Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate/aspartate import solute-binding protein

Gene

gltI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.1 Publication3 Publications

GO - Molecular functioni

  • aspartate binding Source: EcoCyc
  • glutamate binding Source: EcoCyc

GO - Biological processi

  • L-aspartate transmembrane transport Source: EcoCyc
  • L-glutamate transmembrane transport Source: EcoCyc

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6359-MONOMER
MetaCyc:G6359-MONOMER

Protein family/group databases

TCDBi3.A.1.3.4 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate/aspartate import solute-binding proteinCurated
Gene namesi
Name:gltI
Synonyms:ybeJ, yzzK
Ordered Locus Names:b0655, JW5092
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12700 gltI

Subcellular locationi

  • Periplasm 1 Publication

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000003175823 – 302Glutamate/aspartate import solute-binding proteinAdd BLAST280

Proteomic databases

EPDiP37902
PaxDbiP37902
PRIDEiP37902

2D gel databases

SWISS-2DPAGEiP37902

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (GltL), two transmembrane proteins (GltJ and GltK) and a solute-binding protein (GltI).1 Publication

Protein-protein interaction databases

BioGridi426082918 interactors.
DIPiDIP-11361N
IntActiP37902 1 interactor.
STRINGi316385.ECDH10B_0724

Structurei

3D structure databases

ProteinModelPortaliP37902
SMRiP37902
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107RP9 Bacteria
COG0834 LUCA
HOGENOMiHOG000031898
InParanoidiP37902
KOiK10001
OMAiAMNADKQ
PhylomeDBiP37902

Family and domain databases

InterProiView protein in InterPro
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF00497 SBP_bac_3, 1 hit
SMARTiView protein in SMART
SM00062 PBPb, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37902-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLRKPATAI LALALSAGLA QADDAAPAAG STLDKIAKNG VIVVGHRESS
60 70 80 90 100
VPFSYYDNQQ KVVGYSQDYS NAIVEAVKKK LNKPDLQVKL IPITSQNRIP
110 120 130 140 150
LLQNGTFDFE CGSTTNNVER QKQAAFSDTI FVVGTRLLTK KGGDIKDFAN
160 170 180 190 200
LKDKAVVVTS GTTSEVLLNK LNEEQKMNMR IISAKDHGDS FRTLESGRAV
210 220 230 240 250
AFMMDDALLA GERAKAKKPD NWEIVGKPQS QEAYGCMLRK DDPQFKKLMD
260 270 280 290 300
DTIAQVQTSG EAEKWFDKWF KNPIPPKNLN MNFELSDEMK ALFKEPNDKA

LN
Length:302
Mass (Da):33,420
Last modified:November 1, 1997 - v2
Checksum:i6FFC3321040152EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40856.1
U00096 Genomic DNA Translation: AAC73756.1
AP009048 Genomic DNA Translation: BAA35307.2
U10981 Genomic DNA No translation available.
PIRiE64800
RefSeqiNP_415188.1, NC_000913.3
WP_001177086.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73756; AAC73756; b0655
BAA35307; BAA35307; BAA35307
GeneIDi946938
KEGGiecj:JW5092
eco:b0655
PATRICifig|1411691.4.peg.1613

Similar proteinsi

Entry informationi

Entry nameiGLTI_ECOLI
AccessioniPrimary (citable) accession number: P37902
Secondary accession number(s): P41408
, P77612, Q9R7T1, Q9R7T3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: November 1, 1997
Last modified: April 25, 2018
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome