

Family and domain databases

InterProiView protein in InterPro
IPR001638. Solute-binding_3/MltF_N.
PfamiView protein in Pfam
PF00497. SBP_bac_3. 1 hit.
SMARTiView protein in SMART
SM00062. PBPb. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37902-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLRKPATAI LALALSAGLA QADDAAPAAG STLDKIAKNG VIVVGHRESS
60 70 80 90 100
VPFSYYDNQQ KVVGYSQDYS NAIVEAVKKK LNKPDLQVKL IPITSQNRIP
110 120 130 140 150
LLQNGTFDFE CGSTTNNVER QKQAAFSDTI FVVGTRLLTK KGGDIKDFAN
160 170 180 190 200
LKDKAVVVTS GTTSEVLLNK LNEEQKMNMR IISAKDHGDS FRTLESGRAV
210 220 230 240 250
AFMMDDALLA GERAKAKKPD NWEIVGKPQS QEAYGCMLRK DDPQFKKLMD
260 270 280 290 300
DTIAQVQTSG EAEKWFDKWF KNPIPPKNLN MNFELSDEMK ALFKEPNDKA

LN
Length:302
Mass (Da):33,420
Last modified:November 1, 1997 - v2
Checksum:i6FFC3321040152EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40856.1.
U00096 Genomic DNA. Translation: AAC73756.1.
AP009048 Genomic DNA. Translation: BAA35307.2.
U10981 Genomic DNA. No translation available.
PIRiE64800.
RefSeqiNP_415188.1. NC_000913.3.
WP_001177086.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73756; AAC73756; b0655.
BAA35307; BAA35307; BAA35307.
GeneIDi946938.
KEGGiecj:JW5092.
eco:b0655.
PATRICifig|1411691.4.peg.1613.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGLTI_ECOLI
AccessioniPrimary (citable) accession number: P37902
Secondary accession number(s): P41408
, P77612, Q9R7T1, Q9R7T3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: November 1, 1997
Last modified: July 5, 2017
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families